DrugDrug NameDrug Indication
DB00283ClemastineFor the relief of symptoms associated with allergic rhinitis such as sneezing, rhinorrhea, pruritus and acrimation. Also for the management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Used as self-medication for temporary relief of symptoms associated with the common cold.
DB00387ProcyclidineFor the treatment of all forms of Parkinson's Disease, as well as control of extrapyramidal reactions induced by antipsychotic agents.
DB00561DoxapramFor use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.
DB00593EthosuximideFor the treatment of petit mal epilepsy.
DB00832PhensuximideFor the treatment of epilepsy.
DB00986GlycopyrroniumFor use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and free acidity of gastric secretions and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. Also used to treat chronic obstructive pulmonary disease (COPD).
DB01090PentoliniumUsed to produce controlled hypotension during surgical procedures and in hypertensive crises.
DB01190ClindamycinFor the treatment of serious infections caused by susceptible anaerobic bacteria, including Bacteroides spp., Peptostreptococcus, anaerobic streptococci, Clostridium spp., and microaerophilic streptococci. May be useful in polymicrobic infections such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, aspiration pneumonia and dental infections. May also be used to treat MSSA and respiratory infections caused by S. pneumoniae and S. pyogenes in patients who are intolerant to other indicated antibiotics or who are infected with resistant organism. May be used vaginally to treat vaginosis caused by Gardnerella vaginosa. Clindamycin reduces the toxin producing effects of S. aureus and S. pyogenes and as such, may be particularly useful for treating necrotizing fasciitis. May be used topically to treat acne.
DB01202LevetiracetamUsed as adjunctive therapy in the treatment of partial onset seizures in adults and children 4 years of age and older with epilepsy.
DB01244BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
DB01627LincomycinLincomycin is an antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
DB01954RolipramNot Available
DB02492GhavamiolNot Available
DB02852Domoic AcidNot Available
DB03088Pidolic AcidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in a variety of non-prescription, over-the-counter dietary supplement products for cognitive or memory enhancement, there are many studies that suggest that such products or such supplementation do not elicit any kind of cognitive benefit to users [A32981, A32982]. In fact, the general suggestion for any such pidolic acid product is to exercise caution in their recommendation as much more research is necessary [A32981]. Pidolic acid and sodium pidolic acid are, however, used to some extent in skin and hair conditioning agents owing to their humectant characteristics [F53].
DB04599AniracetamNot Available
DB05102RupintrivirInvestigated for use/treatment in viral infection.
DB05246MethsuximideFor the control of absence (petit mal) seizures that are refractory to other drugs.
DB05541BrivaracetamUsed as adjunctive therapy for partial-onset seizures in patients 16 years of age or older.
DB06812Povidone-iodineFor topical application in the treatment and prevention of infection in wounds.
DB06817RaltegravirFor the treatment of HIV-1 infection in conjunction with other antiretrovirals.
DB07374AnisomycinNot Available
DB09210PiracetamIndicated in adult patients suffering from myoclonus of cortical origin, irrespective of aetiology, and should be used in combination with other anti-myoclonic therapies [L1125].
DB11061PovidoneWhen in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns.
DB11364PidotimodFor use as immunostimulant therapy for treatment of cell-mediated immunosuppression with respiratory or urinary infections [L929].
DB11537PirlimycinNot Available
DB11868EtiracetamNot Available
DB12200TivantinibNot Available
DB12224Oxothiazolidinecarboxylic acidNot Available
DB12521Methyl pyrrolidoneNot Available
DB13082NefiracetamNot Available
DB13376SuccinimideNot Available
DB13459PecilocinNot Available
DB05885SeletracetamInvestigated for use/treatment in epilepsy.
