Histamine Agents

Drugs used for their actions on histaminergic systems. Included are drugs that act at histamine receptors, affect the life cycle of histamine, or affect the state of histaminergic cells.
DrugDrug NameDrug Indication
DB00272BetazoleFor use clinically to test gastric secretory function.
DB00283ClemastineFor the relief of symptoms associated with allergic rhinitis such as sneezing, rhinorrhea, pruritus and acrimation. Also for the management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Used as self-medication for temporary relief of symptoms associated with the common cold.
DB00341CetirizineFor the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
DB00342TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DB00354BuclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
DB00366DoxylamineUsed alone as a short-term sleep aid, in combination with other drugs as a night-time cold and allergy relief drug. Also used in combination with Vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.
DB00370MirtazapineFor the treatment of major depressive disorder.
DB00392EthopropazineFor use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
DB00405DexbrompheniramineFor treatment and relief of symptoms of allergies, hay fever, and colds
DB00427TriprolidineFor the symptomatic relief of seasonal or perennial allergic rhinitis or nonallergic rhinitis; allergic conjunctivitis; and mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Also used in combination with other agents for the symptomatic relief of symptoms associated with the common cold.
DB00434CyproheptadineFor treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.
DB00455LoratadineA self-medication that is used alone or in combination with pseudoephedrine sulfate for the symptomatic relief of seasonal allergic rhinitis. Also used for the symptomatic relief of pruritus, erythema, and urticaria associated with chronic idiopathic urticaria in patients (not for children under 6 unless directed by a clincian).
DB00501CimetidineFor the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
DB00557HydroxyzineFor symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
DB00568CinnarizineFor the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
DB00585NizatidineFor the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.
DB00637AstemizoleAstemizole was indicated for use in the relieving allergy symptoms, particularly rhinitis and conjunctivitis. It has been withdrawn from the market however due to concerns of arrhythmias.
DB00719AzatadineFor the relief of the symptoms of upper respiratory mucosal congestion in perennial and allergic rhinitis, and for the relief of nasal congestion and eustachian t.b. congestion.
DB00737MeclizineFor the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness.
DB00748CarbinoxamineFor symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis, as well as allergic conjunctivitis caused by foods and inhaled allergens. Also for the relief of allergic reactions to blood or plasma, and the symptomatic management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema.
DB00751EpinastineFor the prevention of itching associated with allergic conjunctivitis.
DB00768OlopatadineFor the treatment of ocular itching associated with allergic conjunctivitis.
DB00792TripelennamineUsed for the symptomatic relief of hypersensitivity reactions, coughs, and the common cold.
DB00835BrompheniramineFor the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.
DB00863RanitidineUsed in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
DB00885PemirolastFor the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis
DB00920KetotifenIndicated as an add-on or prophylactic oral medication in the chronic treatment of mild atopic asthmatic children. Also used as self-medication for the temporary relief of itching of the eye due to allergic conjunctivitis (ophthalmic).
DB00927FamotidineFor the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
DB00950FexofenadineFor management of Seasonal allergic rhinitis
DB00967DesloratadineFor the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.
DB00972AzelastineFor the symptomatic treatment of seasonal allergic rhinitis and non-allergic rhinitis, as well as symptomatic relief of ocular itching associated with allergic conjunctivitis.
DB00985DimenhydrinateUsed for treating vertigo, motion sickness, and nausea associated with pregnancy.
DB01069PromethazineFor the treatment of allergic disorders, and nausea/vomiting.
DB01071MequitazineFor the treatment of Hay fever, urticaria (hives) and allergic rhinitis
DB01075DiphenhydramineFor the treatment of symptoms associated with Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite.
DB01084EmedastineFor the temporary relief of the signs and symptoms of allergic conjunctivitis.
DB01106LevocabastineAs an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
DB01114ChlorphenamineFor the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.
DB01142DoxepinDoxepin is used for the treatment of depression and/or anxiety. It can also be used for chronic urticaria and in the management of pain.
DB01176CyclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
DB01246AlimemazineUsed to prevent and relieve allergic conditions which cause pruritus (itching) and urticaria (some allergic skin reactions).
DB01619PhenindamineUsed to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.
DB01620PheniraminePheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria.
DB03568Butyric AcidNot Available
DB04819MethapyrileneNot Available
DB04841FlunarizineUsed in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
DB04905TesmilifeneIntended for the treatment of various forms of cancer.
