Diuretics, Osmotic
- Name
- Diuretics, Osmotic
- Accession Number
- DBCAT001104
- Description
Compounds that increase urine volume by increasing the amount of osmotically active solute in the urine. Osmotic diuretics also increase the osmolarity of plasma.
- Drugs
Drug Drug Description Mannitol A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. Isosorbide A vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. It was previously used to reduce intraocular pressure. Urea A keratolytic emollient used to treat hyperkeratotic lesions and moisturize the skin. - Drugs & Drug Targets
Drug Target Type Mannitol Mannitol dehydrogenase enzyme Isosorbide Guanylate cyclase target Urea Arginase-1 target Urea Carbonic anhydrase 2 target Urea Catenin beta-1 target Urea Sulfoxide reductase catalytic subunit YedY target Urea Urea transporter 2 transporter Urea Urea transporter 1 transporter Urea Dihydrofolate reductase target