Fatty Acids, Monounsaturated

Fatty acids which are unsaturated in only one position.
DrugDrug NameDrug Indication
DB00770AlprostadilFor palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. Also for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology.
DB01046LubiprostoneFor the treatment of chronic idiopathic constipation in the adult population. Also used for the treatment of irritable bowel syndrome with constipation in women who are 18 years of age or older.
DB01597CilastatinCombined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect.
DB02955Ricinoleic AcidNot Available
DB04224Oleic AcidNot Available
DB04870Oleoyl-estroneFor the treatment of obesity.
DB06689Ethanolamine oleateFor the treatment of patients with esophageal varices that have recently bled, to prevent rebleeding.
DB06774CapsaicinThe capsaicin 8% patch is indicated in the treatment of neuropathic pain associated with post-herpetic neuralgia. There are multiple topical capsaicin formulations available, including creams and solutions, indicated for temporary analgesia in muscle and join pain as well as neuropathic pain.
DB08964GemeprostIndicated for the softening and dilatation of the cervix uteri prior to transcervical, intrauterine operative procedures in the first trimester of pregnancy or facilitating therapeutic termination of pregnancy in patients in the second trimester of gestation.
DB09120ZucapsaicinIndicated to be used in conjunction with oral COX-2 inhibitors or NSAIDs for the relief of severe pain in adult patients with osteoarthritis of the knee, not controlled with oral COX-2 inhibitors or NSAIDs alone, for a duration of no more than three months.
DB09211LimaprostLimaprost is used for the improvement of various ischemic symptoms such as ulcer, pain and feeling of coldness associated with thromboangiitis obliterans as well as improvement of subjective symptoms (pain and numbness of lower legs) and gait ability associated with acquired lumbar spinal canal stenosis (in patients with bilateral intermittent claudication showing normal SLR test result).
DB11117Undecylenic acidIndicated for the treatment of fungal infections as a salt form. No therapeutic indications on its own.
DB11324Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient [L2641], [A32884], [L2642].
DB04801cis-Vaccenic acidNot Available
DB15398DihydrocapsiateNot Available
DrugDrug NameTargetType
DB00770AlprostadilProstaglandin E2 receptor EP2 subtypetarget
DB00770AlprostadilProstaglandin E2 receptor EP1 subtypetarget
DB00770AlprostadilMultidrug resistance-associated protein 5transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2B1transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 3A1transporter
DB00770AlprostadilMultidrug resistance-associated protein 4transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2A1transporter
DB00770AlprostadilProstaglandin D2 receptor 2target
DB00770AlprostadilSolute carrier family 22 member 6transporter
DB01046LubiprostoneChloride channel protein 2target
DB01046LubiprostoneCarbonyl reductase [NADPH] 1enzyme
DB01597CilastatinDipeptidase 1target
DB01597CilastatinSolute carrier family 22 member 6transporter
DB01597CilastatinSolute carrier family 22 member 8transporter
DB02955Ricinoleic AcidCannabinoid receptor 1target
DB02955Ricinoleic AcidCannabinoid receptor 2target
DB02955Ricinoleic AcidTransient receptor potential cation channel subfamily V member 1target
DB04224Oleic AcidFatty acid-binding protein, heartcarrier
DB04224Oleic AcidFatty acid-binding protein, livercarrier
DB04224Oleic AcidSerum albumincarrier
DB04224Oleic AcidVitamin D-binding proteincarrier
DB04224Oleic AcidGlycolipid transfer proteintarget
DB04224Oleic Acid14 kDa fatty acid-binding proteintarget
DB04224Oleic AcidMyelin P2 proteintarget
DB04224Oleic AcidFatty acid-binding protein, braincarrier
DB04224Oleic AcidFatty acid-binding protein, adipocytecarrier
DB04224Oleic AcidPeroxisome proliferator-activated receptor alphatarget
DB04224Oleic AcidPeroxisome proliferator-activated receptor deltatarget
DB04224Oleic AcidRetinoic acid receptor RXR-alphatarget
DB04224Oleic AcidPeroxisome proliferator-activated receptor gammatarget
DB06689Ethanolamine oleateCytochrome P450 2E1enzyme
DB06689Ethanolamine oleateCalcium ionstarget
DB06689Ethanolamine oleateCoagulation factor XIItarget
DB06774CapsaicinCytochrome P450 3A4enzyme
DB06774CapsaicinProstaglandin G/H synthase 2enzyme
DB06774CapsaicinCytochrome P450 1A2enzyme
DB06774CapsaicinCytochrome P450 2E1enzyme
DB06774CapsaicinAmine oxidase [flavin-containing] Aenzyme
DB06774CapsaicinDopamine beta-hydroxylaseenzyme
DB06774CapsaicinGlutamine synthetaseenzyme
DB06774CapsaicinTransient receptor potential cation channel subfamily V member 1target
DB08964GemeprostProstaglandin E2 receptor EP2 subtypetarget
DB08964GemeprostProstaglandin E2 receptor EP3 subtypetarget
DB09120ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
DB09120ZucapsaicinCytochrome P450 1A2enzyme
DB09120ZucapsaicinCytochrome P450 2C19enzyme
DB09120ZucapsaicinCytochrome P450 2C9enzyme
DB09120ZucapsaicinCytochrome P450 2E1enzyme
DB09211LimaprostProstaglandin E2 receptor EP1 subtypetarget
DB09211LimaprostProstaglandin E2 receptor EP2 subtypetarget
DB09211LimaprostProstaglandin E2 receptor EP3 subtypetarget
DB09211LimaprostProstaglandin E2 receptor EP4 subtypetarget
DB11324NonivamideTransient receptor potential cation channel subfamily V member 1target
DB04801cis-Vaccenic acidPeroxisome proliferator-activated receptor deltatarget