Organic compounds containing a carbonyl group =C=O bonded to two hydrocarbon groups.
DrugDrug NameDrug Description
DB00310ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
DB00323TolcaponeA catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease.
DB00333MethadoneAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
DB00348NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
DB00450DroperidolA butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.
DB00461NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
DB00502HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
DB00645DyclonineAn topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters.
DB00963BromfenacAn NSAID used to treat postoperative pain and inflammation of the eye.
DB01039FenofibrateA peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia.
DB01156BupropionA norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
DB01182PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
DB01227LevacetylmethadolFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
DB01428OxybenzoneA sunscreen agent found in sunscreens that absorbs UV rays.
DB01433Methadyl acetateUsed mainly in the treatment of narcotic dependence.
DB01491DipipanoneNot Available
DB01555AlphacetylmethadolA narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]
DB01744CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
DB01762Acetoacetic AcidNot Available
DB01878BenzophenoneAn ingredient used in sunscreens to absorb UV radiation.
DB02060CyclohexanoneCyclohexanone (also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane) is a six-carbon cyclic molecule with a ketone functional group. It is a colorless, oily liquid with an...
DB02851ThiocamphorNot Available
DB02922Hexafluoroacetone HydrateNot Available
DB040944-Hydroxy-2-ButanoneNot Available
DB04619AcetophenoneNot Available
DB04795ThenoyltrifluoroacetoneThenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.
DB05003ImexonInvestigated for use/treatment in melanoma, multiple myeloma, ovarian cancer, pancreatic cancer, and solid tumors.
DB05187ElafibranorInvestigated for use/treatment in atherosclerosis and diabetes mellitus type 2.
DB05197SofalconeInvestigated for use/treatment in gastroenteritis and ulcers.
DB06264TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
DB08990EprazinoneEprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.
DB08992EperisoneEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression...
DB09224MelperoneFor the treatment of schizophrenia, sleep, disorders, agitation and mentally confused states [L1317, L1319, L1322].
DB09286PipamperoneTreatment of chronic psychoses and states of aggressiveness of various origins .
DB09495AvobenzoneA sunscreen agent found in sunscreens that absorbs UV rays.
DB11179ExametazimeExametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection. It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex....
DB11185SulisobenzoneAn ingredient used in sunscreen to block UVA and UVB radiation.
DB11219EnzacameneAn ingredient used in sunscreen to block UVB radiation.
DB11221DioxybenzoneA benzophenone derivative used in sunscreens to block UVB and short-wave UVA radiation.
DB11269Diethylamino hydroxybenzoyl hexyl benzoateIndicated for use as a sunscreen agent.
DB11376AzaperoneAzaperone is a pyridinylpiperazine and butyrophenone agent that is capable of eliciting neuroleptic sedative and antiemetic effects. It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs...
DB11549TiletamineThis drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt...
DB11609NormethadoneAn opioid antitussive used to treat a cough associated with inflamed mucosa.
DB11742EbastineEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
DB11790RadafaxineRadafaxine has been used in trials studying the treatment of Depressive Disorder, Major.
DB12401BromperidolBromperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
DB12618ApocyninAcetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary Disease.
DB12867BenperidolBenperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
DB13016LY-2300559Ly2300559 has been used in trials studying the prevention of Migraine Headache.
DB13398OxyfedrineNot Annotated
DB13552TrifluperidolNot Annotated
DB13554MoperoneNot Annotated
DB13558MorclofoneNot Annotated
DB13567DesaspidinNot Annotated
DB13665FluanisoneNot Annotated
DB13845EtafenoneEtafenone is a vasodilator.
DB13873Fenofibric acidA fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia.
DB14020BenzoinNo approved therapeutic indications.
DB14122DihydroxymethoxychalconeCardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human...
DB032852',4,4'-TrihydroxychalconeNot Available
DB14849NebicaponeNebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of...
DB15339MethcathinoneMethcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology).
DB15359XanthohumolXanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).
DB15198DextromethadoneDextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients With Chronic Pain).
