Accession Number
DBCAT001158  (DBCAT003732)

Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition.

DrugDrug Description
LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
KaolinA natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding.
PolycarbophilPolycarbophil is used to treat constipation and to help maintain regular bowel movements.
CarobAn extract from Carob used in allergy testing.
OpiumA medication used to treat moderate to severe pain.
RacecadotrilRacecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
DifenoxinAn antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
Calcium polycarbophilA bulk forming laxative used to treat constipation.
Telotristat ethylA tryptophan hydroxylase inhibitor used to treat carcinoid syndrome.
Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
Loperamide oxideNot Annotated
Drugs & Drug Targets
LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
LoperamideMu-type opioid receptortarget
LoperamideDelta-type opioid receptortarget
LoperamideCytochrome P450 3A4enzyme
LoperamideP-glycoprotein 1transporter
LoperamideKappa-type opioid receptortarget
LoperamideCytochrome P450 2C8enzyme
LoperamideCytochrome P450 2B6enzyme
LoperamideCytochrome P450 2D6enzyme
LoperamideNuclear receptor subfamily 1 group I member 3target
DiphenoxylateMu-type opioid receptortarget
DiphenoxylateDelta-type opioid receptortarget
Bismuth subsalicylateSerum albumincarrier
Bismuth subsalicylateSerotransferrincarrier
OpiumDelta-type opioid receptortarget
OpiumKappa-type opioid receptortarget
OpiumMu-type opioid receptortarget
OpiumSerum albumincarrier
OpiumCytochrome P450 2D6enzyme
OpiumCytochrome P450 3A4enzyme
CrofelemerCystic fibrosis transmembrane conductance regulatortarget
Telotristat ethylTryptophan 5-hydroxylase 2target
Telotristat ethylTryptophan 5-hydroxylase 1target
Bismuth subgallateSerum albumincarrier