A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.
DrugDrug NameDrug Description
DB00492FosinoprilAn ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
DB01197CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
DB08847HydroxyprolineUsed in France as a combination product for the treatment of small, superficial wounds.
DB13166ZofenoprilZofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
DB13363OxaceprolNot Annotated
DB14207FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
DB08766ZofenoprilatNot Available
DB00172ProlineAn amino acid commonly found as a component of total parenteral nutrition.
DrugDrug NameTargetType
DB00492FosinoprilAngiotensin-converting enzymetarget
DB00492FosinoprilSolute carrier family 15 member 1transporter
DB00492FosinoprilSolute carrier family 15 member 2transporter
DB01197CaptoprilAngiotensin-converting enzymetarget
DB01197CaptoprilSerum albumincarrier
DB01197Captopril72 kDa type IV collagenasetarget
DB01197CaptoprilMatrix metalloproteinase-9target
DB01197CaptoprilP-glycoprotein 1transporter
DB01197CaptoprilSolute carrier family 15 member 1transporter
DB01197CaptoprilSolute carrier family 22 member 6transporter
DB01197CaptoprilLeukotriene A-4 hydrolasetarget
DB01197CaptoprilB1 bradykinin receptortarget
DB08847HydroxyprolineProton-coupled amino acid transporter 1transporter
DB13166ZofenoprilAngiotensin-converting enzymetarget
DB08766ZofenoprilatCytosol aminopeptidasetarget
DB00172ProlinePyrroline-5-carboxylate reductase 1, mitochondrialtarget
DB00172ProlineBifunctional glutamate/proline--tRNA ligasetarget
DB00172ProlineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)target
DB00172ProlineSodium-dependent proline transportertarget
DB00172ProlinePyrroline-5-carboxylate reductase 2target
DB00172ProlineProlyl 4-hydroxylase subunit alpha-2target
DB00172ProlineProline dehydrogenase 1, mitochondrialtarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Htarget
DB00172ProlineProline synthase co-transcribed bacterial homolog proteintarget
DB00172ProlineProlyl 4-hydroxylase subunit alpha-1target
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Btarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Ctarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Atarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Gtarget
DB00172ProlineProlyl 3-hydroxylase 1target
DB00172ProlinePyrroline-5-carboxylate reductasetarget
DB00172ProlineProbable proline--tRNA ligase, mitochondrialtarget
DB00172ProlineProlyl 3-hydroxylase 2target
DB00172ProlineProlyl 3-hydroxylase 3target
DB00172ProlinePyrroline-5-carboxylate reductase 3target
DB00172ProlineTrans-L-3-hydroxyproline dehydratasetarget
DB00172ProlineProline dehydrogenase 1, mitochondrialenzyme
DB00172ProlineMonocarboxylate transporter 10transporter