DB05381HistamineHistamine phosphate is indicated as a diagnostic aid for evaluation of gastric acid secretory function.
DB06148MianserinFor the treatment of depression.
DB06282LevocetirizineLevocetirizine is indicated for the relief of symptoms associated with allergic rhinitis (seasonal and perennial) in adults and children 6 years of age and older.
DB06678EsmirtazapineInvestigated for use/treatment in insomnia and sleep disorders.
DB06691MepyramineMepyramine is a first generation antihistamine used in treating allergies, ymptomatic relief of hypersensitivity reaction, and in pruritic skin disorders.
DB06698BetahistineFor the reduction of episodes of vertigo association with Ménière's disease.
DB06766AlcaftadineFor the prevention of itching associated with allergic conjunctivitis.
DB06794LodoxamideIndicated in the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
DB07615TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DB08799AntazolineUsed to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
DB08800ChloropyramineFor the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions.
DB08801DimetindeneIndicated as symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hey fever and perennial rhinitis, food and drug allergies; pruritus of various origins, except pruritus due to cholestasis; insect bites. Dimethindene is also indicated for pruritus in eruptive skin diseases such as chicken-pox. Dimethindene can also be used as an adjuvant in eczema and other pruriginous dermatoses of allergic origin.
DB08802IsothipendylFor the topical treatment of itching associated with allergic reactions.
DB08805MetiamidePotential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
DB08806Roxatidine acetateFor the treatment of disorders of the upper gastro-intestinal region that are due to an excess of hydrochloric acid in the gastric juice, i.e. duodenal ulcers, benign gastric ulcers. Also for prophylaxis of recurrent gastric and duodenal ulcers
DB08967DimetotiazineNot Available
DB09007ChlorphenoxamineNot Available
DB09488AcrivastineFor the relief of symptoms associated with seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion.
DB09555Dexchlorpheniramine maleateDexchlorpheniramine can be used in the treatment of perennial and seasonal allergic rhinitis, vasomotor rhiniti, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, and dermographism.
DB11235ThonzylamineNot Available
DB11742EbastineNot Available
DB12017OzagrelNot Available
DB12523MizolastineNot Available
DB12770LafutidineNot Available
DB12877OxatomideNot Available
DB12884LavoltidineNot Available
DB13679DexchlorpheniramineNot Available
DrugDrug NameTargetType
DB00272BetazoleHistamine H2 receptortarget
DB00283ClemastineHistamine H1 receptortarget
DB00283ClemastineCytochrome P450 2D6enzyme
DB00283ClemastineCytochrome P450 3A4enzyme
DB00341CetirizineHistamine H1 receptortarget
DB00342TerfenadineHistamine H1 receptortarget
DB00342TerfenadinePotassium voltage-gated channel subfamily H member 2target
DB00342TerfenadineCytochrome P450 3A4enzyme
DB00342TerfenadineCytochrome P450 2C9enzyme
DB00342TerfenadineCytochrome P450 2D6enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M3target
DB00342TerfenadineCytochrome P450 3A5enzyme
DB00342TerfenadineCytochrome P450 3A7enzyme
DB00342TerfenadineMultidrug resistance protein 1transporter
DB00342TerfenadineCytochrome P450 2C8enzyme
DB00342TerfenadineCytochrome P450 2J2enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M1target
DB00342TerfenadineMuscarinic acetylcholine receptor M5target
DB00342TerfenadineMuscarinic acetylcholine receptor M4target
DB00342TerfenadineMuscarinic acetylcholine receptor M2target
DB00354BuclizineHistamine H1 receptortarget
DB00354BuclizineMuscarinic acetylcholine receptor M1target
DB00366DoxylamineHistamine H1 receptortarget
DB00366DoxylamineMuscarinic acetylcholine receptor M1target
