Radiopharmaceuticals

Name
Radiopharmaceuticals
Accession Number
DBCAT001840
Description

Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)

Drugs
DrugDrug Description
IobenguaneA radiopharmaceutical agent used for the diagnosis of primary and metastatic pheochromocytoma or neuroblastoma.
Technetium Tc-99m mebrofeninA diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests.
Technetium Tc-99m medronateA diagnostic radiopharmaceutical agent used as a bone imaging agent to delineate areas of altered osteogenesis.
Technetium Tc-99m sestamibiA radiopharmaceutical diagnostic agent used in nuclear medicine imaging tests to detect coronary artery disease and evaluate myocardial function.
Technetium Tc-99m exametazimeA radiopharmaceutical diagnostic agent used as an adjunct for scintigraphy in the detection of altered regional cerebral perfusion in stroke.
Technetium Tc-99m disofeninA radiopharmaceutical diagnostic agent used for hepatobiliary scans.
Technetium Tc-99m pyrophosphateA radiopharmaceutical diagnostic agent used for diagnostic imaging scans for the bones, heart, and gastrointestinal tract.
Technetium Tc-99m pertechnetateA radiocontrast agent used for the identification of various organs, including but not limited to the brain, thyroid, placenta, and bladder.
Technetium Tc-99m sulfur colloidA radiopharmaceutical diagnostic agent used for the localization of lymph nodes, evaluation of peritoneovenous (LeVeen) shunt patency, imaging areas of functioning reticuloendothelial cells, and gastrointestinal imaging.
Iofetamine I-123Not Annotated
Fludeoxyglucose (18F)A radiopharmaceutical agent used for positron emission tomography (PET) imaging in oncology, cardiology, and neurology.
PentetreotidePentetreotide has been used in trials studying the diagnostic of cushing syndrome.
BesilesomabA monoclonal antibody bound to technetium-99 used to find infection and inflammation in patients with suspected osteomyelitis.
PyrithioneAn antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis.
Flutemetamol (18F)A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment.
Technetium Tc-99m tetrofosminTechnetium-99m tetrofosmin is indicated for the diagnosis of heart abnormalities by exercise myocardial scintigraphy. The exercise myocardial scintigraphy is an established method for the diagnosis of the severity of coronary...
Bevacizumab zirconium Zr-89Bevacizumab zirconium Zr-89 is under investigation in clinical trial NCT01338090 (89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors).
FlutemetamolFlutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).
Fluoroazomycin arabinoside F-18Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer).
Edotreotide gallium Ga-68A radioactive diagnostic agent used in PET scans for somatostatin receptor positive neuroendocrine tumors in adult and pediatric patients.
Drugs & Drug Targets
DrugTargetType
IobenguaneSodium-dependent noradrenaline transportertransporter
Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B1transporter
Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B3transporter
Technetium Tc-99m sestamibiP-glycoprotein 1transporter
Technetium Tc-99m sestamibiMultidrug resistance-associated protein 1transporter
Technetium Tc-99m pyrophosphateHydroxyapatitetarget
Technetium Tc-99m pyrophosphateAmorphous calcium phosphatetarget
Fludeoxyglucose (18F)Hexokinase-1enzyme
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 4transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 2transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 1transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 3transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 9transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 5transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 6transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 7transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 8transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 10transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 11transporter
Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 12transporter
BesilesomabCarcinoembryonic antigentarget
Flutemetamol (18F)Amyloid beta A4 proteintarget
Technetium Tc-99m tetrofosminP-glycoprotein 1carrier
Edotreotide gallium Ga-68Somatostatin receptor type 2target
Edotreotide gallium Ga-68Somatostatin receptor type 1target
Edotreotide gallium Ga-68Somatostatin receptor type 5target
Edotreotide gallium Ga-68Somatostatin receptor type 3target