Diagnostic Agents

Name
Diagnostic Agents
Accession Number
DBCAT002094
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
Corticorelin ovine triflutateA synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.
PentagastrinA gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors.
BetazoleFor use clinically to test gastric secretory function.
Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
CeruletideCaerulein is used in the treatment of paralytic ileus and as diagnostic aid in pancreatic malfunction.
BentiromideIndicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
InulinHistorically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised...
FluoresceinA dye used in angiography or angioscopy of the iris and retina.
MetyraponeA steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
HistamineAn ingredient of topical drugs for the relief of joint pain or muscle aches and pains.
CorticorelinInvestigated for use/treatment in brain cancer and neurologic disorders.
CholecystokininFor use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency .
SincalideA diagnostic agent used to stimulate gallbladder contraction or pancreatic secretion during diagnostic tests, and accelerate fluoroscopy and x-ray examination of the intestinal tract.
Methylene blueAn oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
ProtirelinA synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland.
Rose bengalIndicated as a diagnostic agent in routine ocular examinations or when superficial conjunctiva or corneal tissue change is suspected, and as an aid in the diagnosis of keratoconjunctivitis sicca, keratitis,...
Indigotindisulfonic acidA medication used to visualize ureteral orifices during cystoscopy and ureteral catheterization.
SomatorelinSomatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.
MacimorelinA medication used to treat adult growth hormone deficiency.
PhenolsulfonphthaleinPhenolsulfonphthalein or otherwise called phenol red is a pH indicator commonly used in cell biology laboratories. Phenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions...
SulfobromophthaleinSulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans .
AlsactideNot Annotated
SermorelinFor the treatment of dwarfism, prevention of HIV-induced weight loss
Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
GonadorelinA synthetic GnRH used to test the function of gonadotropes and the pituitary.
Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
Benzoic acidAn antimicrobial food additive.
GalactoseThere are limited therapeutic uses for which galactose is formally indicated. Some predominant indications include (a) the use of galactose to facilitate the construction of structurally and immunologically effective attenuated...
Secretin humanA secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts.
ThyrotropinThyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human Myometrium).
Sodium phosphate P 32Not Annotated
PerflexaneNot Annotated
Drugs & Drug Targets
DrugTargetType
Corticorelin ovine triflutateCorticotropin-releasing factor receptor 1target
PentagastrinGastrin/cholecystokinin type B receptortarget
PentagastrinCholinesteraseenzyme
BetazoleHistamine H2 receptortarget
Aminohippuric acidSolute carrier family 22 member 2transporter
Aminohippuric acidSolute carrier family 22 member 5transporter
Aminohippuric acidSolute carrier family 22 member 6transporter
Aminohippuric acidSolute carrier family 22 member 8transporter
Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 4transporter
Aminohippuric acidSolute carrier family 22 member 11transporter
Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
Aminohippuric acidMultidrug resistance-associated protein 1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
Aminohippuric acidMonocarboxylate transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 7transporter
CeruletideCholecystokinin receptor type Atarget
BentiromideSerine protease hepsintarget
InulinCycloinulo-oligosaccharide fructanotransferasetarget
FluoresceinIg kappa chain V-II region RPMI 6410target
FluoresceinDNAtarget
FluoresceinSolute carrier family 22 member 6transporter
FluoresceinBile salt export pumptransporter
FluoresceinMultidrug resistance-associated protein 1transporter
MetyraponeCamphor 5-monooxygenasetarget
MetyraponeCytochrome P450 11B2, mitochondrialenzyme
MetyraponeCytochrome P450 2A6enzyme
MetyraponeCytochrome P450 3A4enzyme
MetyraponeCanalicular multispecific organic anion transporter 2transporter
MetyraponeCytochrome P450 11B1, mitochondrialtarget
MetyraponeCytochrome P450 11B1, mitochondrialenzyme
MetyraponeCytochrome P450 2E1enzyme
TolbutamideATP-sensitive inward rectifier potassium channel 1target
TolbutamideCytochrome P450 2C19enzyme
TolbutamideCytochrome P450 2C9enzyme
TolbutamideCytochrome P450 2C8enzyme
TolbutamideATP-binding cassette sub-family C member 8target
TolbutamideSolute carrier family 15 member 1transporter
TolbutamideSolute carrier organic anion transporter family member 1A2transporter
TolbutamideSolute carrier family 15 member 2transporter
TolbutamideSolute carrier family 22 member 6transporter
TolbutamideSolute carrier organic anion transporter family member 2B1transporter
TolbutamideCytochrome P450 2C18enzyme
TolbutamideSerum albumincarrier
HistamineHistamine H1 receptortarget
HistamineHistamine H2 receptortarget
HistamineHistamine H3 receptortarget
HistamineHistamine N-methyltransferaseenzyme
