Butyrophenones

Name
Butyrophenones
Accession Number
DBCAT000878
Description

Compounds containing phenyl-1-butanone.

Drugs
DrugDrug Description
HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
DroperidolA butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.
AzaperoneAzaperone is a pyridinylpiperazine and butyrophenone agent that is capable of eliciting neuroleptic sedative and antiemetic effects. It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs...
BromperidolBromperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
BenperidolBenperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
TrifluperidolNot Annotated
Drugs & Drug Targets
DrugTargetType
HaloperidolDopamine D2 receptortarget
HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
HaloperidolDopamine D1 receptortarget
HaloperidolCytochrome P450 1A2enzyme
HaloperidolCytochrome P450 2D6enzyme
Haloperidol5-hydroxytryptamine receptor 2Atarget
HaloperidolDopamine D3 receptortarget
HaloperidolCytochrome P450 3A4enzyme
HaloperidolCytochrome P450 3A5enzyme
HaloperidolCytochrome P450 3A7enzyme
HaloperidolP-glycoprotein 1transporter
HaloperidolCarbonyl reductase [NADPH] 1enzyme
HaloperidolUDP-glucuronosyltransferase 1-9enzyme
HaloperidolCytochrome P450 2C19enzyme
HaloperidolCytochrome P450 2C9enzyme
HaloperidolMelanin-concentrating hormone receptor 1target
HaloperidolSynaptic vesicular amine transportertarget
Haloperidol5-hydroxytryptamine receptor 2Ctarget
HaloperidolSigma non-opioid intracellular receptor 1target
HaloperidolHistamine H1 receptortarget
HaloperidolMuscarinic acetylcholine receptor M3target
HaloperidolAlpha-1A adrenergic receptortarget
HaloperidolAlpha-2A adrenergic receptortarget
HaloperidolAlpha-2B adrenergic receptortarget
HaloperidolAlpha-2C adrenergic receptortarget
Haloperidol5-hydroxytryptamine receptor 1Atarget
Haloperidol5-hydroxytryptamine receptor 6target
Haloperidol5-hydroxytryptamine receptor 7target
HaloperidolCytochrome P450 1A1enzyme
DroperidolDopamine D2 receptortarget
DroperidolAlpha-1A adrenergic receptortarget