Phenylacetates

Derivatives of phenylacetic acid. Included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. Note that this class of compounds should not be confused with derivatives of phenyl acetate, which contain the PHENOL ester of ACETIC ACID.
DrugDrug NameDrug Description
DB00209TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
DB00422MethylphenidateA stimulant used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
DB00586DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00771ClidiniumA synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS.
DB00979CyclopentolateAn anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing.
DB01283LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
DB01461DimenoxadolDimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United...
DB03588Diphenylacetic AcidNot Available
DB04843MepenzolateA postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
DB06701DexmethylphenidateA norepinephrine-dopamine reuptake inhibitor used in the treatment of ADHD in conjunction with other therapies.
DB06736AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
DB09023BenactyzineBenactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. Benactyzine is no longer widely used in medicine, although it is still a...
DB12278PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
DB12408PF-03635659Pf03635659 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
DB13234PropanididAn intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
DB13351PiperidolateNot Annotated
DB13380DifemerineNot Annotated
DB13507PoldineNot Annotated
DB13542BevoniumNot Annotated
DB08327Homogentisic acidNot Available
DrugDrug NameTargetType
DB00209TrospiumMuscarinic acetylcholine receptor M1target
DB00209TrospiumCytochrome P450 2D6enzyme
DB00422MethylphenidateSodium-dependent dopamine transportertarget
DB00422MethylphenidateSodium-dependent noradrenaline transportertarget
DB00422MethylphenidateCarboxylesteraseenzyme
DB00422Methylphenidate5-hydroxytryptamine receptor 1Atarget
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00586DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DB00586DiclofenacArachidonate 5-lipoxygenaseenzyme
DB00586DiclofenacSodium channel protein type 4 subunit alphatransporter
DB00586DiclofenacAcid-sensing ion channel 1transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DB00586DiclofenacPhospholipase A2, membrane associatedenzyme
DB00771ClidiniumMuscarinic acetylcholine receptor M1target
DB00979CyclopentolateMuscarinic acetylcholine receptor M1target
DB00979CyclopentolateCholinesteraseenzyme
DB01283LumiracoxibProstaglandin G/H synthase 2target
DB01283LumiracoxibProstaglandin G/H synthase 1target
DB01283LumiracoxibCytochrome P450 2C9enzyme
DB01283LumiracoxibCytochrome P450 2C19enzyme
DB01283LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
DB01283LumiracoxibCytochrome P450 1A2enzyme
DB03588Diphenylacetic AcidCathepsin Btarget
DB04843MepenzolateMuscarinic acetylcholine receptor M1target
DB04843MepenzolateMuscarinic acetylcholine receptor M3target
DB06701DexmethylphenidateSodium-dependent dopamine transportertarget
DB06701DexmethylphenidateSodium-dependent noradrenaline transportertarget
DB06701DexmethylphenidateSodium-dependent serotonin transportertarget
DB06701DexmethylphenidateCarboxylesteraseenzyme
DB06736AceclofenacCytochrome P450 2C9enzyme
DB06736AceclofenacProstaglandin G/H synthase 2target
DB06736AceclofenacProstaglandin G/H synthase 1target
DB12278PropiverineMuscarinic acetylcholine receptor M1target
DB12278PropiverineMuscarinic acetylcholine receptor M2target
DB12278PropiverineMuscarinic acetylcholine receptor M3target
DB12278PropiverineMuscarinic acetylcholine receptor M4target
DB12278PropiverineMuscarinic acetylcholine receptor M5target
DB12278PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB12278PropiverineAlpha-1A adrenergic receptortarget
DB12278PropiverineCytochrome P450 3A4enzyme
DB12278PropiverineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB12278PropiverineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB08327Homogentisic acidPenicillin G acylasetarget