DrugDrug NameTargetType
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00310ChlorthalidoneSerum albumincarrier
DB00310ChlorthalidoneCarbonic anhydrase 1target
DB00323TolcaponeCatechol O-methyltransferasetarget
DB00323TolcaponeCytochrome P450 2C9enzyme
DB00333MethadoneNMDA receptortarget
DB00333MethadoneMu-type opioid receptortarget
DB00333MethadoneCytochrome P450 2B6enzyme
DB00333MethadoneCytochrome P450 3A4enzyme
DB00333MethadoneCytochrome P450 2C19enzyme
DB00333MethadoneDelta-type opioid receptortarget
DB00333MethadoneCytochrome P450 3A7enzyme
DB00333MethadoneCytochrome P450 2D6enzyme
DB00333MethadoneP-glycoprotein 1transporter
DB00333MethadoneCytochrome P450 2C8enzyme
DB00333MethadoneCytochrome P450 19A1enzyme
DB00333MethadoneCytochrome P450 1A2enzyme
DB00333MethadoneCytochrome P450 2C18enzyme
DB00333MethadoneCytochrome P450 2C9enzyme
DB00333Methadone5-hydroxytryptamine receptor 3Atarget
DB00333MethadoneAlpha-1-acid glycoprotein 1carrier
DB00333MethadoneSerum albumincarrier
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-7target
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-3target
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-4target
DB00333MethadoneNeuronal acetylcholine receptor subunit beta-2target
DB00348Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
DB00450DroperidolDopamine D2 receptortarget
DB00450DroperidolAlpha-1A adrenergic receptortarget
DB00461NabumetoneProstaglandin G/H synthase 1target
DB00461NabumetoneProstaglandin G/H synthase 2target
DB00461NabumetoneMyeloperoxidaseenzyme
DB00461NabumetoneCytochrome P450 1A2enzyme
DB00461NabumetoneCytochrome P450 2C9enzyme
DB00461NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00461NabumetoneAldo-keto reductase family 1 member C1enzyme
DB00461NabumetoneAldo-keto reductase family 1 member C2enzyme
DB00461NabumetoneAldo-keto reductase family 1 member C4enzyme
DB00461NabumetoneSerum albumincarrier
DB00502HaloperidolDopamine D2 receptortarget
DB00502HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
DB00502HaloperidolDopamine D1 receptortarget
DB00502HaloperidolCytochrome P450 1A2enzyme
DB00502HaloperidolCytochrome P450 2D6enzyme
DB00502Haloperidol5-hydroxytryptamine receptor 2Atarget
DB00502HaloperidolDopamine D3 receptortarget
DB00502HaloperidolCytochrome P450 3A4enzyme
DB00502HaloperidolCytochrome P450 3A5enzyme
DB00502HaloperidolCytochrome P450 3A7enzyme
DB00502HaloperidolP-glycoprotein 1transporter
DB00502HaloperidolCarbonyl reductase [NADPH] 1enzyme
DB00502HaloperidolUDP-glucuronosyltransferase 1-9enzyme
DB00502HaloperidolCytochrome P450 2C19enzyme
DB00502HaloperidolCytochrome P450 2C9enzyme
DB00502HaloperidolMelanin-concentrating hormone receptor 1target
DB00502HaloperidolSynaptic vesicular amine transportertarget
DB00502Haloperidol5-hydroxytryptamine receptor 2Ctarget
DB00502HaloperidolSigma non-opioid intracellular receptor 1target
DB00502HaloperidolHistamine H1 receptortarget
DB00502HaloperidolMuscarinic acetylcholine receptor M3target
DB00502HaloperidolAlpha-1A adrenergic receptortarget
DB00502HaloperidolAlpha-2A adrenergic receptortarget
DB00502HaloperidolAlpha-2B adrenergic receptortarget
DB00502HaloperidolAlpha-2C adrenergic receptortarget
DB00502Haloperidol5-hydroxytryptamine receptor 1Atarget
DB00502Haloperidol5-hydroxytryptamine receptor 6target
DB00502Haloperidol5-hydroxytryptamine receptor 7target
DB00502HaloperidolCytochrome P450 1A1enzyme
DB00645DyclonineSodium channel protein type 10 subunit alphatarget
DB00963BromfenacProstaglandin G/H synthase 1target
DB00963BromfenacProstaglandin G/H synthase 2target
DB00963BromfenacProstaglandin G/H synthase 2enzyme
DB01039FenofibratePeroxisome proliferator-activated receptor alphatarget
DB01039FenofibrateMatrix metalloproteinase-25target
DB01039FenofibrateCytochrome P450 2C8enzyme
DB01039FenofibrateCytochrome P450 2C9enzyme
DB01039FenofibrateNuclear receptor subfamily 1 group I member 2target
DB01039FenofibrateUDP-glucuronosyltransferase 1-9enzyme
DB01039FenofibrateBile salt export pumptransporter
DB01039FenofibrateSerum albumincarrier
DB01039FenofibrateCytochrome P450 2C19enzyme
DB01039FenofibrateCytochrome P450 2A6enzyme
DB01039FenofibrateLiver carboxylesterase 1enzyme
DB01039FenofibrateCarbonyl reductase [NADPH] 1enzyme
DB01039FenofibrateAldo-keto reductase family 1 member C1enzyme
DB01039FenofibrateAldo-keto reductase family 1 member C2enzyme
DB01039FenofibrateAldo-keto reductase family 1 member C3enzyme
DB01039FenofibrateAldose reductaseenzyme
