|DB00514||Dextromethorphan||For treatment and relief of dry cough.|
|DB00555||Lamotrigine||Indicated as adjunctive therapy for the following seizure types in patients ≥2 years of age: partial seizures/primary generalized tonic-clonic seizures/generalized seizures of Lennox-Gastaut syndrome [FDA Label].
Indicated for conversion to monotherapy in adults (≥16 years of age) with partial seizures who are receiving treatment with carbamazepine, phenytoin, phenobarbital, primidone, or valproate as the single antiepileptic drug (AED)[FDA Label].
Indicated for the maintenance treatment of Bipolar I Disorder to delay the time to occurrence of mood episodes (depression, mania, hypomania, mixed episodes) in adults (≥18 years of age) treated for acute mood episodes with standard therapy [FDA Label].|
|DB00740||Riluzole||For the treatment of amyotrophic lateral sclerosis (ALS, Lou Gehrig's Disease)|
|DB00996||Gabapentin||For the management of postherpetic neuralgia in adults and as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy.|
|DB01043||Memantine||Memantine is used to manage moderate to severe Alzheimer's dementia [FDA label].
A more recent systemic review and meta-analysis [A177106] indicates that memantine is beneficial as a first line drug for the treatment of Alzheimer's dementia. Cholinesterase inhibitors may be added to memantine for further beneficial effects on behavioral symptoms and other symptoms of dementia [A177106].|
|DB01174||Phenobarbital||For the treatment of all types of seizures except absence seizures.|
|DB01221||Ketamine||Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior other general anesthetic agents and as a supplement of low potency agents.[L1336, FDA label]
Reports have indicated a potential use of ketamine as a therapeutic tool for the management of depression when administered in lower doses.[A31873] These reports have increased the interest for ketamine in this area and several clinical trials are launched for this indication.[L1337, A31874]|
|DB06444||Dexanabinol||Investigated for use/treatment in traumatic brain injuries and neurologic disorders.|
|DB06738||Ketobemidone||For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.|
|DB11937||Kynurenic Acid||Not Available|