Chloride Channel Agonists
- Name
- Chloride Channel Agonists
- Accession Number
- DBCAT001249
- Description
A class of drugs that stimulate chloride ion influx through cell membrane channels.
- Drugs
Drug Drug Description Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Ivacaftor A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. Bamocaftor Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis). - Drugs & Drug Targets