Nicotinic Antagonists

Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
DrugDrug NameDrug Description
DB00483Gallamine triethiodideA nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation.
DB00657MecamylamineA nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension.
DB00732Atracurium besylateA non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery.
DB01090PentoliniumUsed to produce controlled hypotension during surgical procedures and in hypertensive crises.
DB01116TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
DB01199TubocurarineA neuromuscular blocker used for the diagnosis of and facilitation of intubation after induction of anesthesia during surgical procedures.
DB01337PancuroniumA neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
DB01338PipecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles during anesthesia and surgical procedures.
DB01339VecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures.
DB13295AtracuriumNot Annotated
DB13584GallamineNot Annotated
DB13648AlcuroniumA non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
DB00333MethadoneAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
DB01161ChloroprocaineA local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, or spinal anesthesia.
DB00416Metocurine iodideFor use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
DB00728RocuroniumA vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.
DB00810BiperidenA muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs.
DB01135DoxacuriumA nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures.
DB01226MivacuriumA short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation.
DB00514DextromethorphanAn NMDA receptor antagonist used to treat cases of dry cough.
DB01336MetocurineMetocurine is a muscle relaxant.
DB00721ProcaineA local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.
DB01351AmobarbitalA barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures.
DB00312PentobarbitalA barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures.
DB00237ButabarbitalA barbiturate drug used as a sedative and hypnotic.
DB00241ButalbitalA barbiturate drug used for symptomatic treatment of tension-type headache in various combinations with acetaminophen, aspirin, caffeine, and codeine.
DB00306TalbutalFor use as a sedative and hypnotic.
DB00418SecobarbitalA barbiturate used for the short-term treatment of insomnia.
DB00463MetharbitalMetharbital is used for the treatment of epilepsy.
DB00599ThiopentalA barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
DB00794PrimidoneAn antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
DB00849MethylphenobarbitalFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
DB01174PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
DB01352AprobarbitalAprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment...
DB01353ButobarbitalFor the treatment of insomnia.
DB01354HeptabarbitalUsed mainly for sedation and hypnosis.
DB01355HexobarbitalFor the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful...
DB01483BarbitalA long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice...
DB01496Barbituric acid derivativeNot Available
DB01227LevacetylmethadolFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
DB08838AgmatineAgmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,...
DB00565CisatracuriumA skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation.
DB05710GantacuriumInvestigated for use/treatment in anesthesia (unspecified).
DB08960HexamethoniumA nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been...
DB00753IsofluraneAn inhaled general anesthetic used in surgery.
DB00915AmantadineA medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
DB00472FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
DB00941HexafluroniumUsed as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations.
DrugDrug NameTargetType
DB00483Gallamine triethiodideNeuronal acetylcholine receptor subunit alpha-2target
DB00483Gallamine triethiodideMuscarinic acetylcholine receptor M2target
DB00483Gallamine triethiodideAcetylcholinesterasetarget
DB00483Gallamine triethiodideMuscarinic acetylcholine receptor M1target
DB00483Gallamine triethiodideMuscarinic acetylcholine receptor M5target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-2target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-7target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-4target
DB00657MecamylamineNeuronal acetylcholine receptor subunit beta-2target
DB00732Atracurium besylateNeuronal acetylcholine receptor subunit alpha-2target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-10target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-3target
DB01090PentoliniumNeuronal acetylcholine receptor subunit beta-4target
DB01116TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
DB01116TrimethaphanCholinesteraseenzyme
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
DB01199TubocurarineAcetylcholinesterasetarget
DB01199Tubocurarine5-hydroxytryptamine receptor 3Atarget
DB01199TubocurarineSolute carrier family 22 member 1transporter
DB01199TubocurarineSolute carrier family 22 member 2transporter
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
DB01199TubocurarineCholinesteraseenzyme
