Phospholipase A2 Inhibitors

Name
Phospholipase A2 Inhibitors
Accession Number
DBCAT001741
Description

Compounds that inhibit or block the activity of a PHOSPHOLIPASE A2 enzyme.

Drugs
DrugDrug Description
Varespladib methylInvestigated for use/treatment in atherosclerosis and coronary artery disease.
DarapladibInvestigated for use/treatment in atherosclerosis.
VarespladibVarespladib has been investigated for the treatment and prevention of Sickle Cell Disease, Vaso-occlusive Crisis, and Acute Coronary Syndrome.
Drugs & Drug Targets
DrugTargetType
Varespladib methylPhospholipase A2, membrane associatedtarget
Varespladib methylGroup 10 secretory phospholipase A2target
DarapladibCytosolic phospholipase A2target