Blood Substitutes
- Name
- Blood Substitutes
- Accession Number
- DBCAT001950
- Description
Substances that can function like HEMOGLOBINS in the capacity to carry oxygen to and carbon dioxide away from the tissues when introduced into the blood stream. The best known are the perfluorocarbon emulsions.
- Drugs
Drug Drug Description Hemoglobin crosfumaril Hemoglobin in which the alpha-subunit are cross-linked intramolecularly. Perfluorodecalin Perfluorodecalin is under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh... Hydroxyethyl Starch A plasma volume substitute used to treat and prevent hypovolemia. Pentastarch A plasma volume expander used as an adjunct in the management of shock due to hemorrhage, surgery, sepsis, burns or other trauma. Dextran A low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures. Povidone When in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns. Plasma protein fraction (human) A plasma protein solution used to treat coagulation factor deficiencies, reverse anticoagulant effects, and shock from a loss of plasma fluids, and is also used in plasma exchange procedures. Polygeline A medication used for plasma volume expansion. Hemoximer Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight. - Drugs & Drug Targets
Drug Target Type