Bis-Trimethylammonium Compounds

Name
Bis-Trimethylammonium Compounds
Accession Number
DBCAT001922
Description

Compounds containing polymethylene bis-trimethylammonium cations. Members of this group frequently act as ganglionic blockers and neuromuscular depolarizing agents.

Drugs
DrugDrug Description
HexafluroniumUsed as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations.
DecamethoniumFor use as a skeletal muscle relaxant
HexamethoniumA nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been...
DecamethoxineNot Annotated
Drugs & Drug Targets
DrugTargetType
HexafluroniumCholinesterasetarget
DecamethoniumNeuronal acetylcholine receptor subunit alpha-2target
DecamethoniumAcetylcholinesterasetarget
DecamethoniumCholinesteraseenzyme
DecamethoniumNeuronal acetylcholine receptor subunit alpha-4target
DecamethoniumNeuronal acetylcholine receptor subunit beta-2target
HexamethoniumNeuronal acetylcholine receptor subunit alpha-2target