Muscle Relaxants, Peripherally Acting Agents

DrugDrug NameDrug Description
DB01336MetocurineMetocurine is a muscle relaxant.
DB00042Botulinum Toxin Type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
DB00083Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
DB00202SuccinylcholineA depolarizing skeletal muscle relaxant used as an adjunct to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures.
DB00565CisatracuriumA skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation.
DB00728RocuroniumA vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.
DB00941HexafluroniumUsed as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations.
DB01135DoxacuriumA nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures.
DB01199TubocurarineA neuromuscular blocker used for the diagnosis of and facilitation of intubation after induction of anesthesia during surgical procedures.
DB01226MivacuriumA short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation.
DB01337PancuroniumA neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
DB01338PipecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles during anesthesia and surgical procedures.
DB01339VecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures.
DB13295AtracuriumNot Annotated
DB13584GallamineNot Annotated
DB13648AlcuroniumA non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
DB13745Fazadinium bromideNot Annotated
DB05710GantacuriumInvestigated for use/treatment in anesthesia (unspecified).
DB08960HexamethoniumA nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been...
DB00181BaclofenA GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients.
DrugDrug NameTargetType
DB01336MetocurineNeuronal acetylcholine receptor subunit alpha-2target
DB01336MetocurineMuscarinic acetylcholine receptor M2target
DB00042Botulinum Toxin Type BVesicle-associated membrane protein 1target
DB00042Botulinum Toxin Type BVesicle-associated membrane protein 2target
DB00042Botulinum Toxin Type BSynaptotagmin-2target
DB00083Botulinum toxin type ASynaptosomal-associated protein 25target
DB00083Botulinum toxin type ARho-related GTP-binding protein RhoBtarget
DB00202SuccinylcholineMuscarinic acetylcholine receptor M1target
DB00202SuccinylcholineCholinesteraseenzyme
DB00202SuccinylcholineMuscarinic acetylcholine receptor M2target
DB00202SuccinylcholineMuscarinic acetylcholine receptor M3target
DB00202SuccinylcholineAlpha-7 nicotinic cholinergic receptor subunittarget
DB00202SuccinylcholineNeuronal acetylcholine receptor subunit alpha-10target
DB00565CisatracuriumNeuronal acetylcholine receptor subunit alpha-2target
DB00728RocuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB00728RocuroniumMuscarinic acetylcholine receptor M2target
DB00728Rocuronium5-hydroxytryptamine receptor 3Atarget
DB00728RocuroniumSolute carrier family 22 member 1transporter
DB00728RocuroniumSolute carrier organic anion transporter family member 1A2transporter
DB00941HexafluroniumCholinesterasetarget
DB01135DoxacuriumNeuronal acetylcholine receptor subunit alpha-2target
DB01135DoxacuriumMuscarinic acetylcholine receptor M2target
DB01135DoxacuriumCholinesteraseenzyme
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
DB01199TubocurarineAcetylcholinesterasetarget
DB01199Tubocurarine5-hydroxytryptamine receptor 3Atarget
DB01199TubocurarineSolute carrier family 22 member 1transporter
DB01199TubocurarineSolute carrier family 22 member 2transporter
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
DB01199TubocurarineCholinesteraseenzyme
DB01226MivacuriumNeuronal acetylcholine receptor subunit alpha-2target
DB01226MivacuriumMuscarinic acetylcholine receptor M2target
DB01226MivacuriumMuscarinic acetylcholine receptor M3target
DB01226MivacuriumCholinesterasetarget
DB01337PancuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB01337PancuroniumCholinesteraseenzyme
DB01337PancuroniumMuscarinic acetylcholine receptor M2target
DB01337PancuroniumMuscarinic acetylcholine receptor M3target
DB01337PancuroniumSolute carrier family 22 member 1transporter
DB01337PancuroniumSolute carrier family 22 member 2transporter
DB01338PipecuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB01338PipecuroniumMuscarinic acetylcholine receptor M2target
DB01338PipecuroniumMuscarinic acetylcholine receptor M3target
DB01338PipecuroniumCholinesteraseenzyme
DB01339VecuroniumP-glycoprotein 1transporter
DB01339VecuroniumNeuronal acetylcholine receptor subunit alpha-2target
DB05710GantacuriumNeuronal acetylcholine receptor subunit alpha-3target
DB08960HexamethoniumNeuronal acetylcholine receptor subunit alpha-2target
DB00181BaclofenGamma-aminobutyric acid type B receptor subunit 1target
DB00181BaclofenGamma-aminobutyric acid type B receptor subunit 2target