Phenylpropionates

Name
Phenylpropionates
Accession Number
DBCAT000976
Description

Derivatives of 3-phenylpropionic acid, including its salts and esters.

Drugs
DrugDrug Description
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
OMS-103HPInvestigated for use/treatment in inflammatory disorders (unspecified), knee replacement, orthopedic surgery, and pain (acute or chronic).
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
DexibuprofenFor more information, refer to ibuprofen.
DexketoprofenFor short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache .
Drugs & Drug Targets
DrugTargetType
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenSerum albumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1-1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenSerum albumincarrier
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenSerum albumincarrier
IbuprofenMultidrug resistance-associated protein 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenSolute carrier family 22 member 8transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenP-glycoprotein 1transporter
IbuprofenUDP-glucuronosyltransferase 1-3enzyme
IbuprofenUDP-glucuronosyltransferase 1-9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
OMS-103HPTumor necrosis factortarget
OMS-103HPInterleukin-1 receptor type 1target
DexibuprofenProstaglandin G/H synthase 1target
DexibuprofenProstaglandin G/H synthase 2target
DexibuprofenApoptosis regulator Bcl-2target
DexibuprofenThrombomodulintarget
DexibuprofenTissue-type plasminogen activatortarget
DexibuprofenFatty acid-binding protein, intestinaltarget
DexibuprofenPeroxisome proliferator-activated receptor gammatarget
DexibuprofenCystic fibrosis transmembrane conductance regulatortarget
DexibuprofenCytochrome P450 2C9enzyme
DexibuprofenSerum albumincarrier
DexibuprofenMultidrug resistance-associated protein 4transporter
DexibuprofenMultidrug resistance-associated protein 1transporter
DexibuprofenSolute carrier organic anion transporter family member 1A2transporter
DexibuprofenSolute carrier family 22 member 6transporter
DexibuprofenSolute carrier family 22 member 8transporter
DexibuprofenSolute carrier family 22 member 11transporter
DexibuprofenSolute carrier organic anion transporter family member 2B1transporter
DexibuprofenP-glycoprotein 1transporter
DexibuprofenUDP-glucuronosyltransferase 1-1enzyme
DexibuprofenUDP-glucuronosyltransferase 1-3enzyme
DexibuprofenUDP-glucuronosyltransferase 1-9enzyme
DexibuprofenUDP-glucuronosyltransferase 2B4enzyme
DexibuprofenUDP-glucuronosyltransferase 2B7enzyme
DexibuprofenCytochrome P450 2C8enzyme
DexibuprofenCytochrome P450 2C19enzyme
DexibuprofenSolute carrier family 15 member 1target
DexibuprofenPeroxisome proliferator-activated receptor alphatarget
DexibuprofenPlatelet glycoprotein Ib alpha chaintarget
DexibuprofenProtein S100-A7target
DexibuprofenAlpha-methylacyl-CoA racemaseenzyme
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme