CCR5 Receptor Antagonists

Name
CCR5 Receptor Antagonists
Accession Number
DBCAT001623
Description

Compounds and drugs that inhibit or block the activity of CCR5 RECEPTORS.

Drugs
DrugDrug Description
MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
CenicrivirocCenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.
AZD-5672Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.
PF-232798PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Drugs & Drug Targets
DrugTargetType
MaravirocC-C chemokine receptor type 5target
MaravirocCytochrome P450 3A4enzyme