DB00366DoxylamineCYP2B proteinenzyme
DB00366DoxylamineNuclear receptor subfamily 1 group I member 3target
DB00370Mirtazapine5-hydroxytryptamine receptor 2Atarget
DB00370Mirtazapine5-hydroxytryptamine receptor 3Atarget
DB00370MirtazapineAlpha-2A adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Ctarget
DB00370MirtazapineKappa-type opioid receptortarget
DB00370MirtazapineHistamine H1 receptortarget
DB00370MirtazapineCytochrome P450 1A2enzyme
DB00370MirtazapineCytochrome P450 3A4enzyme
DB00370MirtazapineCytochrome P450 2D6enzyme
DB00370MirtazapineCytochrome P450 2C8enzyme
DB00370MirtazapineCytochrome P450 2C9enzyme
DB00370MirtazapineAlpha-2C adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 7target
DB00370MirtazapineAlpha-1 adrenergic receptorstarget
DB00370MirtazapineD(2) dopamine receptortarget
DB00370MirtazapineD(3) dopamine receptortarget
DB00370MirtazapineSodium-dependent noradrenaline transportertarget
DB00370MirtazapineSodium-dependent serotonin transportertarget
DB00370MirtazapineSodium-dependent dopamine transportertarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Btarget
DB00370MirtazapineD(1) dopamine receptortarget
DB00370MirtazapineHistamine H3 receptortarget
DB00370MirtazapineAlpha-1A adrenergic receptortarget
DB00370MirtazapineBeta-1 adrenergic receptortarget
DB00370MirtazapineBeta-2 adrenergic receptortarget
DB00392EthopropazineGlutamate receptor ionotropic, NMDA 3Atarget
DB00392EthopropazineMuscarinic acetylcholine receptor M1target
DB00392EthopropazineCholinesteraseenzyme
DB00392EthopropazineMuscarinic acetylcholine receptor M2target
DB00405DexbrompheniramineHistamine H1 receptortarget
DB00427TriprolidineHistamine H1 receptortarget
DB00427TriprolidineCytochrome P450 2D6enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00455LoratadineHistamine H1 receptortarget
DB00455LoratadineCytochrome P450 3A4enzyme
DB00455LoratadineCytochrome P450 2C19enzyme
DB00455LoratadineCytochrome P450 2D6enzyme
DB00455LoratadineCytochrome P450 2C8enzyme
DB00455LoratadineMultidrug resistance protein 1transporter
DB00455LoratadineCytochrome P450 2C9enzyme
DB00455LoratadinePotassium voltage-gated channel subfamily H member 2target
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineCytochrome P450 3A7enzyme
DB00501CimetidineMultidrug resistance protein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00557HydroxyzineHistamine H1 receptortarget
DB00557HydroxyzineCytochrome P450 2D6enzyme
DB00568CinnarizineHistamine H1 receptortarget
DB00568CinnarizineD(2) dopamine receptortarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00568CinnarizineCytochrome P450 2D6enzyme
DB00568CinnarizineCytochrome P450 2B6enzyme
DB00568CinnarizineCytochrome P450 2C9enzyme
DB00568CinnarizineCytochrome P450 1A1enzyme
DB00568CinnarizineCytochrome P450 1A2enzyme
DB00568CinnarizineCytochrome P450 2A6enzyme
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00568CinnarizineD(1) dopamine receptortarget
DB00568CinnarizineMuscarinic acetylcholine receptortarget
DB00585NizatidineHistamine H2 receptortarget
DB00585NizatidineMultidrug resistance protein 1transporter
DB00585NizatidineCholinesteraseenzyme
DB00637AstemizoleHistamine H1 receptortarget
DB00637AstemizolePotassium voltage-gated channel subfamily H member 2target
DB00637AstemizoleCytochrome P450 3A4enzyme
DB00637AstemizoleCytochrome P450 3A5enzyme
DB00637AstemizoleCytochrome P450 3A7enzyme
DB00637AstemizoleMultidrug resistance protein 1transporter
DB00637AstemizoleCytochrome P450 2D6enzyme
DB00637AstemizoleCytochrome P450 2J2enzyme
DB00637AstemizolePotassium voltage-gated channel subfamily H member 1target
DB00637AstemizoleMicrotubule-associated protein tautarget
DB00719AzatadineHistamine H1 receptortarget
DB00719AzatadineCytochrome P450 3A4enzyme
DB00737MeclizineHistamine H1 receptortarget
DB00737MeclizineCytochrome P450 1A2enzyme
