Preparations for Treatment of Wounds and Ulcers

Name
Preparations for Treatment of Wounds and Ulcers
Accession Number
DBCAT002134
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
Collagenase clostridium histolyticumA collagenase enzyme used to promote debridement of necrotic tissue in burns and skin ulcers as well as to treat Dupuytren's contracture and Peyronie's disease.
BecaplerminA recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area.
Hyaluronic acidA glycosaminoglycan used for the relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications.
TrypsinA naturally occurring proteolytic enzyme found in the digestive tract of mammals. Used clinically in combination with bromelain and rutosides in the treatment of some inflammatory conditions.
EnoxoloneEnoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME).
Sodium chloriteUsed as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food...
BromelainsA protease indicated in the treatment of inflammation and for eschar removal.
DextranomerNot Annotated
TrolamineTrolamine is used as an alkalizing agent, surfactant, and counter-ion in cosmetic and pharmaceutical formulations . It is not considered to be an active pharmacological ingredient and so has no...
Pantothenic acidA vitamin B5 found in various nutritional supplements.
DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
Cadexomer iodineNot Annotated
TraferminInvestigated for use/treatment in coronary artery disease, peripheral vascular disease, periodontal disease, bone fractures, entero-related fistulae, and diabetic foot ulcers.
Drugs & Drug Targets
DrugTargetType
Collagenase clostridium histolyticumCollagen alpha-1(I) chaintarget
Collagenase clostridium histolyticumCollagen alpha-1(II) chaintarget
Collagenase clostridium histolyticumCollagen alpha-1(III) chaintarget
BecaplerminPlatelet-derived growth factor receptor betatarget
BecaplerminAlpha-2-macroglobulintarget
BecaplerminPlatelet-derived growth factor receptor alphatarget
Hyaluronic acidCD44 antigentarget
Hyaluronic acidIntercellular adhesion molecule 1target
Hyaluronic acidHyaluronan mediated motility receptortarget
Hyaluronic acidNeurocan core proteintarget
Hyaluronic acidVersican core proteintarget
Hyaluronic acidComplement component 1 Q subcomponent-binding protein, mitochondrialtarget
Hyaluronic acidHyaluronan and proteoglycan link protein 1target
Hyaluronic acidHyaluronan and proteoglycan link protein 3target
Hyaluronic acidHyaluronan-binding protein 2target
Hyaluronic acidLayilintarget
Hyaluronic acidStabilin-2target
Hyaluronic acidTumor necrosis factor-inducible gene 6 proteintarget
Hyaluronic acidInterphotoreceptor matrix proteoglycan 2target
Hyaluronic acidIntracellular hyaluronan-binding protein 4target
Hyaluronic acidHyaluronidase enzymesenzyme
Hyaluronic acidMultidrug resistance-associated protein 5transporter
Hyaluronic acidLymphatic vessel endothelial hyaluronic acid receptor 1target
Pantothenic acidPantothenate kinasetarget