|DB00310||Chlorthalidone||Chlorthalidone is indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.
Chlorthalidone is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
Chlorthalidone has also been found useful in edema due to various forms of renal dysfunction, such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.|
|DB00323||Tolcapone||Used as an adjunct to levodopa/carbidopa therapy for the symptomatic treatment of Parkinson's Disease. This drug is generally reserved for patients with parkinsonian syndrome receiving levodopa/carbidopa who are experiencing symptom fluctuations and are not responding adequately to or are not candidates for other adjunctive therapies.|
|DB00333||Methadone||For the treatment of dry cough, drug withdrawal syndrome, opioid type drug dependence, and pain.|
|DB00348||Nitisinone||Used as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1.|
|DB00450||Droperidol||Droperidol is ssed to produce tranquilization and to reduce the incidence of nausea and vomiting in surgical and diagnostic procedures.|
1) Symptomatic relief in rheumatoid arthritis.
2) Symptomatic relief in osteoarthritis.|
|DB00502||Haloperidol||Haloperidol is indicated for a number of conditions including for the treatment of schizophrenia, for the manifestations of psychotic disorders, for the control of tics and vocal utterances of Tourette’s Disorder in children and adults, for treatment of severe behavior problems in children of combative, explosive hyperexcitability (which cannot be accounted for by immediate provocation). Haloperidol is also indicated in the short-term treatment of hyperactive children who show excessive motor activity with accompanying conduct disorders consisting of some or all of the following symptoms: impulsivity, difficulty sustaining attention, aggressivity, mood lability, and poor frustration tolerance. Haloperidol tablets should be reserved for these two groups of children only after failure to respond to psychotherapy or medications other than antipsychotics.[F4645]|
|DB00645||Dyclonine||Used to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the esophagus, larynx, mouth, pharynx or throat, respiratory tract or trachea, urinary tract, or vagina. Also used to suppress the gag reflex and/or other laryngeal and esophageal reflexes to facilitate dental examination or procedures (including oral surgery), endoscopy, or intubation. Also used for relief of canker sores, cold sores or fever blister.|
|DB00963||Bromfenac||For the treatment of postoperative inflammation in patients who have undergone cataract extraction.|
|DB01039||Fenofibrate||For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)|
|DB01156||Bupropion||Bupropion is indicated for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
When used in combination with [naltrexone] as the marketed product ContraveⓇ, bupropion is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of:
•30 kg/m^2 or greater (obese) or
•27 kg/m^2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).
Bupropion is also used off-label as a first-line treatment in patients with ADHD and comorbid bipolar disorder when used as an adjunct to mood stabilizers.[F4624]|
|DB01182||Propafenone||Used to prolong the time to recurrence of paroxysmal atrial fibrillation/flutter (PAF) associated with disabling symptoms in patients without structural heart disease. Also used for the treatment of life-threatening documented ventricular arrhythmias, such as sustained ventricular tachycardia.|
|DB01227||Levacetylmethadol||For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.|
|DB01428||Oxybenzone||Used as an ingredient in sunscreen and other cosmetics.|
|DB01433||Methadyl acetate||Used mainly in the treatment of narcotic dependence.|
|DB01762||Acetoacetic Acid||Not Available|
|DB02922||Hexafluoroacetone Hydrate||Not Available|
|DB05003||Imexon||Investigated for use/treatment in melanoma, multiple myeloma, ovarian cancer, pancreatic cancer, and solid tumors.|
|DB05187||Elafibranor||Investigated for use/treatment in atherosclerosis and diabetes mellitus type 2.|
|DB05197||Sofalcone||Investigated for use/treatment in gastroenteritis and ulcers.|
|DB06264||Tolperisone||Investigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.|
|DB09224||Melperone||For the treatment of schizophrenia, sleep, disorders, agitation and mentally confused states [L1317, L1319, L1322]. |
|DB09286||Pipamperone||Treatment of chronic psychoses and states of aggressiveness of various origins [L1515].|
|DB09495||Avobenzone||Sun protection factor, added in the sunscreen products for its wide spectrum ultraviolet absorption properties. |
|DB11185||Sulisobenzone||Sunscreening agents are used to prevent sunburn, actinic keratosis, and premature skin aging and to reduce the incidence of skin cancer [L2664].|
|DB11219||Enzacamene||Indicated for use as an active sunscreen agent. |
|DB11221||Dioxybenzone||Indicated for use as an active sunscreen agent. |
|DB11269||Diethylamino hydroxybenzoyl hexyl benzoate||Indicated for use as a sunscreen agent. |
|DB11609||Normethadone||For use in the treatment of cough when other less potent treatments have failed [FDA Label].|
|DB13873||Fenofibric acid||For use as an adjunctive therapy to diet to: (a) reduce triglyceride levels in adult patients with severe hypertriglyceridemia, and (b) reduce elevated total cholesterol, low-density-lipoprotein (LDL-C), triglycerides, and apolipoprotein B, and to increase high-density-lipoprotein (HDL-C) in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). [FDA Label]|
|DB14020||Benzoin||No approved therapeutic indications. |