Pharmaceutical Vehicles

Name
Pharmaceutical Vehicles
Accession Number
DBCAT001429
Description

A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)

Drugs
DrugDrug Description
Hard fatNot Annotated
Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
Propylene glycolA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
TromethamineA proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery.
Octylphenoxy polyethoxyethanolNot Available
TragacanthAn extract from Tragacanth used in allergy testing.
Polysorbate 80It is used as a solubilizer, antimicrobial preservative and disinfectant .
Polysorbate 20Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is...
Poloxamer 407Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,...
Poloxamer 188A medication used to clean wounds.
TricaprylinTricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
TriethylhexanoinTriethylhexanoin is an ingredient of cosmetic products as a fragrant solvent.
Microcrystalline celluloseA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material,...
Hydroxypropyl betadexHydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
BetadexNot Available
Sulfobutylether-beta-cyclodextrinNot Annotated
Drugs & Drug Targets
DrugTargetType
Polyethylene glycolP-glycoprotein 1transporter
Propylene glycolB12-independent glycerol dehydratasetarget
TromethamineAmyloid beta A4 proteintarget
Octylphenoxy polyethoxyethanolTroponin C, skeletal muscletarget
BetadexNeopullulanase 2target
BetadexMaltose-binding periplasmic proteintarget
BetadexMaltogenic amylasetarget