Name
Ketones
Accession Number
DBCAT000720
Description

Organic compounds containing a carbonyl group =C=O bonded to two hydrocarbon groups.

Drugs
DrugDrug Description
ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
TolcaponeA catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease.
MethadoneAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
DroperidolA butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.
NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
DyclonineAn topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters.
BromfenacAn NSAID used to treat postoperative pain and inflammation of the eye.
FenofibrateA peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia.
BupropionA norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
LevacetylmethadolFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
OxybenzoneA sunscreen agent found in sunscreens that absorbs UV rays.
Methadyl acetateUsed mainly in the treatment of narcotic dependence.
DipipanoneNot Available
AlphacetylmethadolA narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]
CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
Acetoacetic acidNot Available
BenzophenoneAn ingredient used in sunscreens to absorb UV radiation.
CyclohexanoneCyclohexanone (also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane) is a six-carbon cyclic molecule with a ketone functional group. It is a colorless, oily liquid with an...
ThiocamphorNot Available
Hexafluoroacetone HydrateNot Available
4-hydroxybutan-2-oneNot Available
AcetophenoneNot Available
ThenoyltrifluoroacetoneThenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.
ImexonInvestigated for use/treatment in melanoma, multiple myeloma, ovarian cancer, pancreatic cancer, and solid tumors.
ElafibranorInvestigated for use/treatment in atherosclerosis and diabetes mellitus type 2.
SofalconeInvestigated for use/treatment in gastroenteritis and ulcers.
TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
EprazinoneEprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.
EperisoneEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression...
MelperoneFor the treatment of schizophrenia, sleep, disorders, agitation and mentally confused states [L1317, L1319, L1322].
PipamperoneTreatment of chronic psychoses and states of aggressiveness of various origins .
AvobenzoneA sunscreen agent found in sunscreens that absorbs UV rays.
ExametazimeExametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection. It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex....
SulisobenzoneAn ingredient used in sunscreen to block UVA and UVB radiation.
EnzacameneAn ingredient used in sunscreen to block UVB radiation.
DioxybenzoneA benzophenone derivative used in sunscreens to block UVB and short-wave UVA radiation.
Diethylamino hydroxybenzoyl hexyl benzoateIndicated for use as a sunscreen agent.
AzaperoneAzaperone is a pyridinylpiperazine and butyrophenone agent that is capable of eliciting neuroleptic sedative and antiemetic effects. It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs...
TiletamineThis drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt...
NormethadoneAn opioid antitussive used to treat a cough associated with inflamed mucosa.
EbastineEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
RadafaxineRadafaxine has been used in trials studying the treatment of Depressive Disorder, Major.
BromperidolBromperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
ApocyninAcetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary Disease.
BenperidolBenperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
LY-2300559Ly2300559 has been used in trials studying the prevention of Migraine Headache.
OxyfedrineNot Annotated
TrifluperidolNot Annotated
MoperoneNot Annotated
MorclofoneNot Annotated
DesaspidinNot Annotated
FluanisoneNot Annotated
EtafenoneEtafenone is a vasodilator.
Fenofibric acidA fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia.
BenzoinNo approved therapeutic indications.
DihydroxymethoxychalconeCardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human...
IsoliquiritigeninIsoliquiritigenin is a precursor to several flavonones in many plants.
NebicaponeNebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of...
MethcathinoneMethcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology).
XanthohumolXanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).
DextromethadoneDextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients With Chronic Pain).
PhloretinPhloretin is a natural dihydrochalcone found in apples and many other fruits.
p-Benzoyl-L-phenylalanineNot Available
R-95845R-95845 is an inhibitor of HIV-1 reverse transcriptase.
