Spiro Compounds

Name
Spiro Compounds
Accession Number
DBCAT000923
Description

A group of compounds consisting in part of two rings sharing one atom (usually a carbon) in common.

Drugs
DrugDrug Description
BuspironeAn anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression.
FluoresceinA dye used in angiography or angioscopy of the iris and retina.
FluspirileneAn antipsychotic agent used in the treatment of schizophrenia.
Fluorescein lisicolFluorescein lisicol has been used in trials studying the diagnostic of Pharmacokinetics, Hepatic Cirrhosis, Hepatitis, Viral, Human, Nonalcoholic Steatohepatitis, and Non-Alcoholic Fatty Liver Disease.
EosinNot Annotated
Phloxine BFor use in dental disclosing products, allowing for highlighting of bacterial placques.
IrbesartanAn angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
Rose bengalIndicated as a diagnostic agent in routine ocular examinations or when superficial conjunctiva or corneal tissue change is suspected, and as an aid in the diagnosis of keratoconjunctivitis sicca, keratitis,...
Drugs & Drug Targets
DrugTargetType
Buspirone5-hydroxytryptamine receptor 1Atarget
BuspironeDopamine D2 receptortarget
BuspironeCytochrome P450 3A4enzyme
BuspironeCytochrome P450 3A5enzyme
BuspironeCytochrome P450 3A7enzyme
BuspironeP-glycoprotein 1transporter
BuspironeCytochrome P450 2D6enzyme
BuspironeSerum albumincarrier
BuspironeAlpha-1-acid glycoprotein 1carrier
BuspironeDopamine D3 receptortarget
BuspironeDopamine D4 receptortarget
BuspironeAlpha-1 adrenergic receptorstarget
FluoresceinIg kappa chain V-II region RPMI 6410target
FluoresceinDNAtarget
FluoresceinSolute carrier family 22 member 6transporter
FluoresceinBile salt export pumptransporter
FluoresceinMultidrug resistance-associated protein 1transporter
FluspirileneDopamine D2 receptortarget
Fluspirilene5-hydroxytryptamine receptor 2Atarget
FluspirileneVoltage-dependent calcium channel gamma-1 subunittarget
FluspirileneCytochrome P450 3A4enzyme
IrbesartanType-1 angiotensin II receptortarget
IrbesartanTranscription factor AP-1target
IrbesartanCytochrome P450 2C9enzyme
IrbesartanCytochrome P450 2C8enzyme
IrbesartanUDP-glucuronosyltransferase 1-3enzyme
IrbesartanProstaglandin G/H synthase 1enzyme
IrbesartanCytochrome P450 3A4enzyme
IrbesartanSerum albumincarrier
Irbesartanalpha1-acid glycoproteincarrier
Rose bengalSerum albumincarrier
Rose bengalLactotransferrincarrier
Rose bengalSerotransferrincarrier
Rose bengalLysozyme Cenzyme