Nicotinic Antagonists

Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
DrugDrug NameDrug Indication
DB00483Gallamine TriethiodideFor use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilation
DB00657MecamylamineFor the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
DB00732Atracurium besylateFor use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
DB01090PentoliniumUsed to produce controlled hypotension during surgical procedures and in hypertensive crises.
DB01116TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
DB01199TubocurarineUsed as a diagnosis agent for myasthenia gravis, and also to facilitate the intubation after induction of anesthesia in surgical procedure
DB01337PancuroniumUsed as a muscle relaxant during anesthesia and surgical procedures.
DB01338PipecuroniumUsed as a muscle relaxant during anesthesia and surgical procedures.
DB01339VecuroniumVecuronium is a muscle relaxing agent and is used as an ajunct in general anesthesia.
DB13295AtracuriumNot Available
DB13584GallamineNot Available
DB13648AlcuroniumNot Available
DB00333MethadoneFor the treatment of dry cough, drug withdrawal syndrome, opioid type drug dependence, and pain.
DB01161ChloroprocaineFor the production of local anesthesia by infiltration and peripheral nerve block. They are not to be used for lumbar or caudal epidural anesthesia.
DB00416Metocurine IodideFor use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
DB00728RocuroniumFor inpatients and outpatients as an adjunct to general anesthesia to facilitate both rapid sequence and routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
DB00810BiperidenFor use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.
DB01135DoxacuriumUsed to provide skeletal muscle relaxation as an adjunct to general anesthesia, for endotracheal intubation or to facilitate mechanical ventilation.
DB01226MivacuriumFor inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
DB00514DextromethorphanFor treatment and relief of dry cough.
DB01336MetocurineMetocurine is a muscle relaxant.
DB00721ProcaineUsed as a local anesthetic primarily in oral surgery
DB01351AmobarbitalNot Available
DB00312PentobarbitalFor the short-term treatment of insomnia.
DB00237ButabarbitalFor short-term treatment of insomnia and anxiety disorders
DB00241ButalbitalIndicated for the management of the symptom complex of tension (or muscle contraction) headache, when other non-opioid analgesics and alternative treatments are inadequate, in various combinations with acetaminophen, aspirin, caffeine, and codeine [FDA Label].
DB00306TalbutalFor use as a sedative and hypnotic.
DB00418SecobarbitalFor the Short-term treatment of intractable insomnia for patients habituated to barbiturates
DB00463MetharbitalMetharbital is used for the treatment of epilepsy.
DB00599ThiopentalFor use as the sole anesthetic agent for brief (15 minute) procedures, for induction of anesthesia prior to administration of other anesthetic agents, to supplement regional anesthesia, to provide hypnosis during balanced anesthesia with other agents for analgesia or muscle relaxation, for the control of convulsive states during or following inhalation anesthesia or local anesthesia, in neurosurgical patients with increased intracranial pressure, and for narcoanalysis and narcosynthesis in psychiatric disorders.
DB00794PrimidonePrimidone is commonly indicated for the management of grand mal, psychomotor, and focal epileptic seizures [L4645, FDA Label]. In addition, it has also been studied and utilized as an effective management of essential tremor [A39414, A39415, L4645].
DB00849MethylphenobarbitalFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
DB01174PhenobarbitalFor the treatment of all types of seizures except absence seizures.
DB01352AprobarbitalNot Available
DB01353ButobarbitalFor the treatment of insomnia.
DB01354HeptabarbitalUsed mainly for sedation and hypnosis.
DB01355HexobarbitalFor the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli.
DB01483BarbitalNot Available
DB01496Barbituric acid derivativeNot Available
DB01227LevacetylmethadolFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
DB01156BupropionBupropion is indicated for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. Bupropion is also used off-label as a first-line treatment in patients with ADHD and comorbid bipolar disorder when used as an adjunct to mood stabilizers.[F4624]
DB08838AgmatineAgmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety, schizophrenia, and cognition). As an investigational drug, agamatine is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy.
DB00565CisatracuriumFor inpatients and outpatients as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation in the ICU.
DB05710GantacuriumInvestigated for use/treatment in anesthesia (unspecified).
DB08960HexamethoniumNot Available
DB00753IsofluraneFor induction and maintenance of general anesthesia.
DB00915AmantadineFor the chemoprophylaxis, prophylaxis, and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Also for the treatment of parkinsonism and drug-induced extrapyramidal reactions.