Drugs & Drug Targets
DrugTargetType
ChlorthalidoneSolute carrier family 12 member 1target
ChlorthalidoneSerum albumincarrier
ChlorthalidoneCarbonic anhydrase 1target
TolcaponeCatechol O-methyltransferasetarget
TolcaponeCytochrome P450 2C9enzyme
MethadoneNMDA receptortarget
MethadoneMu-type opioid receptortarget
MethadoneCytochrome P450 2B6enzyme
MethadoneCytochrome P450 3A4enzyme
MethadoneCytochrome P450 2C19enzyme
MethadoneDelta-type opioid receptortarget
MethadoneCytochrome P450 3A7enzyme
MethadoneCytochrome P450 2D6enzyme
MethadoneP-glycoprotein 1transporter
MethadoneCytochrome P450 2C8enzyme
MethadoneCytochrome P450 19A1enzyme
MethadoneCytochrome P450 1A2enzyme
MethadoneCytochrome P450 2C18enzyme
MethadoneCytochrome P450 2C9enzyme
Methadone5-hydroxytryptamine receptor 3Atarget
MethadoneAlpha-1-acid glycoprotein 1carrier
MethadoneSerum albumincarrier
MethadoneNeuronal acetylcholine receptor subunit alpha-7target
MethadoneNeuronal acetylcholine receptor subunit alpha-3target
MethadoneNeuronal acetylcholine receptor subunit alpha-4target
MethadoneNeuronal acetylcholine receptor subunit beta-2target
Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
DroperidolDopamine D2 receptortarget
DroperidolAlpha-1A adrenergic receptortarget
NabumetoneProstaglandin G/H synthase 1target
NabumetoneProstaglandin G/H synthase 2target
NabumetoneMyeloperoxidaseenzyme
NabumetoneCytochrome P450 1A2enzyme
NabumetoneCytochrome P450 2C9enzyme
NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
NabumetoneAldo-keto reductase family 1 member C1enzyme
NabumetoneAldo-keto reductase family 1 member C2enzyme
NabumetoneAldo-keto reductase family 1 member C4enzyme
NabumetoneSerum albumincarrier
HaloperidolDopamine D2 receptortarget
HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
HaloperidolDopamine D1 receptortarget
HaloperidolCytochrome P450 1A2enzyme
HaloperidolCytochrome P450 2D6enzyme
Haloperidol5-hydroxytryptamine receptor 2Atarget
HaloperidolDopamine D3 receptortarget
HaloperidolCytochrome P450 3A4enzyme
HaloperidolCytochrome P450 3A5enzyme
HaloperidolCytochrome P450 3A7enzyme
HaloperidolP-glycoprotein 1transporter
HaloperidolCarbonyl reductase [NADPH] 1enzyme
HaloperidolUDP-glucuronosyltransferase 1-9enzyme
HaloperidolCytochrome P450 2C19enzyme
HaloperidolCytochrome P450 2C9enzyme
HaloperidolMelanin-concentrating hormone receptor 1target
HaloperidolSynaptic vesicular amine transportertarget
Haloperidol5-hydroxytryptamine receptor 2Ctarget
HaloperidolSigma non-opioid intracellular receptor 1target
HaloperidolHistamine H1 receptortarget
HaloperidolMuscarinic acetylcholine receptor M3target
HaloperidolAlpha-1A adrenergic receptortarget
HaloperidolAlpha-2A adrenergic receptortarget
HaloperidolAlpha-2B adrenergic receptortarget
HaloperidolAlpha-2C adrenergic receptortarget
Haloperidol5-hydroxytryptamine receptor 1Atarget
Haloperidol5-hydroxytryptamine receptor 6target
Haloperidol5-hydroxytryptamine receptor 7target
HaloperidolCytochrome P450 1A1enzyme
DyclonineSodium channel protein type 10 subunit alphatarget
BromfenacProstaglandin G/H synthase 1target
BromfenacProstaglandin G/H synthase 2target
BromfenacProstaglandin G/H synthase 2enzyme
FenofibratePeroxisome proliferator-activated receptor alphatarget
FenofibrateMatrix metalloproteinase-25target
FenofibrateCytochrome P450 2C8enzyme
FenofibrateCytochrome P450 2C9enzyme
FenofibrateNuclear receptor subfamily 1 group I member 2target
FenofibrateUDP-glucuronosyltransferase 1-9enzyme
FenofibrateBile salt export pumptransporter
FenofibrateSerum albumincarrier
FenofibrateCytochrome P450 2C19enzyme
FenofibrateCytochrome P450 2A6enzyme
FenofibrateLiver carboxylesterase 1enzyme
FenofibrateCarbonyl reductase [NADPH] 1enzyme
FenofibrateAldo-keto reductase family 1 member C1enzyme
FenofibrateAldo-keto reductase family 1 member C2enzyme
FenofibrateAldo-keto reductase family 1 member C3enzyme
FenofibrateAldose reductaseenzyme
BupropionSodium-dependent dopamine transportertarget
BupropionSodium-dependent noradrenaline transportertarget
