Histamine Agents

Drugs used for their actions on histaminergic systems. Included are drugs that act at histamine receptors, affect the life cycle of histamine, or affect the state of histaminergic cells.
DrugDrug NameDrug Description
DB00272BetazoleFor use clinically to test gastric secretory function.
DB00283ClemastineAn antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.
DB00341CetirizineA selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria.
DB00342TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DB00354BuclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
DB00366DoxylamineAn antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy.
DB00370MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
DB00392ProfenamineAn antidyskinetic phenothiazine used to treat the symptoms of Parkinson's disease.
DB00405DexbrompheniramineAn antihistamine used to treat allergy symptoms including upper respiratory tract symptoms.
DB00427TriprolidineA sedating antihistamine combined with pseudoephedrine and guaifenesin in various types of cold and allergy medications to relieve allergy symptoms, hay fever and common cold symptoms, and to aid in sleep.
DB00434CyproheptadineA serotonin and histamine antagonist used in the treatment of allergy symptoms and in combination with epinephrine in the treatment of anaphylaxis.
DB00501CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
DB00557HydroxyzineAn antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.
DB00568CinnarizineFor the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
DB00585NizatidineAn H2 receptor antagonist used to treat GERD and a variety of ulcers.
DB00637AstemizoleA second generation antihistamine used to treat allergy symptoms.
DB00719AzatadineAn H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion.
DB00737MeclizineA histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness.
DB00748CarbinoxamineA first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions.
DB00751EpinastineAn H1 receptor antagonist used to prevent itching in allergic conjunctivitis.
DB00768OlopatadineA histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
DB00792TripelennamineA histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold.
DB00835BrompheniramineA histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
DB00885PemirolastA medication used to treat allergies such as hay fever and allergic conjunctivitis.
DB00920KetotifenA histamine H1 receptor blocker used to treat mild asthma and allergic conjunctivitis.
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB00950FexofenadineAn antihistamine used to treat seasonal allergic rhinitis.
DB00967DesloratadineA second generation tricyclic antihistamine used to treat seasonal and non seasonal allergic rhinitis, pruritus, and urticaria.
DB00972AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
DB00985DimenhydrinateA medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness.
DB01069PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
DB01071MequitazineFor the treatment of Hay fever, urticaria (hives) and allergic rhinitis
DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DB01084EmedastineA selective H1-receptor antagonist used topically to manage symptoms of allergic conjunctivitis.
DB01106LevocabastineA selective histamine H1 receptor antagonist indicated for the management of seasonal allergic conjunctivitis symptoms.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB01142DoxepinA psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
DB01176CyclizineAn antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo.
DB01246AlimemazineAn antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.
DB01619PhenindamineUsed to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.
DB01620PheniramineAn antihistamine used to treat allergic rhinitis and pruritus.
DB03568Butyric AcidA four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
DB04819MethapyrileneMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
DB04841FlunarizineA selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.
DB04905TesmilifeneIntended for the treatment of various forms of cancer.
DB05381HistamineAn ingredient of topical drugs for the relief of joint pain or muscle aches and pains.
DB06148MianserinFor the treatment of depression.
DB06282LevocetirizineAn H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria.
DB06678EsmirtazapineInvestigated for use/treatment in insomnia and sleep disorders.
DB06691MepyramineAn antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.
DB06698BetahistineAn antivertigo agent used for the reduction of episodes of vertigo association with Ménière's disease.
DB06766AlcaftadineA H1 histamine receptor antagonist for ophthalmic use to prevent itching associated with allergic conjunctivitis.
DB06794LodoxamideAn ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
DB07615TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DB08799AntazolineAn antihistamine agent used for the symptomatic treatment of nasal congestion and allergic conjunctivitis.
DB08800ChloropyramineFor the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions.
DB08801DimetindeneIndicated as symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hey fever and perennial rhinitis, food and drug allergies; pruritus of various origins, except...
DB08802IsothipendylFor the topical treatment of itching associated with allergic reactions.
DB08805MetiamidePotential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
DB08806Roxatidine acetateFor the treatment of disorders of the upper gastro-intestinal region that are due to an excess of hydrochloric acid in the gastric juice, i.e. duodenal ulcers, benign gastric ulcers. Also...
DB08967DimetotiazineDimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.
