Biopolymers

Name
Biopolymers
Accession Number
DBCAT001023
Description

Polymers synthesized by living organisms. They play a role in the formation of macromolecular structures and are synthesized via the covalent linkage of biological molecules, especially AMINO ACIDS; NUCLEOTIDES; and CARBOHYDRATES.

Drugs
DrugDrug Description
InulinHistorically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised...
IcodextrinAn iso-osmotic solution used for continuous peritoneal dialysis or automated peritoneal dialysis.
Hydroxypropyl celluloseA cellulose ether used to treat dry eyes.
Iron DextranAn iron supplement used to treat iron deficiency in patients who cannot take oral iron.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
CellobioseA disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose. [PubChem]
MaltotetraoseNot Available
Trehalose-6-PhosphateNot Available
CellotetraoseNot Available
MaltoseA dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing. (Grant & Hackh's Chemical Dictionary, 5th ed)
CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
IT-101Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
SugammadexA modified gamma cyclodextrin used to reverse neuromuscular blockade induced by vecuronium bromide and rocuronium bromide which are agents used for anesthesia.
EndostatinInvestigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
Sodium cellulose phosphateSodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by...
Ferric carboxymaltoseAn iron replacement therapy used to treat iron deficiency anemia in adults with intolerance or inadequate clinical response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Hydroxyethyl StarchA plasma volume substitute used to treat and prevent hypovolemia.
PentastarchA plasma volume expander used as an adjunct in the management of shock due to hemorrhage, surgery, sepsis, burns or other trauma.
DextranA low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures.
FerumoxidesNot Annotated
Karaya gumAn extract from Karaya gum used in allergy testing.
TragacanthAn extract from Tragacanth used in allergy testing.
CarobAn extract from Carob used in allergy testing.
CarboxymethylcelluloseA compound used as an ophthalmic lubricant.
HypromelloseAn ingredient used in a wide variety of medications, and is not an approved medication.
TurpentineA medication used to treat minor aches and pains of muscles and joints.
PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
RosinAn extract from Rosin used in allergy testing.
Tolu balsamNot Annotated
MethylcelluloseA compound used as a bulk forming laxative and is not an approved medication.
PoliglusamPoliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from...
GleptoferronColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
Starch, cornCorn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides...
Hydroxyethyl celluloseAn ingredient used in formulations to alleviate irritation of the skin.
TrehaloseCabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.
SizofiranA beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. Sizofiran has been used...
Guar gumNot Annotated
LentinanNot Annotated
DextranomerNot Annotated
Oxidized celluloseNot Annotated
Hydroxyethyl ethylcelluloseHydroxyethyl ethylcellulose modulates bacterial binding to salivary pellicle; moderately effective in preventing plaque formation.
Microcrystalline celluloseA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material,...
AmberAmber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
BetadexNot Available
Dextrin 2-sulfateInvestigated for use/treatment in HIV prevention.
PolydextrosePolydextrose is under investigation in clinical trial NCT02258750 (Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety).
AmylopectinAmylopectin is under investigation in clinical trial NCT01708694 (Role of Slowly Digesible Starch on Diabetes Risk Factors).
AmyloseAmylose is under investigation in clinical trial NCT01027325 (Resistant Starch Insulin Sensitivity Trial).
Hydroxypropyl betadexHydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
EndostarEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
BrexanoloneBrexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072].
Silk sericinNot Annotated
AcaciaAn extract from Acacia used in allergy testing.
Drugs & Drug Targets
DrugTargetType
InulinCycloinulo-oligosaccharide fructanotransferasetarget
IcodextrinPancreatic alpha-amylaseenzyme
Iron DextranHemoglobin subunit betatarget
Iron DextranHemoglobin subunit alphatarget
Iron DextranFerritin heavy chaintarget
Iron DextranFerritin light chaintarget
Iron DextranSerotransferrincarrier
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
CellobioseEndoglucanase Gtarget
CellobioseEndoglucanase 5Atarget
CellobioseEndoglucanasetarget
MaltotetraoseGlucan 1,4-alpha-maltotetraohydrolasetarget
MaltotetraoseNeopullulanase 2target
Trehalose-6-PhosphateHTH-type transcriptional regulator TreRtarget
CellotetraoseCellulose 1,4-beta-cellobiosidasetarget
MaltoseCyclomaltodextrin glucanotransferasetarget
MaltoseAlpha-amylase 2Btarget
MaltoseBeta-amylasetarget
MaltoseMaltogenic alpha-amylasetarget
MaltoseMaltodextrin phosphorylasetarget
MaltoseMaltose-binding periplasmic proteintarget
MaltoseAlpha-glucosidasetarget
MaltoseMaltose binding proteintarget
MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
CrofelemerCystic fibrosis transmembrane conductance regulatortarget
CrofelemerAnoctamin-1target
Endostatin72 kDa type IV collagenasetarget
EndostatinMatrix metalloproteinase-9target
EndostatinCollagenase 3target
EndostatinFocal adhesion kinase 1target
EndostatinE-selectintarget
EndostatinCytochrome P450 19A1enzyme
Sodium cellulose phosphateCalcium ionstarget
CarboxymethylcelluloseSolute carrier family 2, facilitated glucose transporter member 1target
HypromelloseEpithelial cell adhesion moleculetarget
TurpentineMitogen-activated protein kinase 1target
BetadexNeopullulanase 2target
BetadexMaltose-binding periplasmic proteintarget
BetadexMaltogenic amylasetarget
BrexanoloneGABA-A receptor (anion channel)target
BrexanoloneAldose reductaseenzyme