Biopolymers

Polymers synthesized by living organisms. They play a role in the formation of macromolecular structures and are synthesized via the covalent linkage of biological molecules, especially AMINO ACIDS; NUCLEOTIDES; and CARBOHYDRATES.
DrugDrug NameDrug Description
DB00638InulinHistorically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised...
DB00702IcodextrinAn iso-osmotic solution used for continuous peritoneal dialysis or automated peritoneal dialysis.
DB00840Hydroxypropyl celluloseA cellulose ether used to treat dry eyes.
DB00893Iron DextranAn iron supplement used to treat iron deficiency in patients who cannot take oral iron.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB02061CellobioseA disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose. [PubChem]
DB02237MaltotetraoseNot Available
DB02430Trehalose-6-PhosphateNot Available
DB02717CellotetraoseNot Available
DB03323MaltoseA dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing. (Grant & Hackh's Chemical Dictionary, 5th ed)
DB04941CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
DB05899IT-101Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB06206SugammadexA modified gamma cyclodextrin used to reverse neuromuscular blockade induced by vecuronium bromide and rocuronium bromide which are agents used for anesthesia.
DB06423EndostatinInvestigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
DB06776Sodium cellulose phosphateSodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by...
DB08917Ferric carboxymaltoseAn iron replacement therapy used to treat iron deficiency anemia in adults with intolerance or inadequate clinical response to oral iron or those who have non-dialysis dependent chronic kidney disease.
DB09106Hydroxyethyl StarchA plasma volume substitute used to treat and prevent hypovolemia.
DB09111PentastarchA plasma volume expander used as an adjunct in the management of shock due to hemorrhage, surgery, sepsis, burns or other trauma.
DB09255DextranA low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures.
DB09508FerumoxidesNot Annotated
DB10535Karaya gumAn extract from Karaya gum used in allergy testing.
DB10667TragacanthAn extract from Tragacanth used in allergy testing.
DB10852CarobAn extract from Carob used in allergy testing.
DB11059CarboxymethylcelluloseA compound used as an ophthalmic lubricant.
DB11075HypromelloseAn ingredient used in a wide variety of medications, and is not an approved medication.
DB11120TurpentineA medication used to treat minor aches and pains of muscles and joints.
DB11158PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
DB11165RosinRosin is a solid form of resin obtained from pines and other plants, mostly conifers. It is prepared from heating fresh liquid resin to vaporize the volatile liquid terpene components....
DB11223Tolu balsamNot Annotated
DB11228MethylcelluloseA compound used as a bulk forming laxative and is not an approved medication.
DB11234PoliglusamPoliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from...
DB11417GleptoferronColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
DB11482Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
DB11599Starch, cornCorn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides...
DB11602Hydroxyethyl celluloseAn ingredient used in formulations to alleviate irritation of the skin.
DB12310TrehaloseCabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.
DB13128SizofiranA beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. Sizofiran has been used...
DB13446Guar gumNot Annotated
DB13480LentinanNot Annotated
DB13560DextranomerNot Annotated
DB13570Oxidized celluloseNot Annotated
DB14139Hydroxyethyl ethylcelluloseHydroxyethyl ethylcellulose modulates bacterial binding to salivary pellicle; moderately effective in preventing plaque formation.
DB14158Microcrystalline celluloseA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material,...
DB14326AmberAmber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
DB03995BetadexNot Available
DB06496Dextrin 2-sulfateInvestigated for use/treatment in HIV prevention.
DB14836PolydextrosePolydextrose is under investigation in clinical trial NCT02258750 (Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety).
DB14927AmylopectinAmylopectin is under investigation in clinical trial NCT01708694 (Role of Slowly Digesible Starch on Diabetes Risk Factors).
DB15216AmyloseAmylose is under investigation in clinical trial NCT01027325 (Resistant Starch Insulin Sensitivity Trial).
DB15379Hydroxypropyl betadexHydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
DB11727EndostarEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
DB11859BrexanoloneBrexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072].
DB15531Silk sericinNot Annotated
DrugDrug NameTargetType
DB00638InulinCycloinulo-oligosaccharide fructanotransferasetarget
DB00702IcodextrinPancreatic alpha-amylaseenzyme
DB00893Iron DextranHemoglobin subunit betatarget
DB00893Iron DextranHemoglobin subunit alphatarget
DB00893Iron DextranFerritin heavy chaintarget
DB00893Iron DextranFerritin light chaintarget
DB00893Iron DextranSerotransferrincarrier
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB02061CellobioseEndoglucanase Gtarget
DB02061CellobioseEndoglucanase 5Atarget
DB02061CellobioseEndoglucanasetarget
DB02237MaltotetraoseGlucan 1,4-alpha-maltotetraohydrolasetarget
DB02237MaltotetraoseNeopullulanase 2target
DB02430Trehalose-6-PhosphateHTH-type transcriptional regulator TreRtarget
DB02717CellotetraoseCellulose 1,4-beta-cellobiosidasetarget
DB03323MaltoseCyclomaltodextrin glucanotransferasetarget
DB03323MaltoseAlpha-amylase 2Btarget
DB03323MaltoseBeta-amylasetarget
DB03323MaltoseMaltogenic alpha-amylasetarget
DB03323MaltoseMaltodextrin phosphorylasetarget
DB03323MaltoseMaltose-binding periplasmic proteintarget
DB03323MaltoseAlpha-glucosidasetarget
DB03323MaltoseMaltose binding proteintarget
DB03323MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
DB04941CrofelemerCystic fibrosis transmembrane conductance regulatortarget
DB04941CrofelemerAnoctamin-1target
DB06423Endostatin72 kDa type IV collagenasetarget
DB06423EndostatinMatrix metalloproteinase-9target
DB06423EndostatinCollagenase 3target
DB06423EndostatinFocal adhesion kinase 1target
DB06423EndostatinE-selectintarget
DB06423EndostatinCytochrome P450 19A1enzyme
DB06776Sodium cellulose phosphateCalcium ionstarget
DB11059CarboxymethylcelluloseSolute carrier family 2, facilitated glucose transporter member 1target
DB11075HypromelloseEpithelial cell adhesion moleculetarget
DB11120TurpentineMitogen-activated protein kinase 1target
DB03995BetadexNeopullulanase 2target
DB03995BetadexMaltose-binding periplasmic proteintarget
DB03995BetadexMaltogenic amylasetarget
DB11859BrexanoloneGABA-A receptor (anion channel)target
DB11859BrexanoloneAldose reductaseenzyme