Platelet Aggregation Inhibitors Excl. Heparin

DrugDrug NameDrug Description
DB00054AbciximabA monoclonal anti-glycoprotein IIb/IIIa receptor antibody used to prevent thrombosis during percutaneous coronary intervention.
DB00063EptifibatideA peptide-based antagonist for glycoprotein IIb/IIIa used in the medical management of myocardial infarction and as an adjunct to percutaneous coronary intervention.
DB00208TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
DB00374TreprostinilA prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
DB00758ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
DB00775TirofibanA platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome.
DB00975DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
DB01088IloprostA synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH).
DB01166CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
DB01240EpoprostenolA vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure.
DB05229BeraprostFor the treatment of pulmonary hypertension.
DB06209PrasugrelA P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI.
DB06441CangrelorA P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST).
DB08814TriflusalTriflusal is indicated as prophylaxis of thromboembolic disorders. It has been registered in Spain and in other countries of Europe, South America and South Korea for the prevention of Stroke...
DB08816TicagrelorA P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.
DB08994DitazoleDitazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone. Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade...
DB09030VorapaxarA platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD).
DB11362SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
DB12545IndobufenIndobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.
DB13327PicotamideNot Annotated
DB13367CloricromenNot Annotated
DB13509AloxiprinNot Annotated
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB13612Carbaspirin calciumNot Annotated
DrugDrug NameTargetType
DB00054AbciximabIntegrin beta-3target
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00054AbciximabComplement C1r subcomponenttarget
DB00054AbciximabComplement C1q subcomponent subunit Atarget
DB00054AbciximabComplement C1q subcomponent subunit Btarget
DB00054AbciximabComplement C1q subcomponent subunit Ctarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00054AbciximabComplement C1s subcomponenttarget
DB00054AbciximabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00054AbciximabIntegrin alpha-IIbtarget
DB00054AbciximabVitronectintarget
DB00063EptifibatideIntegrin beta-3target
DB00208TiclopidineP2Y purinoceptor 12target
DB00208TiclopidineCytochrome P450 2C19enzyme
DB00208TiclopidineCytochrome P450 2B6enzyme
DB00208TiclopidineCytochrome P450 2C9enzyme
DB00208TiclopidineCytochrome P450 2D6enzyme
DB00208TiclopidineMyeloperoxidaseenzyme
DB00208TiclopidineCytochrome P450 1A2enzyme
DB00208TiclopidineCytochrome P450 2C8enzyme
DB00208TiclopidineCytochrome P450 2E1enzyme
DB00374TreprostinilP2Y purinoceptor 12target
DB00374TreprostinilPeroxisome proliferator-activated receptor deltatarget
DB00374TreprostinilProstacyclin receptortarget
DB00374TreprostinilCytochrome P450 2C9enzyme
DB00758ClopidogrelP2Y purinoceptor 12target
DB00758ClopidogrelCytochrome P450 3A4enzyme
DB00758ClopidogrelCytochrome P450 2B6enzyme
DB00758ClopidogrelCytochrome P450 3A5enzyme
DB00758ClopidogrelCytochrome P450 2C19enzyme
DB00758ClopidogrelCytochrome P450 2C9enzyme
DB00758ClopidogrelCytochrome P450 1A2enzyme
DB00758ClopidogrelCytochrome P450 2C8enzyme
DB00758ClopidogrelLiver carboxylesterase 1enzyme
DB00758ClopidogrelP-glycoprotein 1transporter
DB00758ClopidogrelSolute carrier family 22 member 1transporter
DB00758ClopidogrelSolute carrier family 22 member 2transporter
DB00775TirofibanIntegrin alpha-IIbtarget
DB00775TirofibanIntegrin beta-3target
DB00975DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB00975DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00975DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00975DipyridamoleAdenosine deaminasetarget
DB00975DipyridamoleMultidrug resistance-associated protein 4transporter
DB00975DipyridamoleMultidrug resistance-associated protein 5transporter
DB00975DipyridamoleP-glycoprotein 1transporter
DB00975DipyridamoleCalcipressin-1target
DB00975DipyridamoleAlpha-1-acid glycoprotein 1target
DB00975DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DB00975DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DB00975DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DB00975DipyridamoleBile salt export pumptransporter
DB01088IloprostProstacyclin receptortarget
DB01088IloprostTissue-type plasminogen activatortarget
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01088IloprostSolute carrier organic anion transporter family member 2B1transporter
DB01088IloprostSolute carrier organic anion transporter family member 2A1transporter
DB01088IloprostSolute carrier organic anion transporter family member 3A1transporter
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01088IloprostProstaglandin E2 receptor EP1 subtypetarget
DB01088IloprostProstaglandin D2 receptor 2target
DB01166CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01166CilostazolCytochrome P450 2C19enzyme
DB01166CilostazolCytochrome P450 3A4enzyme
DB01166CilostazolCytochrome P450 3A5enzyme
DB01166CilostazolCytochrome P450 3A7enzyme
DB01166CilostazolCytochrome P450 1A2enzyme
DB01166CilostazolCytochrome P450 2D6enzyme
DB01240EpoprostenolP2Y purinoceptor 12target
DB01240EpoprostenolProstacyclin receptortarget
DB01240EpoprostenolProstacyclin synthasetarget
DB05229BeraprostProstacyclin receptortarget
DB05229BeraprostCytochrome P450 2C8enzyme
DB06209PrasugrelP2Y purinoceptor 12target
DB06209PrasugrelCocaine esteraseenzyme
DB06209PrasugrelCytochrome P450 3A4enzyme
DB06209PrasugrelCytochrome P450 2B6enzyme
DB06209PrasugrelCytochrome P450 2C9enzyme
DB06209PrasugrelCytochrome P450 2C19enzyme
DB06209PrasugrelSerum albumincarrier
DB06441CangrelorP2Y purinoceptor 12target
DB08814TriflusalProstaglandin G/H synthase 1target
DB08814TriflusalNuclear factor NF-kappa-B p105 subunittarget
DB08814TriflusalNitric oxide synthase, inducibletarget
DB08814TriflusalcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB08814TriflusalSerum albumincarrier
DB08816TicagrelorCytochrome P450 3A4enzyme
DB08816TicagrelorP2Y purinoceptor 12target
DB08816TicagrelorP-glycoprotein 1transporter
DB08816TicagrelorCytochrome P450 2D6enzyme
DB08816TicagrelorCytochrome P450 2C9enzyme
DB09030VorapaxarProteinase-activated receptor 1target
DB09030VorapaxarCytochrome P450 3A4enzyme
DB09030VorapaxarCytochrome P450 2J2enzyme
DB11362SelexipagProstacyclin receptortarget
DB11362SelexipagLiver carboxylesterase 1enzyme
DB11362SelexipagCytochrome P450 2C8enzyme
DB11362SelexipagCytochrome P450 3A4enzyme
DB11362SelexipagSolute carrier organic anion transporter family member 1B1transporter
DB11362SelexipagSolute carrier organic anion transporter family member 1B3transporter
DB11362SelexipagP-glycoprotein 1transporter
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter