|DB09067||Corticorelin ovine triflutate||Corticorelin is indicated for use in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.|
|DB00183||Pentagastrin||Used as a diagnostic aid for evaluation of gastric acid secretory function|
|DB00272||Betazole||For use clinically to test gastric secretory function.|
|DB00345||Aminohippuric acid||Used to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.|
|DB00403||Ceruletide||Caerulein is used in the treatment of paralytic ileus and as diagnostic aid in pancreatic malfunction.|
|DB00522||Bentiromide||Indicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.|
|DB00638||Inulin||Historically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised by hyperglycemia and/or hyperinsulinemia.|
|DB00693||Fluorescein||For diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.|
|DB01011||Metyrapone||Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function. Occasionally used in Cushing's syndrome.|
|DB01124||Tolbutamide||For treatment of NIDDM (non-insulin-dependent diabetes mellitus) in conjunction with diet and exercise.|
|DB05381||Histamine||Histamine phosphate is indicated as a diagnostic aid for evaluation of gastric acid secretory function.|
|DB05394||Corticorelin||Investigated for use/treatment in brain cancer and neurologic disorders.|
|DB08862||Cholecystokinin||For use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency [L1634].|
|DB09142||Sincalide||As the product Kinevac (FDA), sincalide is used for the following indications: 1) to stimulate gallbladder contraction, as may be assessed by various methods of diagnostic imaging, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals; (2) to stimulate pancreatic secretion (especially in conjunction with secretin) prior to obtaining a duodenal aspirate for analysis of enzyme activity, composition, and cytology; (3) to accelerate the transit of a barium meal through the small bowel, thereby decreasing the time and extent of radiation associated with fluoroscopy and x-ray examination of the intestinal tract.|
|DB09241||Methylene blue||Indicated for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Other clinical applications of methylene blue include improvement of hypotension associated with various clinical states, an antiseptic in urinary tract infections, treatment of hypoxia and hyperdynamic circulation in cirrhosis of liver and severe hepatopulmonary syndrome, and treatment of ifofosamide induced neurotoxicity.|
|DB11182||Rose bengal free acid||Indicated as a diagnostic agent in routine ocular examinations or when superficial conjunctiva or corneal tissue change is suspected, and as an aid in the diagnosis of keratoconjunctivitis sicca, keratitis, abrasions or corrosions as well as the detection of foreign bodies.|
|DB11577||Indigotindisulfonic Acid||This drug was initially used as a kidney function test. The main application of indigo carmine at this time is localizing and visualizing ureteral orifices during cystoscopy and ureteral catheterization procedures [L2215]. |
|DB13074||Macimorelin||Indicated for the diagnosis of adult growth hormone deficiency (AGHD) [FDA Label].|
|DB00010||Sermorelin||For the treatment of dwarfism, prevention of HIV-induced weight loss|
|DB00162||Vitamin A||For the treatment of vitamin A deficiency.|
|DB00201||Caffeine||For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.|
|DB00644||Gonadorelin||For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.|
|DB00653||Magnesium sulfate||Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.|
|DB01638||Sorbitol||Used as a non-stimulant laxative via an oral suspension or enema.|
|DB03793||Benzoic Acid||Not Available|
|DB11735||Galactose||There are limited therapeutic uses for which galactose is formally indicated. Some predominant indications include (a) the use of galactose to facilitate the construction of structurally and immunologically effective attenuated vaccines [T188, L2633], and (b) the role galactose plays as an essential element in the formation of lactulose - a synthetic disaccharide indicated for the treatment of constipation and/or hepatic encephalopathy (HE); hepatic coma [L2632].
Nevertheless, there are many studies looking into a variety of possible uses for galactose, including the use of the monosaccharide sugar for accelerating senescence in mice, rats, and Drosophila [A32853, A32854], the proposed association between galactose in consumed milk and ovarian cancer [A32855, A32856], a possible role in the therapy of focal segmental glomerulosclerosis [A32858], among various others. Regardless, none of these proposed indications have yet been formally elucidated for practical use.|
|DB09532||Secretin human||Indicated for the stimulation of:
- pancreatic secretions, including bicarbonate, to aid in the diagnosis of pancreatic exocrine dysfunction [FDA Label].
- gastrin secretion to aid in the diagnosis of gastrinoma [FDA Label].
- pancreatic secretions to facilitate the identification of the ampulla of Vater and accessory papilla during endoscopic retrograde cholangiopancreatography (ERCP) [FDA Label].|