DB00737MeclizineNuclear receptor subfamily 1 group I member 3target
DB00748CarbinoxamineHistamine H1 receptortarget
DB00748CarbinoxamineCytochrome P450 2B6enzyme
DB00748CarbinoxamineCytochrome P450 2C19enzyme
DB00748CarbinoxamineCytochrome P450 2C8enzyme
DB00748CarbinoxamineCytochrome P450 2C9enzyme
DB00748CarbinoxamineCytochrome P450 2D6enzyme
DB00748CarbinoxamineCytochrome P450 2E1enzyme
DB00748CarbinoxamineCytochrome P450 3A4enzyme
DB00751EpinastineHistamine H1 receptortarget
DB00751EpinastineHistamine H2 receptortarget
DB00751EpinastineAlpha-1A adrenergic receptortarget
DB00751EpinastineAlpha-2A adrenergic receptortarget
DB00751Epinastine5-hydroxytryptamine receptor 2Atarget
DB00751Epinastine5-hydroxytryptamine receptor 7target
DB00751EpinastineMultidrug resistance protein 1transporter
DB00751EpinastineCytochrome P450 2B6enzyme
DB00751EpinastineCytochrome P450 2D6enzyme
DB00751EpinastineCytochrome P450 3A4enzyme
DB00768OlopatadineHistamine H1 receptortarget
DB00768OlopatadineProtein S100-A1target
DB00768OlopatadineProtein S100-A12target
DB00768OlopatadineProtein S100-Btarget
DB00768OlopatadineProtein S100-A13target
DB00768OlopatadineProtein S100-A2target
DB00768OlopatadineCytochrome P450 3A4enzyme
DB00792TripelennamineHistamine H1 receptortarget
DB00792TripelennamineCytochrome P450 2D6enzyme
DB00835BrompheniramineHistamine H1 receptortarget
DB00835BrompheniramineMuscarinic acetylcholine receptor M1target
DB00835BrompheniramineMuscarinic acetylcholine receptor M2target
DB00835BrompheniramineMuscarinic acetylcholine receptor M3target
DB00835BrompheniramineMuscarinic acetylcholine receptor M4target
DB00835BrompheniramineMuscarinic acetylcholine receptor M5target
DB00835BrompheniramineCytochrome P450 2B6enzyme
DB00835BrompheniramineCytochrome P450 2C19enzyme
DB00835BrompheniramineCytochrome P450 2C8enzyme
DB00835BrompheniramineCytochrome P450 2C9enzyme
DB00835BrompheniramineCytochrome P450 2D6enzyme
DB00835BrompheniramineCytochrome P450 2E1enzyme
DB00835BrompheniramineCytochrome P450 3A4enzyme
DB00863RanitidineHistamine H2 receptortarget
DB00863RanitidineCytochrome P450 1A2enzyme
DB00863RanitidineCytochrome P450 2C19enzyme
DB00863RanitidineCytochrome P450 2D6enzyme
DB00863RanitidineSolute carrier family 22 member 1transporter
DB00863RanitidineMultidrug resistance protein 1transporter
DB00863RanitidineSolute carrier family 22 member 8transporter
DB00863RanitidineCytochrome P450 3A4enzyme
DB00863RanitidineCytochrome P450 3A5enzyme
DB00863RanitidineAcetylcholinesterasetarget
DB00863RanitidineCholinesterasetarget
DB00920KetotifenHistamine H1 receptortarget
DB00920Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineCytochrome P450 2C19enzyme
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00950FexofenadineHistamine H1 receptortarget
DB00950FexofenadineMultidrug resistance protein 1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 2B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1A2transporter
DB00950FexofenadineCytochrome P450 2D6enzyme
DB00950FexofenadineSolute carrier organic anion transporter family member 1B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B3transporter
DB00967DesloratadineHistamine H1 receptortarget
DB00967DesloratadineCytochrome P450 2C9enzyme
DB00967DesloratadineCytochrome P450 2C19enzyme
DB00967DesloratadineCytochrome P450 1A2enzyme
DB00967DesloratadineCytochrome P450 2D6enzyme
DB00967DesloratadineMultidrug resistance protein 1transporter
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineMultidrug resistance protein 1transporter
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2B6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00985DimenhydrinateHistamine H1 receptortarget
DB01069PromethazineD(2) dopamine receptortarget
DB01069PromethazineHistamine H1 receptortarget
DB01069PromethazineMuscarinic acetylcholine receptor M4target
