Compounds also known as tetrahydropyridines with general molecular formula (CH2)4NH.
DrugDrug NameDrug Description
DB00283ClemastineAn antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.
DB00387ProcyclidineAn antispasmodic drug used to treat parkinsonism of various types and in the treatment of extrapyramidal symptoms.
DB00561DoxapramA short acting respiratory stimulant used to treat acute respiratory insufficiency in COPD patients.
DB00593EthosuximideAn anticonvulsant used to treat petit mal seizures.
DB00832PhensuximideFor the treatment of epilepsy.
DB00986GlycopyrroniumAn anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
DB01090PentoliniumUsed to produce controlled hypotension during surgical procedures and in hypertensive crises.
DB01190ClindamycinAn antibiotic used to treat serious infections caused by susceptible anaerobic bacteria, such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, and dental infections.
DB01202LevetiracetamA novel anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy.
DB01244BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
DB01627LincomycinAn antibiotic indicated only for the treatment of serious infections, and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate.
DB01954RolipramA phosphodiesterase inhibitor with antidepressant properties.
DB02492GhavamiolNot Available
DB02852Domoic AcidNot Available
DB03088Pidolic acidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in...
DB04599AniracetamCompound with anti-depressive properties used as a mental performance enhancer.
DB05102RupintrivirInvestigated for use/treatment in viral infection.
DB05246MethsuximideA succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures.
DB05541BrivaracetamAn anticonvulsant used for the treatment of partial-onset seizures that functions by binding to synaptic vesicle glycoprotein 2A (SV2A) in the brain.
DB06812Povidone-iodineA topical antiseptic agent used for the treatment and prevention of infection in wounds.
DB06817RaltegravirAn antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.
DB07374AnisomycinAnisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.
DB09210PiracetamIndicated in adult patients suffering from myoclonus of cortical origin, irrespective of aetiology, and should be used in combination with other anti-myoclonic therapies .
DB11061PovidoneWhen in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns.
DB11364PidotimodFor use as immunostimulant therapy for treatment of cell-mediated immunosuppression with respiratory or urinary infections .
DB11537PirlimycinPirlimycin hydrochloride is an antibiotic belonging to the lincosamide class. Often marketed as Pirsue, this drug is used to treat mastitis in cattle.
DB11868EtiracetamEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
DB12200TivantinibTivantinib has been investigated in Solid Tumors.
DB12224Oxothiazolidinecarboxylic acidProcysteine has been used in trials studying the treatment of HIV Infections.
DB12521Methyl pyrrolidoneN Methyl Pyrrolidone is under investigation for the treatment of Multiple Myeloma.
DB13082NefiracetamNefiracetam has been used in trials studying the treatment of Alzheimer's Disease.
DB13376SuccinimideNot Annotated
DB13459PecilocinNot Annotated
DB05885SeletracetamInvestigated for use/treatment in epilepsy.
DB12353UlodesineUlodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.
DB04876VildagliptinA once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.
DB06199AtrasentanInvestigated for use/treatment in prostate cancer and cancer/tumors (unspecified).
