C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
|Drug||Drug Name||Drug Indication|
|DB00390||Digoxin||Digoxin is indicated in the following conditions: 1) For the treatment of mild to moderate heart failure in adult patients.[L6775] 2) To increase myocardial contraction in children diagnosed with heart failure.[L6775] 3) To maintain control ventricular rate in adult patients diagnosed with chronic atrial fibrillation.[L6775] In adults with heart failure, when it is clinically possible, digoxin should be administered in conjunction with a diuretic and an angiotensin-converting enzyme (ACE) inhibitor for optimum effects.[L6775]|
|DB00511||Acetyldigitoxin||Used for fast digitalization in congestive heart failure.|
|DB01078||Deslanoside||For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.|
|DB01092||Ouabain||For the treatment of atrial fibrillation and flutter and heart failure|
|DB01396||Digitoxin||For the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.|
|DB13467||Lanatoside C||Not Available|