|DB00272||Betazole||For use clinically to test gastric secretory function.|
|DB00482||Celecoxib||For the relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis [FDA label].|
|DB00812||Phenylbutazone||For the treatment of backache and ankylosing spondylitis|
|DB00889||Granisetron||For the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy (including high dose cisplatin), postoperation, and radiation (including total body irradiation and daily fractionated abdominal radiation).|
|DB01129||Rabeprazole||For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.|
|DB01138||Sulfinpyrazone||For the treatment of gout and gouty arthritis.|
|DB01424||Aminophenazone||Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water.|
|DB01435||Antipyrine||Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes.
In combination with benzocaine in otic solutions, antipyrine is indicated for the symptomatic relief of acute otitis media arising from various etiologies. |
|DB04817||Metamizole||Used in the past as a powerful painkiller and fever reducer.|
|DB05262||Oxypurinol||Intended for the treatment of congestive heart failure and hyperuricemia.|
|DB05586||Facinicline||Investigated for use/treatment in alzheimer's disease, neurologic disorders, and schizophrenia and schizoaffective disorders.|
|DB06070||SNX-5422||Investigated for use/treatment in cancer/tumors (unspecified).|
|DB06080||ABT-869||Investigated for use/treatment in leukemia (myeloid), myelodysplastic syndrome, and solid tumors.|
|DB06266||Lonidamine||Investigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified).|
|DB06626||Axitinib||Used in kidney cell cancer and investigated for use/treatment in pancreatic and thyroid cancer.|
|DB06729||Sulfaphenazole||For the treatment bacterial infections.|
|DB09084||Benzydamine||Available predominantly as a liquid mouthwash, oromucosal spray, or topical cream, benzydamine is most frequently employed as a locally acting analgesic and anti-inflammatory treatment for the relief of painful inflammatory conditions.
When formulated as a mouthwash or spray, benzydamine may be used to treat traumatic conditions like pharyngitis following tonsillectomy or the use of a naso-gastric tube, inflammatory conditions like pharyngitis, aphthous ulcers and oral ulceration due to radiation therapy, dentistry operations and procedures, or more general conditions like sore throat, sore tongue, sore gums, mouth ulcers, or discomfort caused by dentures. [L1121]
When used as a topical cream, benzydamine may be employed to relieve symptoms associated with painful inflammatory conditions of the muscolo-skeletal system including acute inflammatory disorders such as myalgia and bursitis or traumatic conditions like sprains, strains, bruises, sore muscles, stiff joints, or even the after-effects of fractures. [ L1123]|
|DB11793||Niraparib||Niraparib is indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy|
|DB12243||Edaravone||Indicated for improving neurological symptoms and damage from acute ischemic stroke and delaying disease progression of ALS.|
|DB13501||Bendazac||Prior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the prescription medication bendazac lysine for the indication of managing the level of vision in patients with mild to moderate cataracts to facilitate delaying the need for surgical intervention [A39863, A39869, A39890].
Elsewhere bendazac may still be available in a limited capacity as a non-prescription topical cream product for treating conditions like local pain, inflammation, dermatitis, eczema, pruritis, hives, insect bites, burns, erythema, and others [L4780] - although such products may also be facing general discontinuation [L4781].|