DB01337PancuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB01337PancuroniumCholinesteraseenzyme
DB01337PancuroniumMuscarinic acetylcholine receptor M2target
DB01337PancuroniumMuscarinic acetylcholine receptor M3target
DB01337PancuroniumSolute carrier family 22 member 1transporter
DB01337PancuroniumSolute carrier family 22 member 2transporter
DB01338PipecuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB01338PipecuroniumMuscarinic acetylcholine receptor M2target
DB01338PipecuroniumMuscarinic acetylcholine receptor M3target
DB01338PipecuroniumCholinesteraseenzyme
DB01339VecuroniumP-glycoprotein 1transporter
DB01339VecuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB00333MethadoneNMDA receptortarget
DB00333MethadoneMu-type opioid receptortarget
DB00333MethadoneCytochrome P450 2B6enzyme
DB00333MethadoneCytochrome P450 3A4enzyme
DB00333MethadoneCytochrome P450 2C19enzyme
DB00333MethadoneDelta-type opioid receptortarget
DB00333MethadoneCytochrome P450 3A7enzyme
DB00333MethadoneCytochrome P450 2D6enzyme
DB00333MethadoneP-glycoprotein 1transporter
DB00333MethadoneCytochrome P450 2C8enzyme
DB00333MethadoneCytochrome P450 19A1enzyme
DB00333MethadoneCytochrome P450 1A2enzyme
DB00333MethadoneCytochrome P450 2C18enzyme
DB00333MethadoneCytochrome P450 2C9enzyme
DB00333Methadone5-hydroxytryptamine receptor 3Atarget
DB00333MethadoneAlpha-1-acid glycoprotein 1carrier
DB00333MethadoneSerum albumincarrier
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-7target
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-3target
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-4target
DB00333MethadoneNeuronal acetylcholine receptor subunit beta-2target
DB01161ChloroprocaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineNeuronal acetylcholine receptor subunit alpha-10target
DB01161ChloroprocaineSodium-dependent dopamine transportertarget
DB01161ChloroprocaineGlutamate receptor ionotropic, NMDA 3Atarget
DB01161Chloroprocaine5-hydroxytryptamine receptor 3Atarget
DB01161ChloroprocaineCholinesteraseenzyme
DB00416Metocurine iodideNeuronal acetylcholine receptor subunit alpha-2target
DB00728RocuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB00728RocuroniumMuscarinic acetylcholine receptor M2target
DB00728Rocuronium5-hydroxytryptamine receptor 3Atarget
DB00728RocuroniumSolute carrier family 22 member 1transporter
DB00728RocuroniumSolute carrier organic anion transporter family member 1A2transporter
DB00810BiperidenNeuronal acetylcholine receptor subunit alpha-2target
DB00810BiperidenMuscarinic acetylcholine receptor M1target
DB00810BiperidenCytochrome P450 2D6enzyme
DB01135DoxacuriumNeuronal acetylcholine receptor subunit alpha-2target
DB01135DoxacuriumMuscarinic acetylcholine receptor M2target
DB01135DoxacuriumCholinesteraseenzyme
DB01226MivacuriumNeuronal acetylcholine receptor subunit alpha-2target
DB01226MivacuriumMuscarinic acetylcholine receptor M2target
DB01226MivacuriumMuscarinic acetylcholine receptor M3target
DB01226MivacuriumCholinesterasetarget
DB00514DextromethorphanSigma non-opioid intracellular receptor 1target
DB00514DextromethorphanHCG20471, isoform CRA_ctarget
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DB00514DextromethorphanSodium-dependent serotonin transportertarget
DB00514DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DB00514DextromethorphanCytochrome P450 2D6enzyme
DB00514DextromethorphanCytochrome P450 3A4enzyme
DB00514DextromethorphanCytochrome P450 3A7enzyme
DB00514DextromethorphanCytochrome P450 2C9enzyme
DB00514DextromethorphanCytochrome P450 2B6enzyme
DB00514DextromethorphanCytochrome P450 2C19enzyme
DB00514DextromethorphanMembrane-associated progesterone receptor component 1target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DB00514DextromethorphanMu-type opioid receptortarget
DB00514DextromethorphanDelta-type opioid receptortarget
DB00514DextromethorphanKappa-type opioid receptortarget
DB00514DextromethorphanNADPH oxidasetarget
DB00514DextromethorphanSodium-dependent noradrenaline transportertarget
DB01336MetocurineNeuronal acetylcholine receptor subunit alpha-2target
DB01336MetocurineMuscarinic acetylcholine receptor M2target
DB00721ProcaineSodium channel protein type 10 subunit alphatarget
DB00721ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
DB00721Procaine5-hydroxytryptamine receptor 3Atarget
DB00721ProcaineSodium-dependent dopamine transportertarget
DB00721ProcaineNeuronal acetylcholine receptor subunit alpha-2target
DB00721ProcaineCholinesteraseenzyme
DB00721ProcaineDNAtarget
DB00721ProcaineCalcium-activated potassium channeltarget
DB00721ProcaineCytosolic phospholipase A2target
DB00721Procaine60 kDa lysophospholipasetarget
DB00721ProcaineMonoamine oxidasetarget
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01351AmobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01351AmobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01351AmobarbitalGlutamate receptor 2target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01351AmobarbitalGlutamate receptor ionotropic, kainate 2target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00312PentobarbitalCytochrome P450 3A4enzyme
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00312PentobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00312PentobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00312PentobarbitalGlutamate receptor 2target
