Deoxycholic Acid

Name
Deoxycholic Acid
Accession Number
DBCAT001381
Description

A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.

ATC Classification
Drugs
DrugDrug Description
Ursodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients.
Glycochenodeoxycholic AcidA bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed....
Obeticholic acidA bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA.
Chenodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis.
Taurochenodeoxycholic acidTaurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy.
Tauroursodeoxycholic acidUsed in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis,...
Bamet-UD2Bamet-UD2 is a novel bile acid-platinum derivative.
cis-Diamminechlorocholylglycinateplatinum(II)Not Annotated
Deoxycholic acidA cytolytic agent injected subcutaneously to improve the appearance submental fat.
Drugs & Drug Targets
DrugTargetType
Ursodeoxycholic acidAldo-keto reductase family 1 member C2target
Ursodeoxycholic acidBile salt export pumptransporter
Ursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Ursodeoxycholic acidCanalicular multispecific organic anion transporter 1transporter
Ursodeoxycholic acidMultidrug resistance-associated protein 4transporter
Ursodeoxycholic acidIleal sodium/bile acid cotransportertransporter
Ursodeoxycholic acidSodium/bile acid cotransportertransporter
Ursodeoxycholic acidCytochrome P450 2E1enzyme
Ursodeoxycholic acidBile acid receptortarget
Glycochenodeoxycholic Acid7-alpha-hydroxysteroid dehydrogenasetarget
Glycochenodeoxycholic AcidBile salt export pumptransporter
Glycochenodeoxycholic AcidSolute carrier organic anion transporter family member 1A2transporter
Glycochenodeoxycholic AcidIleal sodium/bile acid cotransportertransporter
Glycochenodeoxycholic AcidSodium/bile acid cotransportertransporter
Obeticholic acidBile acid receptortarget
Obeticholic acidCytochrome P450 1A2enzyme
Obeticholic acidBile salt export pumptransporter
Chenodeoxycholic acidBile acid receptortarget
Chenodeoxycholic acidSterol 26-hydroxylase, mitochondrialenzyme
Chenodeoxycholic acidCytochrome P450 3A4enzyme
Chenodeoxycholic acidUDP-glucuronosyltransferase 2B7enzyme
Chenodeoxycholic acidNuclear receptor subfamily 1 group I member 2target
Chenodeoxycholic acidG-protein coupled bile acid receptor 1target
Chenodeoxycholic acidAldo-keto reductase family 1 member C2target
Taurochenodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Taurochenodeoxycholic acidCystine/glutamate transportertransporter
Taurochenodeoxycholic acidCytochrome P450 3A4enzyme
Tauroursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Tauroursodeoxycholic acidCystine/glutamate transportertransporter
Tauroursodeoxycholic acidCytochrome P450 3A1enzyme
Tauroursodeoxycholic acidCytochrome P450 3A2enzyme
Tauroursodeoxycholic acidCytochrome P450 2A1enzyme
Tauroursodeoxycholic acidCytochrome P450 2A2enzyme
Tauroursodeoxycholic acidCytochrome P450 2B1enzyme
Tauroursodeoxycholic acidCytochrome P450 2B2enzyme
Tauroursodeoxycholic acidCytochrome P450 2B9enzyme
Bamet-UD2Solute carrier organic anion transporter family member 1B1transporter
cis-Diamminechlorocholylglycinateplatinum(II)Solute carrier organic anion transporter family member 1B1transporter
Deoxycholic acidBile salt export pumptransporter
Deoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Deoxycholic acidIleal sodium/bile acid cotransportertransporter
Deoxycholic acidSodium/bile acid cotransportertransporter
Deoxycholic acidSteroid Delta-isomerasetarget
Deoxycholic acidPpcAtarget
Deoxycholic acidElongation factor Tu GTP-binding domain-containing protein 1target
Deoxycholic acidCholoylglycine hydrolasetarget
Deoxycholic acidLactaldehyde dehydrogenasetarget
Deoxycholic acidAcriflavine resistance protein Btarget
Deoxycholic acidCytochrome c oxidase subunit 1target
Deoxycholic acidCytochrome c oxidase subunit 2target
Deoxycholic acidBile acid receptortarget
Deoxycholic acidGlutathione S-transferase Ptarget
Deoxycholic acidG-protein coupled bile acid receptor 1target