DB01069PromethazineMuscarinic acetylcholine receptor M1target
DB01069PromethazineMuscarinic acetylcholine receptor M5target
DB01069PromethazineAlpha-1A adrenergic receptortarget
DB01069Promethazine5-hydroxytryptamine receptor 2Atarget
DB01069PromethazineMuscarinic acetylcholine receptor M2target
DB01069PromethazineMuscarinic acetylcholine receptor M3target
DB01069PromethazineCalmodulintarget
DB01069PromethazineCytochrome P450 2D6enzyme
DB01069PromethazineCytochrome P450 2B6enzyme
DB01069PromethazineMultidrug resistance protein 1transporter
DB01069PromethazineCytochrome P450 2C9enzyme
DB01069PromethazineHistamine H2 receptortarget
DB01071MequitazineHistamine H1 receptortarget
DB01071MequitazineCytochrome P450 2D6enzyme
DB01071MequitazineCytochrome P450 3A4enzyme
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 1A2enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineCytochrome P450 2C18enzyme
DB01075DiphenhydramineCytochrome P450 2B6enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 1transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB01084EmedastineHistamine H1 receptortarget
DB01106LevocabastineNeurotensin receptor type 2target
DB01106LevocabastineHistamine H1 receptortarget
DB01114ChlorphenamineHistamine H1 receptortarget
DB01114ChlorphenamineCytochrome P450 3A4enzyme
DB01114ChlorphenamineCytochrome P450 2D6enzyme
DB01114ChlorphenamineSodium-dependent serotonin transportertarget
DB01114ChlorphenamineSodium-dependent noradrenaline transportertarget
DB01114ChlorphenamineSodium-dependent dopamine transportertarget
DB01114ChlorphenamineCytochrome P450 3A5enzyme
DB01114ChlorphenamineCytochrome P450 3A7enzyme
DB01114ChlorphenamineSolute carrier family 22 member 2transporter
DB01114ChlorphenamineSolute carrier family 22 member 1transporter
DB01142DoxepinSodium-dependent serotonin transportertarget
DB01142DoxepinSodium-dependent noradrenaline transportertarget
DB01142DoxepinHistamine H1 receptortarget
DB01142DoxepinHistamine H2 receptortarget
DB01142DoxepinCytochrome P450 2D6enzyme
DB01142DoxepinMuscarinic acetylcholine receptor M1target
DB01142DoxepinMuscarinic acetylcholine receptor M2target
DB01142DoxepinMuscarinic acetylcholine receptor M3target
DB01142DoxepinMuscarinic acetylcholine receptor M4target
DB01142DoxepinMuscarinic acetylcholine receptor M5target
DB01142DoxepinAlpha-1A adrenergic receptortarget
DB01142Doxepin5-hydroxytryptamine receptor 1Atarget
DB01142Doxepin5-hydroxytryptamine receptor 2Atarget
DB01142DoxepinD(2) dopamine receptortarget
DB01142DoxepinCytochrome P450 2C19enzyme
DB01142DoxepinCytochrome P450 2C9enzyme
DB01142DoxepinCytochrome P450 1A2enzyme
DB01142DoxepinAlpha-1-acid glycoprotein 1carrier
DB01142DoxepinMultidrug resistance protein 1transporter
DB01142Doxepin5-hydroxytryptamine receptor 2Btarget
DB01142Doxepin5-hydroxytryptamine receptor 2Ctarget
DB01142DoxepinAlpha-1B adrenergic receptortarget
DB01142DoxepinAlpha-1D adrenergic receptortarget
DB01142DoxepinAlpha-2A adrenergic receptortarget
DB01142DoxepinAlpha-2B adrenergic receptortarget
DB01142DoxepinAlpha-2C adrenergic receptortarget
DB01142DoxepinCytochrome P450 3A4enzyme
DB01142Doxepin5-hydroxytryptamine receptor 6target
DB01142DoxepinHistamine H4 receptortarget
DB01142DoxepinPotassium voltage-gated channel subfamily H member 2target
DB01176CyclizineHistamine H1 receptortarget
DB01176CyclizineEstrogen sulfotransferasetarget
DB01176CyclizineCytochrome P450 2C9enzyme
DB01246AlimemazineHistamine H1 receptortarget
DB01246AlimemazineCytochrome P450 3A4enzyme
DB01619PhenindamineHistamine H1 receptortarget
DB01620PheniramineHistamine H1 receptortarget
DB01620PheniramineNuclear receptor subfamily 1 group I member 3target
DB03568Butyric Acid(S)-2-haloacid dehalogenasetarget
DB03568Butyric AcidCholinesterasetarget
DB03568Butyric Acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03568Butyric AcidCholinesteraseenzyme
