Diagnostic Agents

DrugDrug NameDrug Description
DB09067Corticorelin ovine triflutateA synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.
DB00183PentagastrinA gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors.
DB00272BetazoleFor use clinically to test gastric secretory function.
DB00345Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
DB00403CeruletideCaerulein is used in the treatment of paralytic ileus and as diagnostic aid in pancreatic malfunction.
DB00522BentiromideIndicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
DB00638InulinHistorically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised...
DB00693FluoresceinA dye used in angiography or angioscopy of the iris and retina.
DB01011MetyraponeA steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
DB01124TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
DB05381HistamineAn ingredient of topical drugs for the relief of joint pain or muscle aches and pains.
DB05394CorticorelinInvestigated for use/treatment in brain cancer and neurologic disorders.
DB08862CholecystokininFor use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency .
DB09142SincalideA diagnostic agent used to stimulate gallbladder contraction or pancreatic secretion during diagnostic tests, and accelerate fluoroscopy and x-ray examination of the intestinal tract.
DB09241Methylene blueAn oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
DB09421ProtirelinA synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland.
DB11182Rose bengalIndicated as a diagnostic agent in routine ocular examinations or when superficial conjunctiva or corneal tissue change is suspected, and as an aid in the diagnosis of keratoconjunctivitis sicca, keratitis,...
DB11577Indigotindisulfonic acidA medication used to visualize ureteral orifices during cystoscopy and ureteral catheterization.
DB12656SomatorelinSomatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.
DB13074MacimorelinA medication used to treat adult growth hormone deficiency.
DB13212PhenolsulfonphthaleinPhenolsulfonphthalein or otherwise called phenol red is a pH indicator commonly used in cell biology laboratories. Phenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions...
DB13215SulfobromophthaleinSulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans .
DB13298AlsactideNot Annotated
DB00010SermorelinFor the treatment of dwarfism, prevention of HIV-induced weight loss
DB00162Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
DB00201CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
DB00644GonadorelinA synthetic GnRH used to test the function of gonadotropes and the pituitary.
DB00653Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
DB01638SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
DB03793Benzoic acidAn antimicrobial food additive.
DB11735GalactoseThere are limited therapeutic uses for which galactose is formally indicated. Some predominant indications include (a) the use of galactose to facilitate the construction of structurally and immunologically effective attenuated...
DB09532Secretin humanA secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts.
DB15263ThyrotropinThyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human Myometrium).
DrugDrug NameTargetType
DB09067Corticorelin ovine triflutateCorticotropin-releasing factor receptor 1target
DB00183PentagastrinGastrin/cholecystokinin type B receptortarget
DB00183PentagastrinCholinesteraseenzyme
DB00272BetazoleHistamine H2 receptortarget
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00403CeruletideCholecystokinin receptor type Atarget
DB00522BentiromideSerine protease hepsintarget
DB00638InulinCycloinulo-oligosaccharide fructanotransferasetarget
DB00693FluoresceinIg kappa chain V-II region RPMI 6410target
DB00693FluoresceinDNAtarget
DB00693FluoresceinSolute carrier family 22 member 6transporter
DB00693FluoresceinBile salt export pumptransporter
DB00693FluoresceinMultidrug resistance-associated protein 1transporter
DB01011MetyraponeCamphor 5-monooxygenasetarget
DB01011MetyraponeCytochrome P450 11B2, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2A6enzyme
DB01011MetyraponeCytochrome P450 3A4enzyme
DB01011MetyraponeCanalicular multispecific organic anion transporter 2transporter
DB01011MetyraponeCytochrome P450 11B1, mitochondrialtarget
DB01011MetyraponeCytochrome P450 11B1, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2E1enzyme
DB01124TolbutamideATP-sensitive inward rectifier potassium channel 1target
DB01124TolbutamideCytochrome P450 2C19enzyme
DB01124TolbutamideCytochrome P450 2C9enzyme
DB01124TolbutamideCytochrome P450 2C8enzyme
DB01124TolbutamideATP-binding cassette sub-family C member 8target
DB01124TolbutamideSolute carrier family 15 member 1transporter
DB01124TolbutamideSolute carrier organic anion transporter family member 1A2transporter
DB01124TolbutamideSolute carrier family 15 member 2transporter
DB01124TolbutamideSolute carrier family 22 member 6transporter
DB01124TolbutamideSolute carrier organic anion transporter family member 2B1transporter
DB01124TolbutamideCytochrome P450 2C18enzyme
DB01124TolbutamideSerum albumincarrier
DB05381HistamineHistamine H1 receptortarget
DB05381HistamineHistamine H2 receptortarget
DB05381HistamineHistamine H3 receptortarget
DB05381HistamineHistamine N-methyltransferaseenzyme
DB05381HistamineSolute carrier family 22 member 2transporter
DB05381HistamineSolute carrier family 22 member 1transporter
DB05381HistamineSolute carrier family 22 member 3transporter
DB05381HistamineSolute carrier family 22 member 5transporter
DB05381HistamineHistamine H4 receptortarget
DB05381HistamineSynaptic vesicular amine transportertarget
DB05394CorticorelinDopamine beta-hydroxylaseenzyme
DB08862CholecystokininSolute carrier organic anion transporter family member 1B3transporter
DB08862CholecystokininCholecystokinin receptor type Atarget
DB08862CholecystokininRAF proto-oncogene serine/threonine-protein kinasetarget
DB08862CholecystokininMitogen-activated protein kinase 3target
DB08862CholecystokininPro-epidermal growth factortarget
DB08862CholecystokininProtein kinase C beta typetarget
DB08862CholecystokininGastrin/cholecystokinin type B receptortarget
DB08862CholecystokininSolute carrier organic anion transporter family member 1B1transporter
DB08862CholecystokininSolute carrier organic anion transporter family member 2B1transporter
DB09142SincalideSolute carrier organic anion transporter family member 1B3transporter
DB09241Methylene blueGuanylate cyclase soluble subunit alpha-2target
DB09241Methylene blueNitric oxide synthase, braintarget
DB09421ProtirelinThyrotropin Releasing Hormone Receptortarget
DB11182Rose bengalSerum albumincarrier
DB11182Rose bengalLactotransferrincarrier
DB11182Rose bengalSerotransferrincarrier
DB11182Rose bengalLysozyme Cenzyme
DB11577Indigotindisulfonic acidAryl hydrocarbon receptortarget
DB11577Indigotindisulfonic acidAlpha adrenergic receptortarget
DB13074MacimorelinGrowth hormone secretagogue receptor type 1target
DB13074MacimorelinCytochrome P450 3A4enzyme
DB00010SermorelinGrowth hormone-releasing hormone receptortarget
DB00162Vitamin ARetinol dehydrogenase 12target
DB00162Vitamin ARetinol-binding protein 1target
DB00162Vitamin A11-cis retinol dehydrogenasetarget
DB00162Vitamin ARetinol dehydrogenase 13target
DB00162Vitamin ARetinol-binding protein 3target
DB00162Vitamin ARetinol-binding protein 5carrier
DB00162Vitamin ARetinoid-binding protein 7carrier
DB00162Vitamin ARetinol-binding protein 4carrier
DB00162Vitamin ARetinol-binding protein 2carrier
DB00162Vitamin ARetinal dehydrogenase 2target
DB00162Vitamin ARetinal dehydrogenase 1target
DB00162Vitamin ARetinaldehyde-binding protein 1target
DB00162Vitamin ALecithin retinol acyltransferasetarget
DB00162Vitamin AShort-chain dehydrogenase/reductase 3target
DB00162Vitamin AAldehyde dehydrogenase family 1 member A3target
DB00162Vitamin AAll-trans-retinol 13,14-reductasetarget
DB00162Vitamin ARetinol dehydrogenase 11target
DB00162Vitamin ADehydrogenase/reductase SDR family member 4target
DB00162Vitamin ARetinol dehydrogenase 14target
DB00162Vitamin ARetinol dehydrogenase 8target
DB00162Vitamin ACytochrome P450 26A1enzyme
DB00162Vitamin AApolipoprotein Dtarget
DB00162Vitamin AHematopoietic prostaglandin D synthasetarget
DB00162Vitamin ASerum albumincarrier
DB00201CaffeineAdenosine receptor A1target
DB00201CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00201CaffeineAdenosine receptor A2atarget
DB00201CaffeineCytochrome P450 1A2enzyme
DB00201CaffeineRyanodine receptor 1target
DB00201CaffeineCytochrome P450 3A4enzyme
DB00201CaffeineCytochrome P450 2E1enzyme
DB00201CaffeineCytochrome P450 2C8enzyme
DB00201CaffeineCytochrome P450 2C9enzyme
DB00201CaffeineCytochrome P450 1A1enzyme
DB00201CaffeineCytochrome P450 1B1enzyme
DB00201CaffeineCytochrome P450 2D6enzyme
DB00201CaffeineCyclic nucleotide phosphodiesterasetarget
DB00201CaffeineDNA-dependent protein kinase catalytic subunittarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
DB00201CaffeineInositol 1,4,5-trisphosphate receptortarget
DB00201CaffeineSerine-protein kinase ATMtarget
DB00201CaffeineATP-binding cassette sub-family G member 2transporter
DB00201CaffeineAdenosine receptor A2btarget
DB00201CaffeineAdenosine receptor A3target
DB00201CaffeinePhosphodiesterase enzymestarget
DB00644GonadorelinGonadotropin-releasing hormone receptortarget
DB00644GonadorelinPutative gonadotropin-releasing hormone II receptortarget
DB00653Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
DB00653Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolMalate synthase Gtarget
DB03793Benzoic acidPeroxiredoxin-5, mitochondrialtarget
DB03793Benzoic acidHeat-labile enterotoxin B chaintarget
DB03793Benzoic acidCocaine esterasetarget
DB03793Benzoic acidHTH-type transcriptional regulator MalTtarget
DB03793Benzoic acidTautomerase PptAtarget
DB03793Benzoic acidD-amino-acid oxidasetarget
DB03793Benzoic acidRibonuclease UK114target
DB03793Benzoic acidChlorocatechol 1,2-dioxygenasetarget
DB03793Benzoic acidRas-related protein Rab-9Atarget
DB03793Benzoic acidHydrogen peroxide-inducible genes activatortarget
DB03793Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03793Benzoic acidNon-heme chloroperoxidasetarget
DB03793Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
DB03793Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
DB03793Benzoic acidReplication proteintarget
DB03793Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
DB03793Benzoic acidSolute carrier family 22 member 8transporter
DB03793Benzoic acidMonocarboxylate transporter 1transporter
DB03793Benzoic acidSolute carrier family 15 member 1target
DB09532Secretin humanSecretin receptortarget