Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors

Name
Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors
Accession Number
DBCAT002190
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
PenciclovirA topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.
CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
FamciclovirA nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.
ValaciclovirAn guanine nucleoside antiviral used to treat herpes exacerbations.
ValganciclovirAn antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS).
VidarabineAn antiviral agent used to treat various viral infections.
IdoxuridineA pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
GanciclovirA DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.
BrivudineBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Drugs & Drug Targets
DrugTargetType
PenciclovirDNA polymerase catalytic subunittarget
PenciclovirThymidine kinasetarget
CidofovirDNA polymerase catalytic subunittarget
CidofovirSolute carrier family 22 member 6transporter
CidofovirThymidine phosphorylaseenzyme
FamciclovirDNA polymerase catalytic subunittarget
FamciclovirAldehyde oxidaseenzyme
ValaciclovirThymidine kinasetarget
ValaciclovirDNA polymerase catalytic subunittarget
ValaciclovirSolute carrier family 15 member 1transporter
ValaciclovirSolute carrier family 15 member 2transporter
ValaciclovirSolute carrier family 22 member 8transporter
ValaciclovirSolute carrier family 22 member 6transporter
ValaciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
ValaciclovirIleal sodium/bile acid cotransportertransporter
ValaciclovirGuanylate kinaseenzyme
ValaciclovirThymidine kinaseenzyme
ValganciclovirDNAtarget
ValganciclovirSolute carrier family 15 member 1transporter
ValganciclovirSolute carrier family 15 member 2transporter
ValganciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
VidarabineDNA polymerase catalytic subunittarget
VidarabineThymidine kinasetarget
VidarabineThymidine kinasetarget
VidarabineAdenosine deaminaseenzyme
IdoxuridineThymidine kinasetarget
IdoxuridineDNAtarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirThymidine kinasetarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirSolute carrier family 22 member 8transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirSerum albumincarrier
GanciclovirDNA polymerase catalytic subunittarget
GanciclovirThymidine kinasetarget
GanciclovirSolute carrier family 22 member 1transporter
GanciclovirSolute carrier family 22 member 6transporter
GanciclovirSolute carrier family 22 member 8transporter
GanciclovirSolute carrier family 22 member 7transporter
GanciclovirDNAtarget
GanciclovirMultidrug and toxin extrusion protein 1transporter
GanciclovirMultidrug and toxin extrusion protein 2transporter
BrivudineThymidine kinase 2, mitochondrialtarget
BrivudineDNA polymerasetarget
BrivudineThymidine kinasetarget