Steroids, Fluorinated

Name
Steroids, Fluorinated
Accession Number
DBCAT000749
Description

Steroids which are substituted with one or more fluorine atoms in any position.

Drugs
DrugDrug Description
FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
DiflorasoneA topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort.
AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
DesoximetasoneA glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
UlobetasolA lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
FlumethasoneA corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
ClocortoloneA corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp.
FlurandrenolideA corticosteroid used to treat corticosteroid-responsive dermatoses.
Clobetasol propionateA corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis.
FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
FluoxymesteroneA synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
ParamethasoneFor the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
DifluprednateA topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.
FluocortoloneFluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
FluprednisoloneA synthetic glucocorticoid with anti-inflammatory properties.
Dexamethasone isonicotinateDexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
IsoflupredoneNot Annotated
ClobetasolClobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
FluocinoloneFluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral Lichen Planus, Macular Degeneration, and Choroidal Neovascularization.
ClobetasoneA corticosteroid used to treat dry eyes, eczema, and dermatitis.
HalometasoneNot Annotated
Isoflupredone acetateNot Annotated
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
Clocortolone acetateNot Annotated
Paramethasone acetateNot Annotated
Betamethasone phosphateA fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
Dexamethasone metasulfobenzoateAn ophthalmic and auricular corticosteroid used with antibiotics for the treatment of otitis externa, blepharitis, and other inflammatory eye conditions.
Drugs & Drug Targets
DrugTargetType
FlunisolideCorticosteroid-binding globulincarrier
FlunisolideGlucocorticoid receptortarget
FlunisolideCytochrome P450 3A4enzyme
DiflorasoneGlucocorticoid receptortarget
AmcinonideGlucocorticoid receptortarget
AmcinonideAnnexin A1target
AmcinonideCytochrome P450 3A4enzyme
AmcinonideCytochrome P450 3A5enzyme
FluorometholoneCorticosteroid-binding globulincarrier
FluorometholoneCytochrome P450 3A4enzyme
FluorometholoneGlucocorticoid receptortarget
FluorometholoneCytochrome P450 3A5enzyme
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneP-glycoprotein 1transporter
BetamethasoneCytochrome P450 19A1enzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneSerum albumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
DesoximetasoneGlucocorticoid receptortarget
Fluocinolone acetonideCorticosteroid-binding globulincarrier
Fluocinolone acetonideGlucocorticoid receptortarget
Fluocinolone acetonideCytochrome P450 3A4enzyme
Fluocinolone acetonideAnnexin A1target
Fluocinolone acetonideAnnexin A2target
Fluocinolone acetonideAnnexin A3target
Fluocinolone acetonideAnnexin A4target
Fluocinolone acetonideAnnexin A5target
UlobetasolCorticosteroid-binding globulincarrier
UlobetasolGlucocorticoid receptortarget
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneSerum albumincarrier
FlumethasoneCorticosteroid-binding globulincarrier
FlumethasoneGlucocorticoid receptortarget
FlumethasoneCytochrome P450 3A4enzyme
ClocortoloneGlucocorticoid receptortarget
FlurandrenolideCorticosteroid-binding globulincarrier
FlurandrenolideGlucocorticoid receptortarget
FlurandrenolideCytochrome P450 3A4enzyme
Clobetasol propionateGlucocorticoid receptortarget
Clobetasol propionateCytochrome P450 3A4enzyme
Clobetasol propionateCytochrome P450 3A5enzyme
Clobetasol propionateAnnexin A1target
Clobetasol propionateMineralocorticoid receptortarget
Clobetasol propionateCorticosteroid-binding globulincarrier
Clobetasol propionateSerum albumincarrier
FluocinonideCorticosteroid-binding globulincarrier
FluocinonideGlucocorticoid receptortarget
FluocinonideSmoothened homologtarget
FluocinonideCytochrome P450 3A4enzyme
FluocinonideCytochrome P450 3A5enzyme
FluoxymesteroneSex hormone-binding globulincarrier
FluoxymesteroneEstrogen receptor alphatarget
FluoxymesteroneAndrogen receptortarget
FluoxymesteroneGlucocorticoid receptortarget
FluoxymesteroneCorticosteroid 11-beta-dehydrogenase isozyme 2target
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
ParamethasoneCorticosteroid-binding globulincarrier
ParamethasoneGlucocorticoid receptortarget
ParamethasoneCytochrome P450 3A4enzyme
ParamethasoneCytochrome P450 3A5enzyme
DifluprednateGlucocorticoid receptortarget
DifluprednateCytochrome P450 3A4enzyme
FluocortoloneCytochrome P450 3A4enzyme
FluocortoloneCytochrome P450 3A5enzyme
DifluocortoloneAnnexin A3target
DifluocortoloneGlucocorticoid receptortarget
DifluocortoloneCytochrome P450 3A4enzyme
DifluocortoloneCytochrome P450 3A5enzyme
FluprednisoloneCytochrome P450 3A4enzyme
Dexamethasone isonicotinateCytochrome P450 3A4enzyme
Dexamethasone isonicotinateCytochrome P450 3A5enzyme
ClobetasolCytochrome P450 3A4enzyme
ClobetasolCytochrome P450 3A5enzyme
ClobetasoneGlucocorticoid receptortarget
ClobetasoneCytochrome P450 3A4enzyme
HalometasoneCytochrome P450 3A4enzyme
HalometasoneCytochrome P450 3A5enzyme
Dexamethasone acetateGlucocorticoid receptortarget
Dexamethasone acetateAnnexin A1target
Dexamethasone acetateNitric oxide synthase, inducibletarget
Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
Dexamethasone acetateCytochrome P450 3A4enzyme
Dexamethasone acetateCytochrome P450 3A5enzyme
Dexamethasone acetateCytochrome P450 3A7enzyme
Dexamethasone acetateBile salt export pumptransporter
Dexamethasone acetateP-glycoprotein 1transporter
Dexamethasone acetateCanalicular multispecific organic anion transporter 1transporter
Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
Dexamethasone acetateATP-binding cassette sub-family G member 2transporter
Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Dexamethasone acetateCytochrome P450 1A1enzyme
Dexamethasone acetateCytochrome P450 2A6enzyme
Dexamethasone acetateCytochrome P450 2B6enzyme
Dexamethasone acetateCytochrome P450 2C19enzyme
Dexamethasone acetateCytochrome P450 2C8enzyme
Dexamethasone acetateCytochrome P450 2E1enzyme
Dexamethasone acetateCytochrome P450 3A43enzyme
Dexamethasone acetateCytochrome P450 4A11enzyme
Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
Dexamethasone acetateSerum albumincarrier
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Dexamethasone acetateSolute carrier family 22 member 8transporter
Clocortolone acetateCytochrome P450 3A4enzyme
Clocortolone acetateCytochrome P450 3A5enzyme
Betamethasone phosphateCytochrome P450 3A4enzyme
Betamethasone phosphateCytochrome P450 3A5enzyme
Betamethasone phosphateGlucocorticoid receptortarget
Betamethasone phosphateAnnexin A1target
Betamethasone phosphateCorticosteroid-binding globulincarrier
Betamethasone phosphateSerum albumincarrier
Betamethasone phosphateSolute carrier organic anion transporter family member 1A2transporter
Betamethasone phosphateP-glycoprotein 1transporter
Betamethasone phosphateSolute carrier family 22 member 8transporter