ortho-Aminobenzoates

Name
ortho-Aminobenzoates
Accession Number
DBCAT001133
Description

Benzoic acids, salts, or esters that contain an amino group attached to carbon number 2 or 6 of the benzene ring structure.

Drugs
DrugDrug Description
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
3-hydroxyanthranilic acidAn oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
GlafenineAn anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Flufenamic acidAn analgesic drug used to relieve pain associated with rheumatoid diseases.
Niflumic acidA cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
EtofenamateAn NSAID used to treat muscle and joint pain.
MorniflumateAn NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems.
ZapnometinibNot Annotated
Drugs & Drug Targets
DrugTargetType
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidSerum albumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
Mefenamic acidCytochrome P450 1A2enzyme
Mefenamic acidUDP-glucuronosyltransferase 2B7enzyme
3-hydroxyanthranilic acidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidArachidonate 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
Flufenamic acidAldo-keto reductase family 1 member C3target
Flufenamic acidTransthyretincarrier
Flufenamic acidProstaglandin G/H synthase 2target
Flufenamic acidProstaglandin G/H synthase 1target
Flufenamic acidSolute carrier family 22 member 6transporter
Flufenamic acidAndrogen receptortarget
Flufenamic acidPeroxisome proliferator-activated receptor alphatarget
Flufenamic acidPeroxisome proliferator-activated receptor gammatarget
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1-9target
Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
EtofenamateThyroxine-binding globulincarrier
MorniflumateArachidonate 5-lipoxygenasetarget
MorniflumateProstaglandin G/H synthase 2target
MorniflumateArachidonate 5-lipoxygenaseenzyme
MorniflumateProstaglandin G/H synthase 2enzyme
MorniflumateLeukotriene B4 receptor 1target
MorniflumateThromboxane A2 receptortarget
MorniflumateUDP-glucuronosyltransferase 1-9enzyme