- Accession Number
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
Drug Drug Description Tetracosactide A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Corticotropin A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Bremelanotide Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of... Setmelanotide Setmelanotide has been investigated for the treatment of obesity. Alsactide Not Annotated
- Drugs & Drug Targets