Preparations for Treatment of Wounds and Ulcers

DrugDrug NameDrug Indication
DB00048Collagenase clostridium histolyticumUsed to promote debridement of necrotic tissue in the treatment of severe burns and dermal ulcers including decubitus ulcers.
DB00102BecaplerminFor topical treatment of skin ulcers (from diabetes)
DB08818Hyaluronic acidUsed to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical therapy. Hyaluronic acid may also be used in plastic surgery to reduce wrinkles on the face or as a filler in other parts of the body. May be used in ophthalmology to assist in the extraction of cataracts, the implantation of intraocular lenses, corneal transplants, glaucoma filtration, retinal attachment and in the treatment of dry eyes. Finally, hyaluronic acid is also used to coat the bladder lining in treating interstitial cystitis.
DB11237TrypsinNot Available
DB13089EnoxoloneNot Available
DB13210Sodium chloriteNot Available
DB13281BromelainsNot Available
DB13560DextranomerNot Available
DB13747TrolamineTrolamine is used as an alkalizing agent, surfactant, and counter-ion in cosmetic and pharmaceutical formulations [A27174]. It is not considered to be an active pharmacological ingredient and so has no official indication.
DB01783Pantothenic acidStudied for the treatment of many uses such as treatment of testicular torsion, diabetic ulceration, wound healing, acne, obesity, diabetic peripheral polyneuropathy. It has also been investigated for its hypolipidemic effects and as cholesterol lowering agent.
DB09357DexpanthenolInjection: Prophylactic use immediately after major abdominal surgery to minimize the possibility of paralytic ileus. Intestinal atony causing abdominal distention; postoperative or postpartum retention of flatus, or postoperative delay in resumption of intestinal motility; paralytic ileus. Topical: This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e.g., diaper rash, skin burns from radiation therapy).