DB00472FluoxetineLabeled indication include: major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism, mild dementia-associated agitation in nonpsychotic patients, post-traumatic stress disorder (PTSD), social anxiety disorder, chronic neuropathic pain, fibromyalgia, and Raynaud's phenomenon.
DrugDrug NameTargetType
DB00483Gallamine TriethiodideNeuronal acetylcholine receptor subunit alpha-2target
DB00483Gallamine TriethiodideMuscarinic acetylcholine receptor M2target
DB00483Gallamine TriethiodideAcetylcholinesterasetarget
DB00483Gallamine TriethiodideMuscarinic acetylcholine receptor M1target
DB00483Gallamine TriethiodideMuscarinic acetylcholine receptor M5target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-2target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-7target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-4target
DB00657MecamylamineNeuronal acetylcholine receptor subunit beta-2target
DB00732Atracurium besylateNeuronal acetylcholine receptor subunit alpha-2target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-10target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-3target
DB01090PentoliniumNeuronal acetylcholine receptor subunit beta-4target
DB01116TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
DB01116TrimethaphanCholinesteraseenzyme
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
DB01199TubocurarineAcetylcholinesterasetarget
DB01199Tubocurarine5-hydroxytryptamine receptor 3Atarget
DB01199TubocurarineSolute carrier family 22 member 1transporter
DB01199TubocurarineSolute carrier family 22 member 2transporter
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
DB01199TubocurarineCholinesteraseenzyme
DB01337PancuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB01337PancuroniumCholinesteraseenzyme
DB01337PancuroniumMuscarinic acetylcholine receptor M2target
DB01337PancuroniumMuscarinic acetylcholine receptor M3target
DB01337PancuroniumSolute carrier family 22 member 1transporter
DB01337PancuroniumSolute carrier family 22 member 2transporter
DB01338PipecuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB01338PipecuroniumMuscarinic acetylcholine receptor M2target
DB01338PipecuroniumMuscarinic acetylcholine receptor M3target
DB01338PipecuroniumCholinesteraseenzyme
DB01339VecuroniumMultidrug resistance protein 1transporter
DB01339VecuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB00333MethadoneGlutamate receptor ionotropic, NMDA 3Atarget
DB00333MethadoneMu-type opioid receptortarget
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-10target
DB00333MethadoneCytochrome P450 2B6enzyme
DB00333MethadoneCytochrome P450 3A4enzyme
DB00333MethadoneCytochrome P450 2C19enzyme
DB00333MethadoneDelta-type opioid receptortarget
DB00333MethadoneCytochrome P450 3A5enzyme
DB00333MethadoneCytochrome P450 3A7enzyme
DB00333MethadoneCytochrome P450 2D6enzyme
DB00333MethadoneMultidrug resistance protein 1transporter
DB00333MethadoneCytochrome P450 2C8enzyme
DB00333MethadoneCytochrome P450 19A1enzyme
DB00333MethadoneCytochrome P450 1A2enzyme
DB00333MethadoneCytochrome P450 2C18enzyme
DB00333MethadoneCytochrome P450 2C9enzyme
DB00333Methadone5-hydroxytryptamine receptor 3Atarget
DB00333MethadoneLymphocyte antigen 96target
DB00333MethadoneAlpha-1-acid glycoprotein 2target
DB00333MethadoneThyroxine-binding globulincarrier
DB01161ChloroprocaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineNeuronal acetylcholine receptor subunit alpha-10target
DB01161ChloroprocaineSodium-dependent dopamine transportertarget
DB01161ChloroprocaineGlutamate receptor ionotropic, NMDA 3Atarget
DB01161Chloroprocaine5-hydroxytryptamine receptor 3Atarget
DB01161ChloroprocaineCholinesteraseenzyme
DB00416Metocurine IodideNeuronal acetylcholine receptor subunit alpha-2target
DB00728RocuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB00728RocuroniumMuscarinic acetylcholine receptor M2target
DB00728Rocuronium5-hydroxytryptamine receptor 3Atarget
DB00728RocuroniumSolute carrier family 22 member 1transporter
DB00728RocuroniumSolute carrier organic anion transporter family member 1A2transporter
DB00810BiperidenNeuronal acetylcholine receptor subunit alpha-2target
DB00810BiperidenMuscarinic acetylcholine receptor M1target
DB00810BiperidenCytochrome P450 2D6enzyme
DB01135DoxacuriumNeuronal acetylcholine receptor subunit alpha-2target
DB01135DoxacuriumMuscarinic acetylcholine receptor M2target
DB01135DoxacuriumCholinesteraseenzyme
DB01226MivacuriumNeuronal acetylcholine receptor subunit alpha-2target
DB01226MivacuriumMuscarinic acetylcholine receptor M2target
DB01226MivacuriumMuscarinic acetylcholine receptor M3target
DB01226MivacuriumCholinesterasetarget
DB00514DextromethorphanSigma non-opioid intracellular receptor 1target
DB00514DextromethorphanHCG20471, isoform CRA_ctarget
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DB00514DextromethorphanSodium-dependent serotonin transportertarget
DB00514DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DB00514DextromethorphanCytochrome P450 2D6enzyme
DB00514DextromethorphanCytochrome P450 3A4enzyme
DB00514DextromethorphanCytochrome P450 3A5enzyme
DB00514DextromethorphanCytochrome P450 3A7enzyme
DB00514DextromethorphanCytochrome P450 2C9enzyme
DB00514DextromethorphanCytochrome P450 2B6enzyme
DB00514DextromethorphanCytochrome P450 2C19enzyme
DB00514DextromethorphanCytochrome P450 2C8enzyme
DB00514DextromethorphanCytochrome P450 2E1enzyme
DB00514DextromethorphanMembrane-associated progesterone receptor component 1target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DB00514DextromethorphanMu-type opioid receptortarget
DB00514DextromethorphanDelta-type opioid receptortarget
DB00514DextromethorphanKappa-type opioid receptortarget
DB00514DextromethorphanNADPH oxidasetarget
DB00514DextromethorphanSodium-dependent noradrenaline transportertarget
DB01336MetocurineNeuronal acetylcholine receptor subunit alpha-2target
DB01336MetocurineMuscarinic acetylcholine receptor M2target
DB00721ProcaineSodium channel protein type 10 subunit alphatarget
DB00721ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
DB00721Procaine5-hydroxytryptamine receptor 3Atarget
DB00721ProcaineSodium-dependent dopamine transportertarget
DB00721ProcaineNeuronal acetylcholine receptor subunit alpha-2target
DB00721ProcaineCholinesteraseenzyme
DB00721ProcaineDNAtarget
DB00721ProcaineCalcium-activated potassium channeltarget
DB00721ProcainePhospholipase A2target
DB00721ProcaineLysophospholipasetarget
DB00721ProcaineMonoamine oxidasetarget
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01351AmobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01351AmobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01351AmobarbitalGlutamate receptor 2target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01351AmobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01351AmobarbitalGlutamate receptor ionotropic, kainate 2target
DB01351AmobarbitalCytochrome P450 2A6enzyme
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00312PentobarbitalCytochrome P450 3A4enzyme
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00312PentobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00312PentobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00312PentobarbitalGlutamate receptor 2target
DB00312PentobarbitalGlutamate receptor ionotropic, kainate 2target
DB00312PentobarbitalCytochrome P450 2C19enzyme
DB00312PentobarbitalCytochrome P450 2A6enzyme
DB00312PentobarbitalGABA-A receptor (anion channel)target
DB00312PentobarbitalNMDA receptortarget
DB00312PentobarbitalNuclear receptor subfamily 1 group I member 2target
DB00237ButabarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00237ButabarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00237ButabarbitalGlutamate receptor 2target
DB00237ButabarbitalGlutamate receptor ionotropic, kainate 2target
DB00237ButabarbitalGABA-A receptor (anion channel)target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00241ButalbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00241ButalbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00241ButalbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00241ButalbitalGlutamate receptor 2target
DB00241ButalbitalGlutamate receptor ionotropic, kainate 2target
DB00241ButalbitalGABA-A receptor (anion channel)target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-1target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-2target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-3target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-4target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-5target
DB00306TalbutalGamma-aminobutyric acid receptor subunit alpha-6target
DB00306TalbutalNeuronal acetylcholine receptor subunit alpha-4target
DB00306TalbutalNeuronal acetylcholine receptor subunit alpha-7target
DB00306TalbutalGlutamate receptor 2target
DB00306TalbutalGlutamate receptor ionotropic, kainate 2target
DB00306TalbutalGABA-A receptor (anion channel)target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00418SecobarbitalCytochrome P450 2C8enzyme
DB00418SecobarbitalCytochrome P450 2C9enzyme
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00418SecobarbitalGlutamate receptor 2target
DB00418SecobarbitalGlutamate receptor ionotropic, kainate 2target
DB00418SecobarbitalCytochrome P450 1A2enzyme
DB00418SecobarbitalNMDA receptortarget
DB00418SecobarbitalCytochrome P450 2C19enzyme
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00463MetharbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00463MetharbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00463MetharbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00463MetharbitalGlutamate receptor 2target
DB00463MetharbitalGlutamate receptor ionotropic, kainate 2target
DB00463MetharbitalGABA-A receptor (anion channel)target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-1target
DB00599ThiopentalFatty-acid amide hydrolase 1target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-2target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-3target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-4target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-5target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-6target
DB00599ThiopentalNeuronal acetylcholine receptor subunit alpha-4target
DB00599ThiopentalNeuronal acetylcholine receptor subunit alpha-7target
DB00599ThiopentalGlutamate receptor 2target
DB00599ThiopentalGlutamate receptor ionotropic, kainate 2target
DB00599ThiopentalCytochrome P450 2E1enzyme
DB00599ThiopentalCytochrome P450 3A4enzyme
DB00599ThiopentalMuscarinic acetylcholine receptor M3target
DB00599ThiopentalCytochrome P450 2C19enzyme
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
DB00794PrimidoneCytochrome P450 2C19enzyme
DB00794PrimidoneCytochrome P450 1A2enzyme
DB00794PrimidoneCytochrome P450 2B6enzyme
DB00794PrimidoneCytochrome P450 2C8enzyme
DB00794PrimidoneCytochrome P450 2C9enzyme
DB00794PrimidoneCytochrome P450 3A4enzyme
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
DB00794PrimidoneGlutamate receptor 2target
DB00794PrimidoneGlutamate receptor ionotropic, kainate 2target
DB00794PrimidoneGABA-A receptor (anion channel)target
DB00794PrimidoneUDP-glucuronosyltransferase 1-1enzyme
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00849MethylphenobarbitalCytochrome P450 2C19enzyme
DB00849MethylphenobarbitalCytochrome P450 2B6enzyme
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00849MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00849MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00849MethylphenobarbitalGlutamate receptor 2target
DB00849MethylphenobarbitalGlutamate receptor ionotropic, kainate 2target
DB00849MethylphenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01174PhenobarbitalCytochrome P450 2C19enzyme
DB01174PhenobarbitalCytochrome P450 2C9enzyme
DB01174PhenobarbitalCytochrome P450 2B6enzyme
DB01174PhenobarbitalCytochrome P450 2C8enzyme
DB01174PhenobarbitalCytochrome P450 1A2enzyme
DB01174PhenobarbitalCytochrome P450 3A4enzyme
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
DB01174PhenobarbitalBile salt export pumptransporter
DB01174PhenobarbitalMultidrug resistance protein 1transporter
DB01174PhenobarbitalMultidrug resistance-associated protein 1transporter
DB01174PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01174PhenobarbitalGlutamate receptor 2target
DB01174PhenobarbitalGlutamate receptor ionotropic, kainate 2target
DB01174PhenobarbitalCytochrome P450 2A6enzyme
DB01174PhenobarbitalCytochrome P450 2E1enzyme
DB01174PhenobarbitalCytochrome P450 3A5enzyme
DB01174PhenobarbitalCytochrome P450 4A11enzyme
DB01174PhenobarbitalCytochrome P450 1A1enzyme
DB01174PhenobarbitalCytochrome P450 1B1enzyme
DB01174PhenobarbitalCytochrome P450 2C18enzyme
DB01174PhenobarbitalCytochrome P450 3A7enzyme
DB01174PhenobarbitalCytochrome P450 4B1enzyme
DB01174PhenobarbitalNMDA receptortarget
DB01174PhenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
DB01174PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01352AprobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01352AprobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01352AprobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01352AprobarbitalGlutamate receptor 2target
DB01352AprobarbitalGlutamate receptor ionotropic, kainate 2target
DB01352AprobarbitalCytochrome P450 3A4enzyme
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01353ButobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01353ButobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01353ButobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01353ButobarbitalGlutamate receptor 2target
DB01353ButobarbitalGlutamate receptor ionotropic, kainate 2target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01354HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01354HeptabarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01354HeptabarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01354HeptabarbitalGlutamate receptor 2target
DB01354HeptabarbitalGlutamate receptor ionotropic, kainate 2target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01355HexobarbitalCytochrome P450 2E1enzyme
DB01355HexobarbitalCytochrome P450 2C9enzyme
DB01355HexobarbitalCytochrome P450 2C19enzyme
DB01355HexobarbitalProstaglandin G/H synthase 1enzyme
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01355HexobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01355HexobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01355HexobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01355HexobarbitalGlutamate receptor 2target
DB01355HexobarbitalGlutamate receptor ionotropic, kainate 2target
DB01355HexobarbitalCytochrome P450 3A4enzyme
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB01483BarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB01483BarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01483BarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01483BarbitalGlutamate receptor 2target
DB01483BarbitalGlutamate receptor ionotropic, kainate 2target
DB01483BarbitalCytochrome P450 3A4enzyme
DB01483BarbitalCytochrome P450 2C19enzyme
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-1target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-2target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-3target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-4target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-5target
DB01496Barbituric acid derivativeGamma-aminobutyric acid receptor subunit alpha-6target
DB01496Barbituric acid derivativeNeuronal acetylcholine receptor subunit alpha-4target
DB01496Barbituric acid derivativeNeuronal acetylcholine receptor subunit alpha-7target
DB01496Barbituric acid derivativeGlutamate receptor 2target
DB01496Barbituric acid derivativeGlutamate receptor ionotropic, kainate 2target
DB01227LevacetylmethadolMu-type opioid receptortarget
DB01227LevacetylmethadolCytochrome P450 3A4enzyme
DB01227LevacetylmethadolNeuronal acetylcholine receptor subunit beta-4target
DB01227LevacetylmethadolNeuronal acetylcholine receptor subunit alpha-3target
DB01227LevacetylmethadolCytochrome P450 3A5enzyme
DB01227LevacetylmethadolCytochrome P450 3A7enzyme
DB01227LevacetylmethadolCytochrome P450 19A1enzyme
DB01156BupropionSodium-dependent dopamine transportertarget
DB01156BupropionSodium-dependent noradrenaline transportertarget
DB01156BupropionCytochrome P450 2B6enzyme
DB01156BupropionCytochrome P450 2D6enzyme
DB01156BupropionAlpha-1-acid glycoprotein 1carrier
DB01156BupropionNeuronal acetylcholine receptor subunit alpha-3target
DB01156BupropionCytochrome P450 2A6enzyme
DB01156BupropionCytochrome P450 2C8enzyme
DB01156BupropionCytochrome P450 2C9enzyme
DB01156BupropionCytochrome P450 2E1enzyme
DB01156BupropionCytochrome P450 3A4enzyme
DB01156BupropionSolute carrier family 22 member 2transporter
DB01156Bupropion5-hydroxytryptamine receptor 3Atarget
DB08838AgmatineSolute carrier family 22 member 1transporter
DB08838AgmatineSolute carrier family 22 member 2transporter
DB08838AgmatineSolute carrier family 22 member 3transporter
DB08838AgmatineAlpha-2C adrenergic receptortarget
DB08838AgmatineNischarintarget
DB08838AgmatineAcetylcholine receptor subunit alphatarget
DB08838AgmatineGlutamate receptor ionotropic, NMDA 1target
DB08838AgmatineATP-sensitive inward rectifier potassium channel 1target
DB08838AgmatineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB08838AgmatineAcid-sensing ion channel 3target
DB08838AgmatineY+L amino acid transporter 1transporter
DB08838AgmatineCytochrome P450 3A4enzyme
DB00565CisatracuriumNeuronal acetylcholine receptor subunit alpha-2target
DB05710GantacuriumNeuronal acetylcholine receptor subunit alpha-3target
DB08960HexamethoniumNeuronal acetylcholine receptor subunit alpha-2target
DB00753IsofluraneCalcium-transporting ATPase type 2C member 1target
DB00753IsofluraneATP synthase subunit delta, mitochondrialtarget
DB00753IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB00753IsofluranePotassium voltage-gated channel subfamily A member 1target
DB00753IsofluraneGlutamate receptor 1target
DB00753IsofluraneGlycine receptor subunit alpha-1target
DB00753IsofluraneCalmodulintarget
DB00753IsofluraneCytochrome P450 2E1enzyme
DB00753IsofluraneSerum albumincarrier
DB00753IsofluraneCytochrome P450 2B6enzyme
DB00753IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
DB00753IsofluraneGABA-A receptor (anion channel)target
DB00753IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
DB00753IsofluraneNeuronal acetylcholine receptor subunit beta-2target
DB00915AmantadineD(2) dopamine receptortarget
DB00915AmantadineMatrix protein 2target
DB00915AmantadineAromatic-L-amino-acid decarboxylaseenzyme
DB00915AmantadineAmine oxidase [flavin-containing] Benzyme
DB00915AmantadineSolute carrier family 22 member 2transporter
DB00915AmantadineSolute carrier family 22 member 1transporter
DB00915AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-7target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-4target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineMultidrug resistance protein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target