Angiotensin II Antagonists and Calcium Channel Blockers

Name
Angiotensin II Antagonists and Calcium Channel Blockers
Accession Number
DBCAT002170
Description
Not Available
Drugs
DrugDrug Description
OlmesartanAn angiotensin receptor blocker (ARB) used in the treatment of hypertension.
ValsartanAn angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
AmlodipineA calcium channel blocker used to treat hypertension and angina.
Drugs & Drug Targets
DrugTargetType
OlmesartanType-1 angiotensin II receptortarget
OlmesartanCanalicular multispecific organic anion transporter 1transporter
OlmesartanSolute carrier organic anion transporter family member 1B3transporter
OlmesartanSolute carrier organic anion transporter family member 1B1transporter
OlmesartanBile salt export pumptransporter
ValsartanType-1 angiotensin II receptortarget
ValsartanCytochrome P450 2C9enzyme
ValsartanSolute carrier organic anion transporter family member 1B3transporter
ValsartanSolute carrier organic anion transporter family member 1B1transporter
ValsartanCanalicular multispecific organic anion transporter 1transporter
AmlodipineCarbonic anhydrase 1target
AmlodipineCytochrome P450 3A4enzyme
AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AmlodipineCytochrome P450 1A1enzyme
AmlodipineCytochrome P450 2B6enzyme
AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
AmlodipineCytochrome P450 3A5enzyme
AmlodipineP-glycoprotein 1transporter
AmlodipineCytochrome P450 2C8enzyme
AmlodipineCytochrome P450 2D6enzyme
AmlodipineSphingomyelin phosphodiesterasetarget
AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmlodipineVoltage-dependent N-type calcium channeltarget