Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
DrugDrug NameDrug Indication
DB00531CyclophosphamideCyclophosphamide is indicated for the treatment of malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma, and carcinoma of the breast. It is also indicated for the treatment of biopsy-proven minimal change nephrotic syndrome in pediatric patients.
DB04816DantronNot Available
DB09236LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors [L1126].
DB09526HydroquinoneHydroquinone is used as an OTC topical lightening agent for disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots and freckles.
DB11561AminacrineNot Available
DB11989BenznidazoleFor use in the treatment of Chagas disease in children 2-12 years of age [L939].
DB12156CordycepinNot Available
DB12902TrofosfamideNot Available
DB13009CarbendazimNot Available
DB13245ThiramNot Available
DB14015Sodium bisulfiteNot Available
DB14144p-AminophenolNot Available
DB083982-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineNot Available