BupropionCytochrome P450 2B6enzyme
BupropionCytochrome P450 2D6enzyme
BupropionAlpha-1-acid glycoprotein 1carrier
BupropionNeuronal acetylcholine receptor subunit alpha-3target
BupropionCytochrome P450 2C9enzyme
BupropionCytochrome P450 2E1enzyme
BupropionSolute carrier family 22 member 2transporter
Bupropion5-hydroxytryptamine receptor 3Atarget
PropafenoneSodium channel protein type 5 subunit alphatarget
PropafenonePotassium voltage-gated channel subfamily H member 2target
PropafenoneCytochrome P450 1A2enzyme
PropafenoneCytochrome P450 2D6enzyme
PropafenoneCytochrome P450 3A4enzyme
PropafenoneP-glycoprotein 1transporter
PropafenoneBeta-1 adrenergic receptortarget
PropafenoneBeta-2 adrenergic receptortarget
LevacetylmethadolMu-type opioid receptortarget
LevacetylmethadolCytochrome P450 3A4enzyme
LevacetylmethadolNeuronal acetylcholine receptor subunit beta-4target
LevacetylmethadolNeuronal acetylcholine receptor subunit alpha-3target
LevacetylmethadolCytochrome P450 3A5enzyme
LevacetylmethadolCytochrome P450 3A7enzyme
OxybenzoneProgesterone receptortarget
OxybenzoneAndrogen receptortarget
OxybenzoneEstrogen receptor alphatarget
OxybenzoneEstrogen receptor betatarget
Methadyl acetateMu-type opioid receptortarget
CamphorCamphor 5-monooxygenasetarget
CamphorTransient receptor potential cation channel subfamily V member 1target
CamphorTransient receptor potential cation channel subfamily V member 3target
CamphorTransient receptor potential cation channel subfamily A member 1target
CamphorTransient receptor potential cation channel subfamily M member 8target
Acetoacetic acidFumarylacetoacetasetarget
Acetoacetic acidMonocarboxylate transporter 2transporter
Acetoacetic acidMonocarboxylate transporter 1transporter
Acetoacetic acidMonocarboxylate transporter 4transporter
Acetoacetic acidSodium-coupled monocarboxylate transporter 1transporter
BenzophenoneEstrogen receptor alphatarget
BenzophenoneEstrogen receptor betatarget
CyclohexanonePentaerythritol tetranitrate reductasetarget
ThiocamphorCamphor 5-monooxygenasetarget
4-hydroxybutan-2-onePeptidyl-prolyl cis-trans isomerase FKBP1Atarget
AcetophenoneR-specific alcohol dehydrogenasetarget
ThenoyltrifluoroacetoneLiver carboxylesterase 1target
ThenoyltrifluoroacetoneSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
ImexonRibonucleoside-diphosphate reductase subunit M2target
ImexonRibonucleoside-diphosphate reductase large subunittarget
ElafibranorPeroxisome proliferator-activated receptor alphatarget
ElafibranorPeroxisome proliferator-activated receptor deltatarget
ElafibranorPeroxisome proliferator-activated receptor gammatarget
SofalconeCarbonyl reductase [NADPH] 1enzyme
TolperisoneCytochrome P450 1A2enzyme
EperisoneCytochrome P450 3A4enzyme
MelperoneDopamine D2 receptortarget
MelperoneCytochrome P450 2D6enzyme
PipamperoneDopamine D2 receptortarget
Pipamperone5-hydroxytryptamine receptor 2Atarget
PipamperoneAlpha-1 adrenergic receptorstarget
PipamperoneDopamine D4 receptortarget
PipamperoneDopamine D1 receptortarget
PipamperoneDopamine D3 receptortarget
Pipamperone5-hydroxytryptamine receptor 2Btarget
PipamperoneAlpha-2A adrenergic receptortarget
SulisobenzoneSkin epithelial cellstarget
EnzacameneProgesterone receptortarget
EnzacameneAndrogen receptortarget
EnzacameneEstrogen receptor betatarget
EnzacameneEstrogen receptor alphatarget
DioxybenzoneSex hormone-binding globulintarget
DioxybenzoneAlpha-fetoproteincarrier
EbastineCytochrome P450 3A4enzyme
Fenofibric acidPeroxisome proliferator-activated receptor alphatarget
Fenofibric acidMatrix metalloproteinase-25target
Fenofibric acidPeroxisome proliferator-activated receptor gammatarget
Fenofibric acidPeroxisome proliferator-activated receptor deltatarget
Fenofibric acidNuclear receptor subfamily 1 group I member 2target
PhloretinHTH-type transcriptional regulator TtgRtarget
p-Benzoyl-L-phenylalanineTyrosine-protein phosphatase non-receptor type 1target
p-Benzoyl-L-phenylalanineTyrosine--tRNA ligase, cytoplasmictarget
R-95845Gag-Pol polyproteintarget
R-95845Gag-Pol polyproteintarget