DB09007ChlorphenoxamineChlorphenoxamine is marketed under the name Phenoxene. It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
DB09488AcrivastineAn antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion.
DB09555Dexchlorpheniramine maleateA first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
DB11235ThonzylamineThozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms [FDA Label]. It is typically a part of combination over the counter...
DB11742EbastineEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
DB12017OzagrelOzagrel has been used in trials studying the treatment of Dry Eye Syndromes.
DB12523MizolastineMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
DB12770LafutidineLafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD).
DB12877OxatomideOxatomide has been used in trials studying the treatment of Muscular Dystrophy, Duchenne.
DB12884LavoltidineLavoltidine has been used in trials studying the diagnostic of Reflux, Gastroesophageal and Gastroesophageal Reflux Disease.
DB13489BamipineNot Annotated
DB13679DexchlorpheniramineDexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjuctive therapy for allergic and anaphylactic...
DB13711TritoqualineNot Annotated
DB13713QuifenadineNot Annotated
DB13466DeptropineNot Annotated
DrugDrug NameTargetType
DB00272BetazoleHistamine H2 receptortarget
DB00283ClemastineHistamine H1 receptortarget
DB00283ClemastineCytochrome P450 2D6enzyme
DB00341CetirizineHistamine H1 receptortarget
DB00341CetirizineP-glycoprotein 1transporter
DB00342TerfenadineHistamine H1 receptortarget
DB00342TerfenadinePotassium voltage-gated channel subfamily H member 2target
DB00342TerfenadineCytochrome P450 3A4enzyme
DB00342TerfenadineCytochrome P450 2D6enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M3target
DB00342TerfenadineCytochrome P450 3A5enzyme
DB00342TerfenadineCytochrome P450 3A7enzyme
DB00342TerfenadineP-glycoprotein 1transporter
DB00342TerfenadineCytochrome P450 2C8enzyme
DB00342TerfenadineCytochrome P450 2J2enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M1target
DB00342TerfenadineMuscarinic acetylcholine receptor M5target
DB00342TerfenadineMuscarinic acetylcholine receptor M4target
DB00342TerfenadineMuscarinic acetylcholine receptor M2target
DB00342TerfenadineBile salt export pumptransporter
DB00354BuclizineHistamine H1 receptortarget
DB00354BuclizineMuscarinic acetylcholine receptor M1target
DB00366DoxylamineHistamine H1 receptortarget
DB00366DoxylamineMuscarinic acetylcholine receptor M1target
DB00366DoxylamineCYP2B proteinenzyme
DB00366DoxylamineNuclear receptor subfamily 1 group I member 3target
DB00370Mirtazapine5-hydroxytryptamine receptor 2Atarget
DB00370Mirtazapine5HT3 serotonin receptortarget
DB00370MirtazapineAlpha-2A adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Ctarget
DB00370MirtazapineKappa-type opioid receptortarget
DB00370MirtazapineHistamine H1 receptortarget
DB00370MirtazapineCytochrome P450 1A2enzyme
DB00370MirtazapineCytochrome P450 3A4enzyme
DB00370MirtazapineCytochrome P450 2D6enzyme
DB00370MirtazapineAlpha-1 adrenergic receptorstarget
DB00370MirtazapineSodium-dependent serotonin transportertransporter
DB00392ProfenamineGlutamate receptor ionotropic, NMDA 3Atarget
DB00392ProfenamineMuscarinic acetylcholine receptor M1target
DB00392ProfenamineCholinesteraseenzyme
DB00392ProfenamineMuscarinic acetylcholine receptor M2target
DB00405DexbrompheniramineHistamine H1 receptortarget
DB00427TriprolidineHistamine H1 receptortarget
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineP-glycoprotein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineMultidrug and toxin extrusion protein 2transporter
DB00557HydroxyzineHistamine H1 receptortarget
DB00557HydroxyzineCytochrome P450 2D6enzyme
DB00557HydroxyzineCytochrome P450 3A4enzyme
DB00557HydroxyzineCytochrome P450 3A5enzyme