DB01156BupropionSodium-dependent dopamine transportertarget
DB01156BupropionSodium-dependent noradrenaline transportertarget
DB01156BupropionCytochrome P450 2B6enzyme
DB01156BupropionCytochrome P450 2D6enzyme
DB01156BupropionAlpha-1-acid glycoprotein 1carrier
DB01156BupropionNeuronal acetylcholine receptor subunit alpha-3target
DB01156BupropionCytochrome P450 2C9enzyme
DB01156BupropionCytochrome P450 2E1enzyme
DB01156BupropionSolute carrier family 22 member 2transporter
DB01156Bupropion5-hydroxytryptamine receptor 3Atarget
DB01182PropafenoneSodium channel protein type 5 subunit alphatarget
DB01182PropafenonePotassium voltage-gated channel subfamily H member 2target
DB01182PropafenoneCytochrome P450 1A2enzyme
DB01182PropafenoneCytochrome P450 2D6enzyme
DB01182PropafenoneCytochrome P450 3A4enzyme
DB01182PropafenoneP-glycoprotein 1transporter
DB01182PropafenoneBeta-1 adrenergic receptortarget
DB01182PropafenoneBeta-2 adrenergic receptortarget
DB01227LevacetylmethadolMu-type opioid receptortarget
DB01227LevacetylmethadolCytochrome P450 3A4enzyme
DB01227LevacetylmethadolNeuronal acetylcholine receptor subunit beta-4target
DB01227LevacetylmethadolNeuronal acetylcholine receptor subunit alpha-3target
DB01227LevacetylmethadolCytochrome P450 3A5enzyme
DB01227LevacetylmethadolCytochrome P450 3A7enzyme
DB01428OxybenzoneProgesterone receptortarget
DB01428OxybenzoneAndrogen receptortarget
DB01428OxybenzoneEstrogen receptor alphatarget
DB01428OxybenzoneEstrogen receptor betatarget
DB01433Methadyl acetateMu-type opioid receptortarget
DB01744CamphorCamphor 5-monooxygenasetarget
DB01744CamphorTransient receptor potential cation channel subfamily V member 1target
DB01744CamphorTransient receptor potential cation channel subfamily V member 3target
DB01744CamphorTransient receptor potential cation channel subfamily A member 1target
DB01744CamphorTransient receptor potential cation channel subfamily M member 8target
DB01762Acetoacetic AcidFumarylacetoacetasetarget
DB01762Acetoacetic AcidMonocarboxylate transporter 2transporter
DB01762Acetoacetic AcidMonocarboxylate transporter 1transporter
DB01762Acetoacetic AcidMonocarboxylate transporter 4transporter
DB01762Acetoacetic AcidSodium-coupled monocarboxylate transporter 1transporter
DB01878BenzophenoneEstrogen receptor alphatarget
DB01878BenzophenoneEstrogen receptor betatarget
DB02060CyclohexanonePentaerythritol tetranitrate reductasetarget
DB02851ThiocamphorCamphor 5-monooxygenasetarget
DB040944-Hydroxy-2-ButanonePeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB04619AcetophenoneR-specific alcohol dehydrogenasetarget
DB04795ThenoyltrifluoroacetoneLiver carboxylesterase 1target
DB04795ThenoyltrifluoroacetoneSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
DB05003ImexonRibonucleoside-diphosphate reductase subunit M2target
DB05003ImexonRibonucleoside-diphosphate reductase large subunittarget
DB05187ElafibranorPeroxisome proliferator-activated receptor alphatarget
DB05187ElafibranorPeroxisome proliferator-activated receptor deltatarget
DB05187ElafibranorPeroxisome proliferator-activated receptor gammatarget
DB05197SofalconeCarbonyl reductase [NADPH] 1enzyme
DB06264TolperisoneCytochrome P450 1A2enzyme
DB08992EperisoneCytochrome P450 3A4enzyme
DB09224MelperoneDopamine D2 receptortarget
DB09224MelperoneCytochrome P450 2D6enzyme
DB09286PipamperoneDopamine D2 receptortarget
DB09286Pipamperone5-hydroxytryptamine receptor 2Atarget
DB09286PipamperoneAlpha-1 adrenergic receptorstarget
DB09286PipamperoneDopamine D4 receptortarget
DB09286PipamperoneDopamine D1 receptortarget
DB09286PipamperoneDopamine D3 receptortarget
DB09286Pipamperone5-hydroxytryptamine receptor 2Btarget
DB09286PipamperoneAlpha-2A adrenergic receptortarget
DB11185SulisobenzoneSkin epithelial cellstarget
DB11219EnzacameneProgesterone receptortarget
DB11219EnzacameneAndrogen receptortarget
DB11219EnzacameneEstrogen receptor betatarget
DB11219EnzacameneEstrogen receptor alphatarget
DB11221DioxybenzoneSex hormone-binding globulintarget
DB11221DioxybenzoneAlpha-fetoproteincarrier
DB11742EbastineCytochrome P450 3A4enzyme
DB13873Fenofibric acidPeroxisome proliferator-activated receptor alphatarget
DB13873Fenofibric acidMatrix metalloproteinase-25target
DB13873Fenofibric acidPeroxisome proliferator-activated receptor gammatarget
DB13873Fenofibric acidPeroxisome proliferator-activated receptor deltatarget
DB13873Fenofibric acidNuclear receptor subfamily 1 group I member 2target