DB00312PentobarbitalGlutamate receptor ionotropic, kainate 2target
DB00312PentobarbitalCytochrome P450 2C19enzyme
DB00312PentobarbitalCytochrome P450 2A6enzyme
DB00312PentobarbitalGABA-A receptor (anion channel)target
DB00312PentobarbitalNMDA receptortarget
DB00312PentobarbitalNuclear receptor subfamily 1 group I member 2target
DB00237ButabarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00237ButabarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00237ButabarbitalGlutamate receptor 2target
DB00237ButabarbitalGlutamate receptor ionotropic, kainate 2target
DB00237ButabarbitalGABA-A receptor (anion channel)target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00241ButalbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00241ButalbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00241ButalbitalGlutamate receptor 2target
DB00241ButalbitalGlutamate receptor ionotropic, kainate 2target
DB00241ButalbitalGABA-A receptor (anion channel)target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-1target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-2target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-3target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-4target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-5target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-6target
DB00306TalbutalNeuronal acetylcholine receptor subunit alpha-4target
DB00306TalbutalNeuronal acetylcholine receptor subunit alpha-7target
DB00306TalbutalGlutamate receptor 2target
DB00306TalbutalGlutamate receptor ionotropic, kainate 2target
DB00306TalbutalGABA-A receptor (anion channel)target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00418SecobarbitalCytochrome P450 2C8enzyme
DB00418SecobarbitalCytochrome P450 2C9enzyme
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00418SecobarbitalGlutamate receptor 2target
DB00418SecobarbitalGlutamate receptor ionotropic, kainate 2target
DB00418SecobarbitalCytochrome P450 1A2enzyme
DB00418SecobarbitalNMDA receptortarget
DB00418SecobarbitalCytochrome P450 2C19enzyme
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00463MetharbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00463MetharbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00463MetharbitalGlutamate receptor 2target
DB00463MetharbitalGlutamate receptor ionotropic, kainate 2target
DB00463MetharbitalGABA-A receptor (anion channel)target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-1target
DB00599ThiopentalFatty-acid amide hydrolase 1target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-2target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-3target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-4target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-5target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-6target
DB00599ThiopentalNeuronal acetylcholine receptor subunit alpha-4target
DB00599ThiopentalNeuronal acetylcholine receptor subunit alpha-7target
DB00599ThiopentalGlutamate receptor 2target
DB00599ThiopentalGlutamate receptor ionotropic, kainate 2target
DB00599ThiopentalCytochrome P450 3A Subfamilyenzyme
DB00599ThiopentalMuscarinic acetylcholine receptor M3target
DB00599ThiopentalCytochrome P450 2C19enzyme
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
DB00794PrimidoneCytochrome P450 2C19enzyme
DB00794PrimidoneCytochrome P450 1A2enzyme
DB00794PrimidoneCytochrome P450 2C9enzyme
DB00794PrimidoneCytochrome P450 3A4enzyme
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
DB00794PrimidoneGlutamate receptor 2target
DB00794PrimidoneGlutamate receptor ionotropic, kainate 2target
DB00794PrimidoneGABA-A receptor (anion channel)target
DB00794PrimidoneUDP-glucuronosyltransferase 1-1enzyme
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00849MethylphenobarbitalCytochrome P450 2C19enzyme
DB00849MethylphenobarbitalCytochrome P450 2B6enzyme
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00849MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00849MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00849MethylphenobarbitalGlutamate receptor 2target
DB00849MethylphenobarbitalGlutamate receptor ionotropic, kainate 2target
DB00849MethylphenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01174PhenobarbitalCytochrome P450 2C19enzyme
DB01174PhenobarbitalCytochrome P450 2C9enzyme
DB01174PhenobarbitalCytochrome P450 2B6enzyme
DB01174PhenobarbitalCytochrome P450 2C8enzyme
DB01174PhenobarbitalCytochrome P450 1A2enzyme
DB01174PhenobarbitalCytochrome P450 3A4enzyme
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
DB01174PhenobarbitalBile salt export pumptransporter
DB01174PhenobarbitalP-glycoprotein 1transporter
DB01174PhenobarbitalMultidrug resistance-associated protein 1transporter
DB01174PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01174PhenobarbitalGlutamate receptor 2target
DB01174PhenobarbitalGlutamate receptor ionotropic, kainate 2target
DB01174PhenobarbitalCytochrome P450 2A6enzyme
DB01174PhenobarbitalCytochrome P450 2E1enzyme
DB01174PhenobarbitalCytochrome P450 3A5enzyme
DB01174PhenobarbitalCytochrome P450 1A1enzyme
DB01174PhenobarbitalCytochrome P450 2C18enzyme