DB15157VoruciclibVoruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
DrugDrug NameTargetType
DB00283ClemastineHistamine H1 receptortarget
DB00283ClemastineCytochrome P450 2D6enzyme
DB00387ProcyclidineMuscarinic acetylcholine receptor M1target
DB00387ProcyclidineMuscarinic acetylcholine receptor M2target
DB00387ProcyclidineMuscarinic acetylcholine receptor M4target
DB00387ProcyclidineMuscarinic acetylcholine receptor M3target
DB00561DoxapramPotassium channel subfamily K member 3target
DB00561DoxapramPotassium channel subfamily K member 9target
DB00593EthosuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00593EthosuximideCytochrome P450 3A4enzyme
DB00593EthosuximideCytochrome P450 2E1enzyme
DB00593EthosuximideCytochrome P450 3A Subfamilyenzyme
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M1target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M3target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M2target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-10target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-3target
DB01090PentoliniumNeuronal acetylcholine receptor subunit beta-4target
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S ribosomal RNAtarget
DB01202LevetiracetamSynaptic vesicle glycoprotein 2Atarget
DB01202LevetiracetamP-glycoprotein 1transporter
DB01202LevetiracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB01244BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB01244BepridilSodium/potassium-transporting ATPase subunit alpha-1target
DB01244BepridilPotassium voltage-gated channel subfamily KQT member 1target
DB01244BepridilTroponin C, slow skeletal and cardiac musclestarget
DB01244BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01244BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01244BepridilP-glycoprotein 1transporter
DB01244BepridilCytochrome P450 2D6enzyme
DB01244BepridilPotassium voltage-gated channel subfamily H member 2target
DB01244BepridilCytochrome P450 3A4enzyme
DB01627Lincomycin50S ribosomal protein L10target
DB01954RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01954RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB02492GhavamiolAlpha-mannosidase 2target
DB02852Domoic AcidGlutamate receptor ionotropic, kainate 2target
DB03088Pidolic acidAlpha-amylase 2Btarget
DB03088Pidolic acidAngiogenintarget
DB03088Pidolic acidChondroitinase-Btarget
DB03088Pidolic acidAlpha-amylase 1target
DB03088Pidolic acidVascular endothelial growth factor Atarget
DB03088Pidolic acidPancreatic alpha-amylasetarget
DB03088Pidolic acidIg lambda-1 chain C regionstarget
DB03088Pidolic acidIg lambda chain V-II region MGCtarget
DB03088Pidolic acidTrefoil factor 2target
DB03088Pidolic acidCytochrome c2target
DB03088Pidolic acidDisintegrin and metalloproteinase domain-containing protein 28target
DB03088Pidolic acidEndo-1,4-beta-xylanasetarget
DB03088Pidolic acidDissimilatory copper-containing nitrite reductasetarget
DB03088Pidolic acidKeratin-associated protein 5-2target
DB03088Pidolic acidOrexintarget
DB03088Pidolic acidC-C motif chemokine 8target
DB03088Pidolic acidCytochrome c'target
DB03088Pidolic acidPancreatic alpha-amylaseenzyme
DB04599Aniracetam5-hydroxytryptamine receptor 2Atarget
DB04599AniracetamDopamine D2 receptortarget
DB04599AniracetamGlutamate receptor 2target
DB04599AniracetamGlutamate receptor 3target
DB05102RupintrivirGenome polyproteintarget
DB05246MethsuximideCytochrome P450 2C19enzyme
DB05246MethsuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB05541BrivaracetamSynaptic vesicle glycoprotein 2Atarget
DB05541BrivaracetamSodium channel proteintarget
DB05541BrivaracetamCytochrome P450 3A4enzyme
DB05541BrivaracetamCytochrome P450 2C19enzyme
DB05541BrivaracetamCytochrome P450 2B6enzyme
DB05541BrivaracetamCytochrome P450 2C9enzyme
DB06817RaltegravirUDP-glucuronosyltransferase 1-1enzyme
DB07374Anisomycin60S ribosomal protein L10-liketarget
DB07374Anisomycin60S ribosomal protein L13atarget
DB07374Anisomycin60S ribosomal protein L23target
DB07374Anisomycin60S ribosomal protein L15target
DB07374Anisomycin60S ribosomal protein L19target
DB07374Anisomycin60S ribosomal protein L23atarget
DB07374AnisomycinProbable ribosome biogenesis protein RLP24target
DB07374Anisomycin60S ribosomal protein L26-like 1target
DB07374Anisomycin60S ribosomal protein L8target
DB07374Anisomycin60S ribosomal protein L37target
DB07374Anisomycin60S ribosomal protein L3target
DB07374Anisomycin60S ribosomal protein L11target
DB07374AnisomycinNHP2-like protein 1target
DB12200TivantinibHepatocyte growth factor receptortarget
DB05885SeletracetamSynaptic vesicle glycoprotein 2Atarget
DB05885SeletracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB05885SeletracetamGlycine receptor (alpha-1/beta)target
DB05885SeletracetamCytochrome P450 3A4enzyme
DB04876VildagliptinDipeptidyl peptidase 4target
DB06199AtrasentanEndothelin-1 receptortarget