DB00568CinnarizineHistamine H1 receptortarget
DB00568CinnarizineDopamine D2 receptortarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00568CinnarizineCytochrome P450 2D6enzyme
DB00568CinnarizineCytochrome P450 2B6enzyme
DB00568CinnarizineCytochrome P450 2C9enzyme
DB00568CinnarizineCytochrome P450 1A1enzyme
DB00568CinnarizineCytochrome P450 1A2enzyme
DB00568CinnarizineCytochrome P450 2A6enzyme
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00568CinnarizineD(1) dopamine receptortarget
DB00568CinnarizineMuscarinic acetylcholine receptortarget
DB00568CinnarizineCytochrome P450 3A4enzyme
DB00585NizatidineHistamine H2 receptortarget
DB00585NizatidineP-glycoprotein 1transporter
DB00585NizatidineCholinesteraseenzyme
DB00637AstemizoleHistamine H1 receptortarget
DB00637AstemizolePotassium voltage-gated channel subfamily H member 2target
DB00637AstemizoleCytochrome P450 3A4enzyme
DB00637AstemizoleCytochrome P450 3A5enzyme
DB00637AstemizoleCytochrome P450 3A7enzyme
DB00637AstemizoleP-glycoprotein 1transporter
DB00637AstemizoleCytochrome P450 2D6enzyme
DB00637AstemizoleCytochrome P450 2J2enzyme
DB00637AstemizolePotassium voltage-gated channel subfamily H member 1target
DB00637AstemizoleMicrotubule-associated protein tautarget
DB00637AstemizoleBile salt export pumptransporter
DB00719AzatadineHistamine H1 receptortarget
DB00719AzatadineCytochrome P450 3A4enzyme
DB00737MeclizineHistamine H1 receptortarget
DB00737MeclizineNuclear receptor subfamily 1 group I member 3target
DB00737MeclizineCytochrome P450 2D6enzyme
DB00737MeclizineSerum albumincarrier
DB00748CarbinoxamineHistamine H1 receptortarget
DB00751EpinastineHistamine H1 receptortarget
DB00751EpinastineHistamine H2 receptortarget
DB00751EpinastineAlpha-1A adrenergic receptortarget
DB00751EpinastineAlpha-2A adrenergic receptortarget
DB00751Epinastine5-hydroxytryptamine receptor 2Atarget
DB00751Epinastine5-hydroxytryptamine receptor 7target
DB00751EpinastineP-glycoprotein 1transporter
DB00751EpinastineCytochrome P450 2B6enzyme
DB00751EpinastineCytochrome P450 2D6enzyme
DB00751EpinastineCytochrome P450 3A4enzyme
DB00768OlopatadineHistamine H1 receptortarget
DB00768OlopatadineProtein S100-A1target
DB00768OlopatadineProtein S100-A12target
DB00768OlopatadineProtein S100-Btarget
DB00768OlopatadineProtein S100-A13target
DB00768OlopatadineProtein S100-A2target
DB00768OlopatadineCytochrome P450 3A4enzyme
DB00768OlopatadineSerum albumincarrier
DB00768OlopatadineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00768OlopatadineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00768OlopatadineP-glycoprotein 1transporter
DB00768OlopatadineHistamine H2 receptortarget
DB00768OlopatadineHistamine H3 receptortarget
DB00792TripelennamineHistamine H1 receptortarget
DB00792TripelennamineCytochrome P450 2D6enzyme
DB00835BrompheniramineHistamine H1 receptortarget
DB00835BrompheniramineMuscarinic acetylcholine receptor M1target
DB00835BrompheniramineMuscarinic acetylcholine receptor M2target
DB00835BrompheniramineMuscarinic acetylcholine receptor M3target
DB00835BrompheniramineMuscarinic acetylcholine receptor M4target
DB00835BrompheniramineMuscarinic acetylcholine receptor M5target
DB00920KetotifenHistamine H1 receptortarget
DB00920Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00950FexofenadineHistamine H1 receptortarget
DB00950FexofenadineP-glycoprotein 1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 2B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1A2transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B3transporter
DB00950FexofenadineSolute carrier family 22 member 8transporter
DB00967DesloratadineHistamine H1 receptortarget
DB00967DesloratadineP-glycoprotein 1transporter
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineP-glycoprotein 1transporter
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00972AzelastineHistamine H2 receptortarget
