Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
DrugDrug NameDrug Description
DB02261Platelet Activating FactorNot Available
DB03438LysophosphatidylglycerolNot Available
DB04143Indole-3-Glycerol PhosphateNot Available
DB04327PhosphatidylethanolamineNot Available
DB04660Choline alfoscerateA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes...
DB04897LucinactantIntended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS.
DB05456ETC-588Investigated for use/treatment in atherosclerosis, coronary artery disease, and vascular diseases.
DB09114Colfosceril palmitateA pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants.
DB09561Sodium glycerophosphateA medication used to treat hypophosphatemia.
DB11283DL-dimyristoylphosphatidylcholineDL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication.
DB11284DL-dimyristoylphosphatidylglycerolDL-dimyristoylphosphatidylglycerol is not an considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indications.
DB13615MifamurtideA muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection.
DB140991,2-DistearoyllecithinNot Annotated
DB15259VB-201VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
DB11133Omega-3 fatty acidsAn ingredient found in a variety of supplements and vitamins.
DB00144Phosphatidyl serineA nutrient used in some supplement products.
DrugDrug NameTargetType
DB02261Platelet Activating FactorGanglioside GM2 activatortarget
DB02261Platelet Activating FactorP-glycoprotein 1transporter
DB02261Platelet Activating FactorPlatelet-activating factor receptortarget
DB04143Indole-3-Glycerol PhosphateTryptophan synthase alpha chaintarget
DB04143Indole-3-Glycerol PhosphateTryptophan synthase beta chaintarget
DB04327PhosphatidylethanolamineEndothelial protein C receptortarget
DB04327PhosphatidylethanolaminePhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENtarget
DB04660Choline alfoscerateGanglioside GM2 activatortarget
DB13615MifamurtideToll-like receptor 4target
DB13615MifamurtideNucleotide-binding oligomerization domain-containing protein 2target
DB11133Omega-3 fatty acidsPeroxisome proliferator-activated receptor gammatarget
DB11133Omega-3 fatty acidsProstaglandin G/H synthase 2enzyme
DB11133Omega-3 fatty acidsArachidonate 5-lipoxygenaseenzyme
DB11133Omega-3 fatty acidsPeroxisome proliferator-activated receptor alphatarget
DB11133Omega-3 fatty acidsSterol regulatory element-binding protein 1target
DB00144Phosphatidyl serinePhosphatidylserine decarboxylase proenzymetarget
DB00144Phosphatidyl serineScavenger receptor class B member 1target
DB00144Phosphatidyl serineProtein kinase C alpha typetarget
DB00144Phosphatidyl serinePhosphatidylserine synthase 1target
DB00144Phosphatidyl serineDiacylglycerol kinase gammatarget
DB00144Phosphatidyl serineDiacylglycerol kinase deltatarget
DB00144Phosphatidyl serinePhosphatidylserine synthase 2target
DB00144Phosphatidyl serineSphingomyelin phosphodiesterase 4target
DB00144Phosphatidyl serineSphingomyelin phosphodiesterase 3target
DB00144Phosphatidyl serineProbable phospholipid-transporting ATPase IAtarget