Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors

All categories
Name
Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors
Accession Number
DBCAT001628
Description

Not Available

Drugs
DrugDrug Description
RoxadustatA hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to treat symptomatic anemia associated with chronic kidney disease.
DaprodustatA small-molecule hypoxia-inducible factor prolyl hydroxylase inhibitor used for the treatment of anemia in patients with chronic kidney disease.
VadadustatAn oral hypoxia-inducible factor prolyl-hydroxylase inhibitor used to treat symptomatic anemia associated with chronic kidney disease in adults on chronic maintenance dialysis.
Drugs & Drug Targets
DrugTargetType
RoxadustatEgl nine homolog 1target
RoxadustatEgl nine homolog 2target
RoxadustatEgl nine homolog 3target
RoxadustatCytochrome P450 2C8enzyme
RoxadustatATP-binding cassette sub-family G member 2transporter
RoxadustatSolute carrier organic anion transporter family member 1B1transporter
RoxadustatSerum albumincarrier
RoxadustatUDP-glucuronosyltransferase 1-9enzyme
RoxadustatSolute carrier family 22 member 6transporter
RoxadustatSolute carrier family 22 member 8transporter
DaprodustatEgl nine homolog 1target
DaprodustatEgl nine homolog 2target
DaprodustatEgl nine homolog 3target
DaprodustatCytochrome P450 2C8enzyme
DaprodustatCytochrome P450 3A4enzyme
DaprodustatSolute carrier organic anion transporter family member 1B1transporter
DaprodustatSolute carrier organic anion transporter family member 1B3transporter
DaprodustatSolute carrier family 22 member 6transporter
DaprodustatSolute carrier family 22 member 8transporter
DaprodustatATP-binding cassette sub-family G member 2transporter
VadadustatEgl nine homolog 2target
VadadustatEgl nine homolog 3target
VadadustatEgl nine homolog 1target
VadadustatHypoxia-inducible factor 1-alphatarget
VadadustatEndothelial PAS domain-containing protein 1target
VadadustatUDP-glucuronosyltransferase 1-1enzyme
VadadustatUDP-glucuronosyltransferase 1-7enzyme
VadadustatUDP-glucuronosyltransferase 1-8enzyme
VadadustatUDP-glucuronosyltransferase 1-9enzyme
VadadustatUDP-glucuronosyltransferase 2B7enzyme
VadadustatCytochrome P450 2B6enzyme
VadadustatCytochrome P450 2C8enzyme
VadadustatCytochrome P450 3A4enzyme
VadadustatATP-binding cassette sub-family G member 2transporter
VadadustatSolute carrier family 22 member 8transporter
VadadustatSolute carrier family 22 member 6transporter
VadadustatSerum albumincarrier
VadadustatCytochrome P450 2C9enzyme