DB00972AzelastinePhospholipase A2target
DB00972AzelastineLeukotriene C4 synthasetarget
DB00972AzelastineCytochrome P450 2B6enzyme
DB00985DimenhydrinateHistamine H1 receptortarget
DB01069PromethazineDopamine D2 receptortarget
DB01069PromethazineHistamine H1 receptortarget
DB01069PromethazineMuscarinic acetylcholine receptor M4target
DB01069PromethazineMuscarinic acetylcholine receptor M1target
DB01069PromethazineMuscarinic acetylcholine receptor M5target
DB01069PromethazineAlpha-1A adrenergic receptortarget
DB01069Promethazine5-hydroxytryptamine receptor 2Atarget
DB01069PromethazineMuscarinic acetylcholine receptor M2target
DB01069PromethazineMuscarinic acetylcholine receptor M3target
DB01069PromethazineCalmodulintarget
DB01069PromethazineCytochrome P450 2D6enzyme
DB01069PromethazineCytochrome P450 2B6enzyme
DB01069PromethazineP-glycoprotein 1transporter
DB01069PromethazineCytochrome P450 2C9enzyme
DB01069PromethazineHistamine H2 receptortarget
DB01071MequitazineHistamine H1 receptortarget
DB01071MequitazineCytochrome P450 2D6enzyme
DB01071MequitazineCytochrome P450 3A4enzyme
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB01084EmedastineHistamine H1 receptortarget
DB01106LevocabastineNeurotensin receptor type 2target
DB01106LevocabastineHistamine H1 receptortarget
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB01142DoxepinSodium-dependent serotonin transportertarget
DB01142DoxepinSodium-dependent noradrenaline transportertarget
DB01142DoxepinHistamine H1 receptortarget
DB01142DoxepinHistamine H2 receptortarget
DB01142DoxepinCytochrome P450 2D6enzyme
DB01142DoxepinMuscarinic acetylcholine receptor M1target
DB01142DoxepinMuscarinic acetylcholine receptor M2target
DB01142DoxepinMuscarinic acetylcholine receptor M3target
DB01142DoxepinMuscarinic acetylcholine receptor M4target
DB01142DoxepinMuscarinic acetylcholine receptor M5target
DB01142DoxepinAlpha-1A adrenergic receptortarget
DB01142Doxepin5-hydroxytryptamine receptor 1Atarget
DB01142Doxepin5-hydroxytryptamine receptor 2Atarget
DB01142DoxepinCytochrome P450 2C19enzyme
DB01142DoxepinCytochrome P450 2C9enzyme
DB01142DoxepinCytochrome P450 1A2enzyme
DB01142DoxepinP-glycoprotein 1transporter
DB01142Doxepin5-hydroxytryptamine receptor 2Btarget
DB01142Doxepin5-hydroxytryptamine receptor 2Ctarget
DB01142DoxepinAlpha-1B adrenergic receptortarget
DB01142DoxepinAlpha-1D adrenergic receptortarget
DB01142DoxepinCytochrome P450 3A4enzyme
DB01142Doxepin5-hydroxytryptamine receptor 6target
DB01142DoxepinHistamine H4 receptortarget
DB01142DoxepinPotassium voltage-gated channel subfamily H member 2target
DB01142DoxepinSerum albumincarrier
DB01142DoxepinAlpha-1-acid glycoprotein 1carrier
DB01176CyclizineHistamine H1 receptortarget
DB01176CyclizineEstrogen sulfotransferasetarget
DB01176CyclizineCytochrome P450 2C9enzyme
DB01246AlimemazineHistamine H1 receptortarget
DB01619PhenindamineHistamine H1 receptortarget
DB01620PheniramineHistamine H1 receptortarget
DB01620PheniramineNuclear receptor subfamily 1 group I member 3target
DB01620PheniramineHistamine H4 receptortarget
DB03568Butyric Acid(S)-2-haloacid dehalogenasetarget
DB03568Butyric AcidCholinesterasetarget
DB03568Butyric Acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03568Butyric AcidCholinesteraseenzyme
DB04841FlunarizineHistamine H1 receptortarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB04841FlunarizineCalmodulintarget
DB04841FlunarizineCytochrome P450 2D6enzyme
DB04841FlunarizineCytochrome P450 2C9enzyme
DB04841FlunarizineCytochrome P450 1A1enzyme
DB04841FlunarizineCytochrome P450 1A2enzyme
DB04841FlunarizineCytochrome P450 2A6enzyme
DB04841FlunarizineCytochrome P450 3A4enzyme
DB04905TesmilifeneP-glycoprotein 1target
DB04905TesmilifeneHistamine H1 receptortarget
DB04905TesmilifeneCytochrome P450 3A4enzyme
DB04905TesmilifeneCytochrome P450 2D6enzyme