DB12353UlodesineNot Available
DrugDrug NameTargetType
DB00283ClemastineHistamine H1 receptortarget
DB00283ClemastineCytochrome P450 2D6enzyme
DB00387ProcyclidineMuscarinic acetylcholine receptor M1target
DB00387ProcyclidineMuscarinic acetylcholine receptor M2target
DB00387ProcyclidineMuscarinic acetylcholine receptor M4target
DB00387ProcyclidineMuscarinic acetylcholine receptor M3target
DB00561DoxapramPotassium channel subfamily K member 3target
DB00561DoxapramPotassium channel subfamily K member 9target
DB00593EthosuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00593EthosuximideCytochrome P450 3A4enzyme
DB00593EthosuximideCytochrome P450 2E1enzyme
DB00593EthosuximideCytochrome P450 3A43enzyme
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M1target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M3target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M2target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-10target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-3target
DB01090PentoliniumNeuronal acetylcholine receptor subunit beta-4target
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S rRNAtarget
DB01202LevetiracetamSynaptic vesicle glycoprotein 2Atarget
DB01202LevetiracetamMultidrug resistance protein 1transporter
DB01202LevetiracetamCanalicular multispecific organic anion transporter 1transporter
DB01202LevetiracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB01202LevetiracetamCytochrome P450 3A4enzyme
DB01244BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB01244BepridilSodium/potassium-transporting ATPase subunit alpha-1target
DB01244BepridilPotassium voltage-gated channel subfamily KQT member 1target
DB01244BepridilTroponin C, slow skeletal and cardiac musclestarget
DB01244BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01244BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01244BepridilMultidrug resistance protein 1transporter
DB01244BepridilCytochrome P450 2D6enzyme
DB01244BepridilPotassium voltage-gated channel subfamily H member 2target
DB01244BepridilCytochrome P450 3A4enzyme
DB01627Lincomycin50S ribosomal protein L10target
DB01954RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01954RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB02492GhavamiolAlpha-mannosidase 2target
DB02852Domoic AcidGlutamate receptor ionotropic, kainate 2target
DB03088Pidolic AcidAlpha-amylase 2Btarget
DB03088Pidolic AcidAngiogenintarget
DB03088Pidolic AcidChondroitinase-Btarget
DB03088Pidolic AcidAlpha-amylase 1target
DB03088Pidolic AcidVascular endothelial growth factor Atarget
DB03088Pidolic AcidPancreatic alpha-amylasetarget
DB03088Pidolic AcidIg lambda-1 chain C regionstarget
DB03088Pidolic AcidIg lambda chain V-II region MGCtarget
DB03088Pidolic AcidTrefoil factor 2target
DB03088Pidolic AcidCytochrome c2target
DB03088Pidolic AcidDisintegrin and metalloproteinase domain-containing protein 28target
DB03088Pidolic AcidEndo-1,4-beta-xylanasetarget
DB03088Pidolic AcidDissimilatory copper-containing nitrite reductasetarget
DB03088Pidolic AcidKeratin-associated protein 5-2target
DB03088Pidolic AcidOrexintarget
DB03088Pidolic AcidC-C motif chemokine 8target
DB03088Pidolic AcidCytochrome c'target
DB03088Pidolic AcidPancreatic alpha-amylaseenzyme
DB04599Aniracetam5-hydroxytryptamine receptor 2Atarget
DB04599AniracetamD(2) dopamine receptortarget
DB04599AniracetamGlutamate receptor 2target
DB04599AniracetamGlutamate receptor 3target
DB05102RupintrivirGenome polyproteintarget
DB05246MethsuximideCytochrome P450 2C19enzyme
DB05246MethsuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB05541BrivaracetamSynaptic vesicle glycoprotein 2Atarget
DB05541BrivaracetamSodium channel proteintarget
DB05541BrivaracetamCytochrome P450 3A4enzyme
DB05541BrivaracetamCytochrome P450 2C19enzyme
DB05541BrivaracetamCytochrome P450 2B6enzyme
DB05541BrivaracetamCytochrome P450 2C9enzyme
DB06817RaltegravirUDP-glucuronosyltransferase 1-1enzyme
DB07374Anisomycin60S ribosomal protein L10-liketarget
DB07374Anisomycin60S ribosomal protein L13atarget
DB07374Anisomycin60S ribosomal protein L23target
DB07374Anisomycin60S ribosomal protein L15target
DB07374Anisomycin60S ribosomal protein L19target
DB07374Anisomycin60S ribosomal protein L23atarget
DB07374AnisomycinProbable ribosome biogenesis protein RLP24target
DB07374Anisomycin60S ribosomal protein L26-like 1target
DB07374Anisomycin60S ribosomal protein L8target
DB07374Anisomycin60S ribosomal protein L37target
DB07374Anisomycin60S ribosomal protein L3target
DB07374Anisomycin60S ribosomal protein L11target
DB07374AnisomycinNHP2-like protein 1target
DB12200TivantinibHepatocyte growth factor receptortarget
DB05885SeletracetamSynaptic vesicle glycoprotein 2Atarget
DB05885SeletracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB05885SeletracetamGlycine receptor (alpha-1/beta)target
DB05885SeletracetamCytochrome P450 3A4enzyme