Abortifacient Agents, Nonsteroidal

Non-steroidal chemical compounds with abortifacient activity.
DrugDrug NameDrug Description
DB00429Carboprost tromethamineA prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective.
DB00563MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
DB00929MisoprostolA prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers.
DB01160Dinoprost tromethamineUsed for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities...
DB08964GemeprostIndicated for the softening and dilatation of the cervix uteri prior to transcervical, intrauterine operative procedures in the first trimester of pregnancy or facilitating therapeutic termination of pregnancy in patients...
DB11411FenprostaleneNot Annotated
DB12708SulprostoneSulprostone has been used in trials studying Abortion, Induced.
DB12789DinoprostA medication used to induce a second trimester abortion.
DrugDrug NameTargetType
DB00429Carboprost tromethamineProstaglandin E2 receptor EP1 subtypetarget
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateP-glycoprotein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DB00563MethotrexateCytochrome P450 3A4enzyme
DB00563MethotrexateThymidylate synthasetarget
DB00563MethotrexateBifunctional purine biosynthesis protein PURHtarget
DB00563MethotrexateFolate receptor betatransporter
DB00563MethotrexateSolute carrier family 15 member 1transporter
DB00563MethotrexateProton-coupled amino acid transporter 1transporter
DB00929MisoprostolProstaglandin E2 receptor EP2 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP3 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP4 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP1 subtypetarget
DB01160Dinoprost tromethamineProstacyclin receptortarget
DB01160Dinoprost tromethamineProstaglandin F2-alpha receptortarget
DB01160Dinoprost tromethamineSolute carrier family 22 member 2transporter
DB01160Dinoprost tromethamineSolute carrier family 22 member 6transporter
DB01160Dinoprost tromethamineSolute carrier family 22 member 7transporter
DB01160Dinoprost tromethamineSolute carrier family 22 member 8transporter
DB01160Dinoprost tromethamineSolute carrier family 22 member 11transporter
DB01160Dinoprost tromethamineSolute carrier organic anion transporter family member 2A1transporter
DB01160Dinoprost tromethamineSolute carrier organic anion transporter family member 3A1transporter
DB08964GemeprostProstaglandin E2 receptor EP2 subtypetarget
DB08964GemeprostProstaglandin E2 receptor EP3 subtypetarget
DB12789DinoprostProstaglandin D2 receptor 2target