QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.
|Drug||Drug Name||Drug Description|
|DB00716||Nedocromil||A pyrano quinoline used to treat allergic conjunctivitis.|
|DB00779||Nalidixic acid||A quinolone antibiotic used to treat urinary tract infections.|
|DB13627||Oxolinic acid||Not Annotated|