DB04841FlunarizineHistamine H1 receptortarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB04841FlunarizineCalmodulintarget
DB04841FlunarizineCytochrome P450 2D6enzyme
DB04841FlunarizineCytochrome P450 2B6enzyme
DB04841FlunarizineCytochrome P450 2C9enzyme
DB04841FlunarizineCytochrome P450 1A1enzyme
DB04841FlunarizineCytochrome P450 1A2enzyme
DB04841FlunarizineCytochrome P450 2A6enzyme
DB04905TesmilifeneMultidrug resistance protein 1target
DB04905TesmilifeneHistamine H1 receptortarget
DB04905TesmilifeneCytochrome P450 3A4enzyme
DB04905TesmilifeneCytochrome P450 2D6enzyme
DB04905TesmilifeneCytochrome P450 1A1enzyme
DB05381HistamineHistamine H1 receptortarget
DB05381HistamineHistamine H2 receptortarget
DB05381HistamineHistamine H3 receptortarget
DB05381HistamineHistamine N-methyltransferaseenzyme
DB05381HistamineSolute carrier family 22 member 2transporter
DB05381HistamineSolute carrier family 22 member 1transporter
DB05381HistamineSolute carrier family 22 member 3transporter
DB05381HistamineSolute carrier family 22 member 5transporter
DB05381HistamineHistamine H4 receptortarget
DB05381HistamineCytochrome P450 2C9enzyme
DB05381HistamineCytochrome P450 2D6enzyme
DB05381HistamineCytochrome P450 3A4enzyme
DB05381HistamineSynaptic vesicular amine transportertarget
DB06148MianserinHistamine H1 receptortarget
DB06148MianserinAlpha-2A adrenergic receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 2Atarget
DB06148Mianserin5-hydroxytryptamine receptor 2Ctarget
DB06148MianserinCytochrome P450 2D6enzyme
DB06148MianserinSodium-dependent serotonin transportertarget
DB06148MianserinCytochrome P450 3A4enzyme
DB06148MianserinCytochrome P450 1A2enzyme
DB06148MianserinCytochrome P450 2B6enzyme
DB06148MianserinSodium-dependent noradrenaline transportertarget
DB06148MianserinHistamine H4 receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 1Atarget
DB06148MianserinAlpha-2C adrenergic receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 2Btarget
DB06148Mianserin5-hydroxytryptamine receptor 1Ftarget
DB06148MianserinAlpha-2B adrenergic receptortarget
DB06148MianserinD(3) dopamine receptortarget
DB06148MianserinKappa-type opioid receptortarget
DB06148MianserinSodium-dependent dopamine transportertarget
DB06148Mianserin5-hydroxytryptamine receptor 7target
DB06148MianserinD(2) dopamine receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 6target
DB06148MianserinAlpha-1 adrenergic receptorstarget
DB06148MianserinD(1) dopamine receptortarget
DB06282LevocetirizineHistamine H1 receptortarget
DB06282LevocetirizineCytochrome P450 3A4enzyme
DB06678EsmirtazapineCytochrome P450 2D6enzyme
DB06678EsmirtazapineHistamine H1 receptortarget
DB06678Esmirtazapine5-hydroxytryptamine receptor 2target
DB06678EsmirtazapineAlpha-2 adrenergic receptorstarget
DB06691MepyramineCytochrome P450 2D6enzyme
DB06691MepyramineHistamine H1 receptortarget
DB06691MepyramineSolute carrier family 22 member 4transporter
DB06691MepyramineSolute carrier family 22 member 5transporter
DB06698BetahistineHistamine H1 receptortarget
DB06698BetahistineHistamine H3 receptortarget
DB06766AlcaftadineHistamine H1 receptortarget
DB07615TranilastHematopoietic prostaglandin D synthasetarget
DB08799AntazolineHistamine H1 receptortarget
DB08800ChloropyramineHistamine H1 receptortarget
DB08801DimetindeneMuscarinic acetylcholine receptor M2target
DB08801DimetindeneHistamine H1 receptortarget
DB08802IsothipendylHistamine H1 receptortarget
DB08805MetiamideHistamine H2 receptortarget
DB08806Roxatidine acetateHistamine H2 receptortarget
DB09488AcrivastineHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateCytochrome P450 2D6enzyme
DB09555Dexchlorpheniramine maleateHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 1carrier
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 2carrier
DB09555Dexchlorpheniramine maleateCytochrome P450 3A4enzyme