Uracil Nucleotides

DrugDrug NameDrug Indication
DB03041UDP-alpha-D-glucuronic acidNot Available
DB03501Galactose-uridine-5'-diphosphateNot Available
DB036681-(5'-Phospho-Beta-D-Ribofuranosyl)Barbituric AcidNot Available
DB037186-Aza-UmpNot Available
DB037615-Fluoro-2'-Deoxyuridine-5'-MonophosphateNot Available
DB03800Deoxyuridine monophosphateNot Available
DB08934SofosbuvirSofosbuvir is used in combination therapy with other antiviral medications to treat chronic hepatitis C virus (HCV) infected patients with HCV genoptypes 1-6, and to treat HCV and HIV co-infected patients. Depending on the level of cirrhosis or decompensation, combination therapy can also include either ribavirin alone or ribavirin and peg-interferon alfa. When used in combination with [DB09027] as the combination product Harvoni, sofosbuvir has the following indications: treatment of genotypes 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis; in combination with [DB00811] for genotype 1 infection with decompensated cirrhosis; or in combination with [DB00811] for the treatment of genotype 1 or 4 infection who are liver transplant recipients without cirrhosis or with compensated cirrhosis. When used in combination with [DB11613] as the combination product Epclusa, sofosbuvir is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) genotypes 1, 2, 3, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis, or in combination with [DB00811] if associated with decompensated cirrhosis. Resistance: Reduced susceptibility to sofosbuvir has been associated with the NS5B substitution mutation S282T [A19634].
DB01861Uridine diphosphate glucoseNot Available
DB027143'-UridinemonophosphateNot Available
DB03685Uridine monophosphateNot Available
DB04005Uridine 5'-triphosphateNot Available
DrugDrug NameTargetType
DB03041UDP-alpha-D-glucuronic acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3target
DB03041UDP-alpha-D-glucuronic acidUDP-glucose 6-dehydrogenasetarget
DB03041UDP-alpha-D-glucuronic acidUDP-glucose 4-epimerasetarget
DB03501Galactose-uridine-5'-diphosphateHisto-blood group ABO system transferasetarget
DB03501Galactose-uridine-5'-diphosphateUDP-glucose 4-epimerasetarget
DB03501Galactose-uridine-5'-diphosphateBeta-1,4-galactosyltransferase 1target
DB036681-(5'-Phospho-Beta-D-Ribofuranosyl)Barbituric AcidOrotidine 5'-phosphate decarboxylasetarget
DB037615-Fluoro-2'-Deoxyuridine-5'-MonophosphateThymidylate synthasetarget
DB037615-Fluoro-2'-Deoxyuridine-5'-MonophosphateThymidylate synthasetarget
DB037615-Fluoro-2'-Deoxyuridine-5'-MonophosphateThymidylate synthase ThyXtarget
DB037615-Fluoro-2'-Deoxyuridine-5'-MonophosphateThymidylate synthase 1target
DB03800Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB03800Deoxyuridine monophosphateThymidylate synthase ThyXtarget
DB03800Deoxyuridine monophosphatePol polyproteintarget
DB03800Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
DB03800Deoxyuridine monophosphateThymidylate synthasetarget
DB08934SofosbuvirMultidrug resistance protein 1transporter
DB08934SofosbuvirATP-binding cassette sub-family G member 2transporter
DB08934SofosbuvirRNA-dependent RNA-polymerasetarget
DB08934SofosbuvirLysosomal protective proteinenzyme
DB08934SofosbuvirCarboxylesteraseenzyme
DB08934SofosbuvirHistidine triad nucleotide-binding protein 1enzyme
DB08934SofosbuvirUMP-CMP kinaseenzyme
DB08934SofosbuvirNucleoside diphosphate kinase Aenzyme
DB01861Uridine diphosphate glucoseGalactose-1-phosphate uridylyltransferasetarget
DB01861Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
DB01861Uridine diphosphate glucoseAlpha,alpha-trehalose-phosphate synthase [UDP-forming]target
DB01861Uridine diphosphate glucoseGlucose-1-phosphate thymidylyltransferasetarget
DB01861Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
DB01861Uridine diphosphate glucoseDNA beta-glucosyltransferasetarget
DB01861Uridine diphosphate glucoseGlycosyltransferase 6 domain-containing protein 1target
DB01861Uridine diphosphate glucoseWbpPtarget
DB01861Uridine diphosphate glucoseGlycogenin-1target
DB027143'-UridinemonophosphateRibonuclease pancreatictarget
DB03685Uridine monophosphateUridine-cytidine kinase-like 1target
DB03685Uridine monophosphateGalactose-1-phosphate uridylyltransferasetarget
DB03685Uridine monophosphateThymidylate synthasetarget
DB03685Uridine monophosphateGlycosyltransferase 6 domain-containing protein 1target
DB03685Uridine monophosphateU6 snRNA-associated Sm-like protein LSm6target
DB03685Uridine monophosphateUracil phosphoribosyltransferasetarget
DB03685Uridine monophosphateBeta-1,4-galactosyltransferase 1target
DB03685Uridine monophosphateInterferon-stimulated gene 20 kDa proteintarget
DB03685Uridine monophosphateOrotidine 5'-phosphate decarboxylasetarget
DB03685Uridine monophosphateBifunctional protein PyrRtarget
DB03685Uridine monophosphateUracil phosphoribosyltransferasetarget
DB03685Uridine monophosphateBifunctional polymyxin resistance protein ArnAtarget
DB03685Uridine monophosphateRibosomal small subunit pseudouridine synthase Atarget
DB04005Uridine 5'-triphosphateUridine-cytidine kinase 2target
DB04005Uridine 5'-triphosphateGenome polyproteintarget
DB04005Uridine 5'-triphosphateGenome polyproteintarget