Hydrocarbons, Chlorinated

Hydrocarbon compounds with one or more of the hydrogens replaced by CHLORINE.
DrugDrug NameDrug Indication
DB00431LindaneFor the treatment of patients infested with Sarcoptes scabiei or pediculosis capitis who have either failed to respond to adequate doses, or are intolerant of other approved therapies.
DB00648MitotaneFor treatment of inoperable adrenocortical tumours; Cushing's syndrome
DB00756HexachloropheneFor use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
DB019573-ChlorophenolNot Available
DB031102-ChlorophenolNot Available
DB03733Ethylene DichlorideNot Available
DB08809Dichloroacetic acidNot Available
DB09082VilanterolVilanterol is approved for use in several combination products such as with fluticasone furoate under the tradename Breo Ellipta and in combination with umeclidinium bromide as Anoro Ellipta. Approved by the FDA in 2013, use of Breo Ellipta is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.
DB11121ChloroxylenolThe predominant medical applications for which chloroxylenol is formally indicated for therapeutic use is as an application to the skin for use in cuts, bites, stings, abrasions, and for use as antiseptic hand cleaner [L1992].
DB11152TrichloroacetateNot Available
DB11387ChloroformNot Available
DB11396DichlorophenNot Available
DB11831DinitrochlorobenzeneNot Available
DB12117MitomethNot Available
DB12838TetrasulNot Available
DB13154ParachlorophenolUsed as an intermediate in organic synthesis of dyes and drugs. Local antibacterial agent in root canal therapy, as topical antiseptic in ointments
DB13259Ethyl chlorideNot Available
DB13323TrichloroethyleneNot Available
DB13424ClofenotaneNot Available
DB139631,2-dichlorobenzeneNot Available
DrugDrug NameTargetType
DB00431LindaneGamma-aminobutyric acid receptor subunit beta-1target
DB00431LindaneGlycine receptor subunit alpha-1target
DB00431LindaneGlycine receptor subunit alpha-2target
DB00431LindaneGlycine receptor subunit alpha-3target
DB00431LindaneGlycine receptor subunit betatarget
DB00431LindaneGamma-aminobutyric acid receptor subunit beta-3target
DB00431LindaneGamma-aminobutyric acid receptor subunit rho-1target
DB00431LindaneProgesterone receptortarget
DB00431LindaneEstrogen receptor alphatarget
DB00431LindaneNuclear receptor subfamily 1 group I member 2target
DB00648MitotaneCytochrome P450 11B1, mitochondrialtarget
DB00648MitotaneAdrenodoxin, mitochondrialtarget
DB00648MitotaneSex hormone-binding globulincarrier
DB00648MitotaneCorticosteroid-binding globulincarrier
DB00648MitotaneCytochrome P450 3A4enzyme
DB00648MitotaneEstrogen receptor alphatarget
DB00648MitotaneProgesterone receptortarget
DB00648MitotaneAndrogen receptortarget
DB00648MitotaneThyroxine-binding globulincarrier
DB00756HexachloropheneD-lactate dehydrogenasetarget
DB00756HexachloropheneGlutamate dehydrogenase 1, mitochondrialtarget
DB00756HexachloropheneSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialtarget
DB00756HexachloropheneEstrogen receptor alphatarget
DB031102-ChlorophenolMitogen-activated protein kinase 14target
DB03733Ethylene DichlorideHaloalkane dehalogenasetarget
DB08809Dichloroacetic acid[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrialtarget
DB08809Dichloroacetic acidMaleylacetoacetate isomerasetarget
DB09082VilanterolCytochrome P450 3A4enzyme
DB09082VilanterolBeta-2 adrenergic receptortarget
DB11831DinitrochlorobenzeneMethylated-DNA--protein-cysteine methyltransferasetarget
DB11831DinitrochlorobenzeneGlutathione S-transferase Ptarget
DB13154ParachlorophenolSolute carrier organic anion transporter family member 1B3transporter
DB13154ParachlorophenolSodium channel protein type 4 subunit alphatarget