DB01174PhenobarbitalCytochrome P450 3A7enzyme
DB01174PhenobarbitalCytochrome P450 4B1enzyme
DB01174PhenobarbitalNMDA receptortarget
DB01174PhenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
DB01174PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01352AprobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01352AprobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01352AprobarbitalGlutamate receptor 2target
DB01352AprobarbitalGlutamate receptor ionotropic, kainate 2target
DB01352AprobarbitalCytochrome P450 3A4enzyme
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01353ButobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01353ButobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01353ButobarbitalGlutamate receptor 2target
DB01353ButobarbitalGlutamate receptor ionotropic, kainate 2target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01354HeptabarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01354HeptabarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01354HeptabarbitalGlutamate receptor 2target
DB01354HeptabarbitalGlutamate receptor ionotropic, kainate 2target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01355HexobarbitalCytochrome P450 2C9enzyme
DB01355HexobarbitalCytochrome P450 2C19enzyme
DB01355HexobarbitalProstaglandin G/H synthase 1enzyme
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01355HexobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01355HexobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01355HexobarbitalGlutamate receptor 2target
DB01355HexobarbitalGlutamate receptor ionotropic, kainate 2target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01483BarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01483BarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01483BarbitalGlutamate receptor 2target
DB01483BarbitalGlutamate receptor ionotropic, kainate 2target
DB01483BarbitalCytochrome P450 3A4enzyme
DB01483BarbitalCytochrome P450 2C19enzyme
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-1target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-2target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-3target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-4target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-5target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-6target
DB01496Barbituric acid derivativeNeuronal acetylcholine receptor subunit alpha-4target
DB01496Barbituric acid derivativeNeuronal acetylcholine receptor subunit alpha-7target
DB01496Barbituric acid derivativeGlutamate receptor 2target
DB01496Barbituric acid derivativeGlutamate receptor ionotropic, kainate 2target
DB01227LevacetylmethadolMu-type opioid receptortarget
DB01227LevacetylmethadolCytochrome P450 3A4enzyme
DB01227LevacetylmethadolNeuronal acetylcholine receptor subunit beta-4target
DB01227LevacetylmethadolNeuronal acetylcholine receptor subunit alpha-3target
DB01227LevacetylmethadolCytochrome P450 3A5enzyme
DB01227LevacetylmethadolCytochrome P450 3A7enzyme
DB08838AgmatineSolute carrier family 22 member 1transporter
DB08838AgmatineSolute carrier family 22 member 2transporter
DB08838AgmatineSolute carrier family 22 member 3transporter
DB08838AgmatineAlpha-2C adrenergic receptortarget
DB08838AgmatineNischarintarget
DB08838AgmatineAcetylcholine receptor subunit alphatarget
DB08838AgmatineGlutamate receptor ionotropic, NMDA 1target
DB08838AgmatineATP-sensitive inward rectifier potassium channel 1target
DB08838AgmatineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB08838AgmatineAcid-sensing ion channel 3target
DB08838AgmatineY+L amino acid transporter 1transporter
DB08838AgmatineCytochrome P450 3A4enzyme
DB00565CisatracuriumNeuronal acetylcholine receptor subunit alpha-2target
DB05710GantacuriumNeuronal acetylcholine receptor subunit alpha-3target
DB08960HexamethoniumNeuronal acetylcholine receptor subunit alpha-2target
DB00753IsofluraneCalcium-transporting ATPase type 2C member 1target
DB00753IsofluraneATP synthase subunit delta, mitochondrialtarget
DB00753IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB00753IsofluranePotassium voltage-gated channel subfamily A member 1target
DB00753IsofluraneGlutamate receptor 1target
DB00753IsofluraneGlycine receptor subunit alpha-1target
DB00753IsofluraneCalmodulintarget
DB00753IsofluraneCytochrome P450 2E1enzyme
DB00753IsofluraneSerum albumincarrier
DB00753IsofluraneCytochrome P450 2B6enzyme
DB00753IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
DB00753IsofluraneGABA-A receptor (anion channel)target
DB00753IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
DB00753IsofluraneNeuronal acetylcholine receptor subunit beta-2target
DB00915AmantadineDopamine D2 receptortarget
DB00915AmantadineMatrix protein 2target
DB00915AmantadineAromatic-L-amino-acid decarboxylaseenzyme
DB00915AmantadineAmine oxidase [flavin-containing] Benzyme
DB00915AmantadineSolute carrier family 22 member 2transporter
DB00915AmantadineSolute carrier family 22 member 1transporter
DB00915AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-7target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-4target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineP-glycoprotein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target
DB00941HexafluroniumCholinesterasetarget