Receptors, AMPA, antagonists & inhibitors

Name
Receptors, AMPA, antagonists & inhibitors
Accession Number
DBCAT001477
Description
Not Available
Drugs
DrugDrug Description
2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic AcidNot Available
TalampanelFor the treatment of epilepsy.
TezampanelInvestigated for use/treatment in pain (acute or chronic) and migraine and cluster headaches.
PerampanelA non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.
Drugs & Drug Targets
DrugTargetType
2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic AcidGlutamate receptor 2target
TalampanelGlutamate receptor 1target
TalampanelGlutamate receptor 2target
TalampanelGlutamate receptor 3target
TalampanelGlutamate receptor 4target
TezampanelGlutamate receptor ionotropic, kainate 1target
TezampanelGamma-aminobutyric acid type B receptor subunit 1target
PerampanelGlutamate receptor 1target
PerampanelCytochrome P450 3A4enzyme
PerampanelCytochrome P450 3A5enzyme
PerampanelCytochrome P450 1A2enzyme
PerampanelCytochrome P450 2B6enzyme