Endothelium-Dependent Relaxing Factors

All categories
Name
Endothelium-Dependent Relaxing Factors
Accession Number
DBCAT000866
Description

Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Several factors have been identified, including NITRIC OXIDE and PROSTACYCLIN.

Drugs
DrugDrug Description
Nitric OxideA vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
Drugs & Drug Targets
DrugTargetType
Nitric OxideGuanylate cyclase soluble subunit alpha-2target
Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
Nitric OxideCytochrome P450 1A2enzyme
Nitric OxideCytochrome P450 2B6enzyme
Nitric OxideCytochrome P450 3A4enzyme
Nitric OxideMetallothionein-1Atarget
Nitric OxideIndoleamine 2,3-dioxygenase 1target
Nitric OxideNitric oxide synthase, endothelialtarget