HistamineSolute carrier family 22 member 2transporter
HistamineSolute carrier family 22 member 1transporter
HistamineSolute carrier family 22 member 3transporter
HistamineSolute carrier family 22 member 5transporter
HistamineHistamine H4 receptortarget
HistamineSynaptic vesicular amine transportertarget
CorticorelinDopamine beta-hydroxylaseenzyme
CholecystokininSolute carrier organic anion transporter family member 1B3transporter
CholecystokininCholecystokinin receptor type Atarget
CholecystokininRAF proto-oncogene serine/threonine-protein kinasetarget
CholecystokininMitogen-activated protein kinase 3target
CholecystokininPro-epidermal growth factortarget
CholecystokininProtein kinase C beta typetarget
CholecystokininGastrin/cholecystokinin type B receptortarget
CholecystokininSolute carrier organic anion transporter family member 1B1transporter
CholecystokininSolute carrier organic anion transporter family member 2B1transporter
SincalideSolute carrier organic anion transporter family member 1B3transporter
Methylene blueGuanylate cyclase soluble subunit alpha-2target
Methylene blueNitric oxide synthase, braintarget
Methylene blueUDP-glucuronosyltransferase 1-4enzyme
Methylene blueUDP-glucuronosyltransferase 1-9enzyme
Methylene blueCytochrome P450 1A2enzyme
Methylene blueCytochrome P450 2B6enzyme
Methylene blueCytochrome P450 2C8enzyme
Methylene blueCytochrome P450 2C9enzyme
Methylene blueCytochrome P450 2C19enzyme
Methylene blueCytochrome P450 3A4enzyme
Methylene blueCytochrome P450 3A5enzyme
Methylene blueSerum albumincarrier
Methylene blueP-glycoprotein 1transporter
Methylene blueSolute carrier family 22 member 2transporter
Methylene blueMultidrug and toxin extrusion protein 2transporter
Methylene blueMultidrug and toxin extrusion protein 1transporter
Methylene blueFlavin reductase (NADPH)enzyme
Methylene blueCytochrome P450 2D6enzyme
ProtirelinThyrotropin Releasing Hormone Receptortarget
Rose bengalSerum albumincarrier
Rose bengalLactotransferrincarrier
Rose bengalSerotransferrincarrier
Rose bengalLysozyme Cenzyme
Indigotindisulfonic acidAryl hydrocarbon receptortarget
Indigotindisulfonic acidAlpha adrenergic receptortarget
MacimorelinGrowth hormone secretagogue receptor type 1target
MacimorelinCytochrome P450 3A4enzyme
SermorelinGrowth hormone-releasing hormone receptortarget
Vitamin ARetinol dehydrogenase 12target
Vitamin A11-cis retinol dehydrogenasetarget
Vitamin ARetinol dehydrogenase 13target
Vitamin ARetinol-binding protein 5carrier
Vitamin ARetinoid-binding protein 7carrier
Vitamin ARetinol-binding protein 4carrier
Vitamin ARetinol-binding protein 2carrier
Vitamin ARetinal dehydrogenase 2target
Vitamin ARetinal dehydrogenase 1target
Vitamin ALecithin retinol acyltransferasetarget
Vitamin AShort-chain dehydrogenase/reductase 3target
Vitamin AAldehyde dehydrogenase family 1 member A3target
Vitamin AAll-trans-retinol 13,14-reductasetarget
Vitamin ARetinol dehydrogenase 11target
Vitamin ADehydrogenase/reductase SDR family member 4target
Vitamin ARetinol dehydrogenase 14target
Vitamin ARetinol dehydrogenase 8target
Vitamin ACytochrome P450 26A1enzyme
Vitamin AApolipoprotein Dtarget
Vitamin AProstaglandin-H2 D-isomerasetarget
Vitamin ASerum albumincarrier
Vitamin ARetinaldehyde-binding protein 1carrier
Vitamin ARetinol-binding protein 3carrier
Vitamin ARetinol-binding protein 1carrier
Vitamin AReceptor for retinol uptake STRA6transporter
CaffeineAdenosine receptor A1target
CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
CaffeineAdenosine receptor A2atarget
CaffeineCytochrome P450 1A2enzyme
CaffeineRyanodine receptor 1target
CaffeineCytochrome P450 3A4enzyme
CaffeineCytochrome P450 2E1enzyme
CaffeineCytochrome P450 2C8enzyme
CaffeineCytochrome P450 2C9enzyme
CaffeineCytochrome P450 1A1enzyme
CaffeineCytochrome P450 1B1enzyme
CaffeineCytochrome P450 2D6enzyme
CaffeineCyclic nucleotide phosphodiesterasetarget
CaffeineDNA-dependent protein kinase catalytic subunittarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
CaffeineInositol 1,4,5-trisphosphate receptortarget
CaffeineSerine-protein kinase ATMtarget
CaffeineATP-binding cassette sub-family G member 2transporter
CaffeineAdenosine receptor A2btarget
CaffeineAdenosine receptor A3target
CaffeinePhosphodiesterase enzymestarget
GonadorelinGonadotropin-releasing hormone receptortarget
GonadorelinPutative gonadotropin-releasing hormone II receptortarget
Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
SorbitolXylose isomerasetarget
SorbitolXylose isomerasetarget
SorbitolXylose isomerasetarget
SorbitolMalate synthase Gtarget
Benzoic acidPeroxiredoxin-5, mitochondrialtarget
Benzoic acidHeat-labile enterotoxin B chaintarget
Benzoic acidCocaine esterasetarget
Benzoic acidHTH-type transcriptional regulator MalTtarget
Benzoic acidTautomerase PptAtarget
Benzoic acidD-amino-acid oxidasetarget
Benzoic acidRibonuclease UK114target
Benzoic acidChlorocatechol 1,2-dioxygenasetarget
Benzoic acidRas-related protein Rab-9Atarget
Benzoic acidHydrogen peroxide-inducible genes activatortarget
Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
Benzoic acidNon-heme chloroperoxidasetarget
Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
Benzoic acidReplication proteintarget
Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
Benzoic acidSolute carrier family 22 member 8transporter
Benzoic acidMonocarboxylate transporter 1transporter
Benzoic acidSolute carrier family 15 member 1target
Secretin humanSecretin receptortarget