DB04905TesmilifeneCytochrome P450 1A1enzyme
DB05381HistamineHistamine H1 receptortarget
DB05381HistamineHistamine H2 receptortarget
DB05381HistamineHistamine H3 receptortarget
DB05381HistamineHistamine N-methyltransferaseenzyme
DB05381HistamineSolute carrier family 22 member 2transporter
DB05381HistamineSolute carrier family 22 member 1transporter
DB05381HistamineSolute carrier family 22 member 3transporter
DB05381HistamineSolute carrier family 22 member 5transporter
DB05381HistamineHistamine H4 receptortarget
DB05381HistamineSynaptic vesicular amine transportertarget
DB06148MianserinHistamine H1 receptortarget
DB06148MianserinAlpha-2A adrenergic receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 2Atarget
DB06148Mianserin5-hydroxytryptamine receptor 2Ctarget
DB06148MianserinCytochrome P450 2D6enzyme
DB06148MianserinSodium-dependent serotonin transportertarget
DB06148MianserinCytochrome P450 3A4enzyme
DB06148MianserinCytochrome P450 1A2enzyme
DB06148MianserinCytochrome P450 2B6enzyme
DB06148MianserinSodium-dependent noradrenaline transportertarget
DB06148MianserinHistamine H4 receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 1Atarget
DB06148MianserinAlpha-2C adrenergic receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 2Btarget
DB06148Mianserin5-hydroxytryptamine receptor 1Ftarget
DB06148MianserinAlpha-2B adrenergic receptortarget
DB06148MianserinDopamine D3 receptortarget
DB06148MianserinKappa-type opioid receptortarget
DB06148MianserinSodium-dependent dopamine transportertarget
DB06148Mianserin5-hydroxytryptamine receptor 7target
DB06148MianserinDopamine D2 receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 6target
DB06148MianserinAlpha-1 adrenergic receptorstarget
DB06148MianserinD(1) dopamine receptortarget
DB06282LevocetirizineHistamine H1 receptortarget
DB06282LevocetirizineSolute carrier family 22 member 11transporter
DB06282LevocetirizineCytochrome P450 3A4enzyme
DB06282LevocetirizineSerum albumincarrier
DB06678EsmirtazapineCytochrome P450 2D6enzyme
DB06678EsmirtazapineHistamine H1 receptortarget
DB06678Esmirtazapine5-hydroxytryptamine receptor 2target
DB06678EsmirtazapineAlpha-2 adrenergic receptorstarget
DB06691MepyramineCytochrome P450 2D6enzyme
DB06691MepyramineHistamine H1 receptortarget
DB06691MepyramineSolute carrier family 22 member 4transporter
DB06691MepyramineSolute carrier family 22 member 5transporter
DB06698BetahistineHistamine H1 receptortarget
DB06698BetahistineHistamine H3 receptortarget
DB06766AlcaftadineHistamine H1 receptortarget
DB07615TranilastHematopoietic prostaglandin D synthasetarget
DB07615TranilastCytochrome P450 3A4enzyme
DB07615TranilastCytochrome P450 2C9enzyme
DB08799AntazolineHistamine H1 receptortarget
DB08800ChloropyramineHistamine H1 receptortarget
DB08801DimetindeneMuscarinic acetylcholine receptor M2target
DB08801DimetindeneHistamine H1 receptortarget
DB08802IsothipendylHistamine H1 receptortarget
DB08805MetiamideHistamine H2 receptortarget
DB08806Roxatidine acetateHistamine H2 receptortarget
DB09488AcrivastineHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateCytochrome P450 2D6enzyme
DB09555Dexchlorpheniramine maleateHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 1carrier
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 2carrier
DB09555Dexchlorpheniramine maleateCytochrome P450 3A4enzyme
DB11235ThonzylamineHistamine H1 receptortarget
DB11235ThonzylamineMuscarinic acetylcholine receptor M1target
DB11235ThonzylamineMuscarinic acetylcholine receptor M2target
DB11235ThonzylamineMuscarinic acetylcholine receptor M3target
DB11235ThonzylamineMuscarinic acetylcholine receptor M4target
DB11235ThonzylamineMuscarinic acetylcholine receptor M5target
DB11742EbastineCytochrome P450 3A4enzyme
DB12523MizolastineCytochrome P450 2D6enzyme
DB13679DexchlorpheniramineCytochrome P450 2D6enzyme