Pyrimidine Nucleotides

Pyrimidines with a RIBOSE and phosphate attached that can polymerize to form DNA and RNA.
DrugDrug NameDrug Description
DB00475ChlordiazepoxideA benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
DB01643Thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
DB03041UDP-alpha-D-glucuronic acidA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides....
DB03326Deoxycytidylyl-3',5'-guanosineNot Available
DB03501Galactose-uridine-5'-diphosphateA nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides,...
DB037186-aza uridine 5'-monophosphateNot Available
DB03800Deoxyuridine monophosphateNot Available
DB04672Cyclic 3',5'-thymidine monophosphateNot Available
DB04983DenufosolFor use as an inhaled treatment for cystic fibrosis.
DB08934SofosbuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
DB01861Uridine diphosphate glucoseA key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and...
DB027143'-UridinemonophosphateNot Available
DB032582'-Deoxycytidine 5'-triphosphateNot Available
DB03403Cytidine-5'-MonophosphateA pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.
DB03685Uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
DB04005Uridine 5'-triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
DB12153CiticolineCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnostic of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar...
DB15057NUC-1031NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
DB019955-methylcytidine 5'-monophosphateNot Available
DB03666Zidovudine monophosphateNot Available
DB04542Zidovudine diphosphateNot Available
DB04243TMPNot Available
DrugDrug NameTargetType
DB00475ChlordiazepoxideGABA-A receptor (anion channel)target
DB01643Thymidine monophosphateThymidylate kinasetarget
DB01643Thymidine monophosphateThymidylate kinasetarget
DB01643Thymidine monophosphateThymidine kinasetarget
DB01643Thymidine monophosphateThymidylate synthasetarget
DB01643Thymidine monophosphateDNA topoisomerase 1target
DB01643Thymidine monophosphateThymidylate synthasetarget
DB01643Thymidine monophosphatePCZA361.16target
DB01643Thymidine monophosphateDNA polymerase III subunit epsilontarget
DB01643Thymidine monophosphateGlucose-1-phosphate thymidylyltransferasetarget
DB03041UDP-alpha-D-glucuronic acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3target
DB03041UDP-alpha-D-glucuronic acidUDP-glucose 6-dehydrogenasetarget
DB03041UDP-alpha-D-glucuronic acidUDP-glucose 4-epimerasetarget
DB03326Deoxycytidylyl-3',5'-guanosineRibonuclease pancreatictarget
DB03501Galactose-uridine-5'-diphosphateHisto-blood group ABO system transferasetarget
DB03501Galactose-uridine-5'-diphosphateUDP-glucose 4-epimerasetarget
DB03501Galactose-uridine-5'-diphosphateBeta-1,4-galactosyltransferase 1target
DB03800Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB03800Deoxyuridine monophosphateThymidylate synthase ThyXtarget
DB03800Deoxyuridine monophosphatePol polyproteintarget
DB03800Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB04672Cyclic 3',5'-thymidine monophosphate5'(3')-deoxyribonucleotidase, mitochondrialtarget
DB04983DenufosolP2Y purinoceptor 2target
DB08934SofosbuvirP-glycoprotein 1transporter
DB08934SofosbuvirATP-binding cassette sub-family G member 2transporter
DB08934SofosbuvirRNA-dependent RNA-polymerasetarget
DB08934SofosbuvirLysosomal protective proteinenzyme
DB08934SofosbuvirCarboxylesteraseenzyme
DB08934SofosbuvirHistidine triad nucleotide-binding protein 1enzyme
DB08934SofosbuvirUMP-CMP kinaseenzyme
DB08934SofosbuvirNucleoside diphosphate kinase Aenzyme
DB01861Uridine diphosphate glucoseGalactose-1-phosphate uridylyltransferasetarget
DB01861Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
DB01861Uridine diphosphate glucoseAlpha,alpha-trehalose-phosphate synthase [UDP-forming]target
DB01861Uridine diphosphate glucoseGlucose-1-phosphate thymidylyltransferasetarget
DB01861Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
DB01861Uridine diphosphate glucoseDNA beta-glucosyltransferasetarget
DB01861Uridine diphosphate glucoseGlycosyltransferase 6 domain-containing protein 1target
DB01861Uridine diphosphate glucoseWbpPtarget
DB01861Uridine diphosphate glucoseGlycogenin-1target
DB027143'-UridinemonophosphateRibonuclease pancreatictarget
DB032582'-Deoxycytidine 5'-triphosphateAnaerobic ribonucleoside-triphosphate reductasetarget
DB032582'-Deoxycytidine 5'-triphosphateDeoxycytidine triphosphate deaminasetarget
DB032582'-Deoxycytidine 5'-triphosphateDNA polymerase I, thermostabletarget
DB032582'-Deoxycytidine 5'-triphosphateRibonucleoside-diphosphate reductase 2 subunit alphatarget
DB03403Cytidine-5'-MonophosphateUridine-cytidine kinase 2target
DB03403Cytidine-5'-Monophosphate3-deoxy-manno-octulosonate cytidylyltransferasetarget
DB03403Cytidine-5'-Monophosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
DB03403Cytidine-5'-MonophosphateBifunctional enzyme IspD/IspFtarget
DB03403Cytidine-5'-MonophosphateUMP-CMP kinasetarget
DB03403Cytidine-5'-Monophosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
DB03403Cytidine-5'-MonophosphateCytidylate kinasetarget
DB03403Cytidine-5'-MonophosphateCoenzyme A biosynthesis bifunctional protein CoaBCtarget
DB03403Cytidine-5'-MonophosphateAlpha-2,3-/2,8-sialyltransferasetarget
DB03685Uridine monophosphateUridine-cytidine kinase-like 1target
DB03685Uridine monophosphateGalactose-1-phosphate uridylyltransferasetarget
DB03685Uridine monophosphateThymidylate synthasetarget
DB03685Uridine monophosphateGlycosyltransferase 6 domain-containing protein 1target
DB03685Uridine monophosphateU6 snRNA-associated Sm-like protein LSm6target
DB03685Uridine monophosphateUracil phosphoribosyltransferasetarget
DB03685Uridine monophosphateBeta-1,4-galactosyltransferase 1target
DB03685Uridine monophosphateInterferon-stimulated gene 20 kDa proteintarget
DB03685Uridine monophosphateOrotidine 5'-phosphate decarboxylasetarget
DB03685Uridine monophosphateBifunctional protein PyrRtarget
DB03685Uridine monophosphateUracil phosphoribosyltransferasetarget
DB03685Uridine monophosphateBifunctional polymyxin resistance protein ArnAtarget
DB03685Uridine monophosphateRibosomal small subunit pseudouridine synthase Atarget
DB04005Uridine 5'-triphosphateUridine-cytidine kinase 2target
DB04005Uridine 5'-triphosphateGenome polyproteintarget
DB04005Uridine 5'-triphosphateGenome polyproteintarget
DB12153CiticolineLicC proteintarget
DB03666Zidovudine monophosphateThymidylate kinasetarget
DB03666Zidovudine monophosphateThymidylate kinasetarget
DB04542Zidovudine diphosphateNucleoside diphosphate kinase Atarget
DB04243TMPSingle-stranded DNA-binding proteintarget