beta-Lactamase Inhibitors
- Name
- beta-Lactamase Inhibitors
- Accession Number
- DBCAT001119
- Description
Endogenous substances and drugs that inhibit or block the activity of BETA-LACTAMASES.
- ATC Classification
- Drugs
Drug Drug Description Tazobactam A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. Sulbactam An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Clavulanic acid A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics. Avibactam A non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia. Isatoic anhydride Not Available Relebactam A beta-lactamase inhibitor used to prevent hydrolysis of beta-lactam antibiotics, leading to increased effectiveness. Vaborbactam A beta lactamase inhibitor used to treat complicated urinary tract infections. Levonadifloxacin Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)). Durlobactam A non-beta-lactam, beta-lactamase inhibitor used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. Enmetazobactam A beta-lactamase inhibitor used to treat complicated urinary tract infections in combination with cefepime. - Drugs & Drug Targets