Urologicals

Name
Urologicals
Accession Number
DBCAT002207
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
AlfuzosinAn alpha-1 adrenergic antagonist used in the management of benign prostatic hypertrophy (BPH).
DarifenacinAn M3 muscarinic receptor blocker used to treat urinary incontinence.
Acetohydroxamic acidA synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract.
Pentosan polysulfateA sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.
TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
AlprostadilA medication used to treat erectile dysfunction.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
TolterodineA muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.
OxybutyninAn antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
DutasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
FlavoxateA muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia.
TerazosinAn alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension.
Calcium chlorideAn ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate.
FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
PhenazopyridineA local anesthetic used for the symptomatic relief of pain, burning, urgency, frequency, and general discomfort caused by lower urinary tract irritations that are a result of infection, trauma, surgery, endoscopic procedures, or the passage of equipment or catheters.
SolifenacinA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
DapoxetineFor the treatment of premature ejaculation.
SilodosinAn alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH).
AvanafilA phosphodiesterase 5 (PDE5) inhibitor used to treat erectile dysfunction.
UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
FesoterodineAn antimuscarinic agent used in the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
MirabegronA beta-3 adrenergic agonist used to treat urge urinary incontinence, urinary frequency and urgency associated with overactive bladder (OAB).
Magnesium hydroxideAn inorganic compound used as a laxative and antacid.
MoxisylyteBy the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either by...
Phenyl salicylatePain and fever .
PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
MeladrazineNot Annotated
SuccinimideNot Annotated
EmeproniumNot Annotated
TerodilineNot Annotated
ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
Dimethyl sulfoxideA reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
Ammonium chlorideExpectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...
MepartricinNot Annotated
TioproninA thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DesfesoterodineDesfesoterodine is a metabolite of tolterodine.
Drugs & Drug Targets
DrugTargetType
TrospiumMuscarinic acetylcholine receptor M1target
TrospiumCytochrome P450 2D6enzyme
TrospiumMuscarinic acetylcholine receptor M3target
AlfuzosinAlpha-1A adrenergic receptortarget
AlfuzosinAlpha-1B adrenergic receptortarget
AlfuzosinAlpha-1D adrenergic receptortarget
AlfuzosinCytochrome P450 3A4enzyme
AlfuzosinPotassium voltage-gated channel subfamily H member 2target
DarifenacinMuscarinic acetylcholine receptor M3target
DarifenacinCytochrome P450 3A4enzyme
DarifenacinCytochrome P450 2D6enzyme
DarifenacinMuscarinic acetylcholine receptor M1target
DarifenacinMuscarinic acetylcholine receptor M2target
DarifenacinMuscarinic acetylcholine receptor M4target
DarifenacinMuscarinic acetylcholine receptor M5target
Acetohydroxamic acidUrease subunit alphatarget
Acetohydroxamic acidMacrophage metalloelastasetarget
Pentosan polysulfateFibroblast growth factor 1target
Pentosan polysulfateFibroblast growth factor 4target
Pentosan polysulfateFibroblast growth factor 2target
TamsulosinAlpha-1A adrenergic receptortarget
TamsulosinAlpha-1D adrenergic receptortarget
TamsulosinAlpha-1B adrenergic receptortarget
TamsulosinAlpha-1-acid glycoprotein 1carrier
TamsulosinCytochrome P450 2D6enzyme
TamsulosinCytochrome P450 3A4enzyme
AlprostadilProstaglandin E2 receptor EP2 subtypetarget
AlprostadilProstaglandin E2 receptor EP1 subtypetarget
AlprostadilMultidrug resistance-associated protein 5transporter
AlprostadilSolute carrier organic anion transporter family member 2B1transporter
AlprostadilSolute carrier organic anion transporter family member 3A1transporter
AlprostadilMultidrug resistance-associated protein 4transporter
AlprostadilSolute carrier organic anion transporter family member 2A1transporter
AlprostadilProstaglandin D2 receptor 2target
AlprostadilSolute carrier family 22 member 6transporter
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilCytochrome P450 3A5enzyme
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilP-glycoprotein 1transporter
TolterodineMuscarinic acetylcholine receptor M1target
TolterodineMuscarinic acetylcholine receptor M2target
TolterodineMuscarinic acetylcholine receptor M3target
TolterodineCytochrome P450 2D6enzyme
TolterodineCytochrome P450 3A4enzyme
TolterodineCytochrome P450 2C9enzyme
TolterodineCytochrome P450 2C19enzyme
TolterodineMuscarinic acetylcholine receptor M4target
TolterodineMuscarinic acetylcholine receptor M5target
OxybutyninMuscarinic acetylcholine receptor M1target
OxybutyninMuscarinic acetylcholine receptor M2target
OxybutyninMuscarinic acetylcholine receptor M3target
OxybutyninCytochrome P450 3A4enzyme
OxybutyninCytochrome P450 2C8enzyme
OxybutyninCytochrome P450 2D6enzyme
OxybutyninCytochrome P450 3A5enzyme
OxybutyninAlpha-1-acid glycoprotein 1carrier
OxybutyninSerum albumincarrier
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DutasterideSodium-dependent dopamine transportertransporter
DutasterideSynaptic vesicular amine transportertransporter
DutasterideSerum albumincarrier
DutasterideAlpha-1-acid glycoprotein 1carrier
DutasterideCytochrome P450 3A5enzyme
FlavoxateMuscarinic acetylcholine receptor M1target
FlavoxateMuscarinic acetylcholine receptor M2target
TerazosinAlpha-1A adrenergic receptortarget
TerazosinAlpha-1B adrenergic receptortarget
TerazosinAlpha-1D adrenergic receptortarget
TerazosinPotassium voltage-gated channel subfamily H member 2target
TerazosinPotassium voltage-gated channel subfamily H member 6target
TerazosinPotassium voltage-gated channel subfamily H member 7target
TerazosinP-glycoprotein 1transporter
TerazosinTransforming growth factor beta-1target
Calcium chlorideProtein S100-A13target
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
FinasterideCytochrome P450 3A4enzyme
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
FinasterideCytochrome P450 3A5enzyme
FinasterideCytochrome P450 3A7enzyme
FinasterideSolute carrier family 12 member 5transporter
YohimbineAlpha-2A adrenergic receptortarget
YohimbineAlpha-2B adrenergic receptortarget
YohimbineAlpha-2C adrenergic receptortarget
Yohimbine5-hydroxytryptamine receptor 1Atarget
Yohimbine5-hydroxytryptamine receptor 1Btarget
Yohimbine5-hydroxytryptamine receptor 1Dtarget
YohimbineDopamine D2 receptortarget
YohimbineDopamine D3 receptortarget
Yohimbine5-hydroxytryptamine receptor 2Atarget
Yohimbine5-hydroxytryptamine receptor 2Ctarget
YohimbineCytochrome P450 2D6enzyme
YohimbineCytochrome P450 3A4enzyme
YohimbineATP-sensitive potassium channeltarget
Yohimbine5-hydroxytryptamine receptor 2Btarget
PhenazopyridineSodium channel protein type 1 subunit alphatarget
PhenazopyridineGroup A nerve fiberstarget
SolifenacinMuscarinic acetylcholine receptor M3target
SolifenacinMuscarinic acetylcholine receptor M1target
SolifenacinCytochrome P450 3A4enzyme
SolifenacinMuscarinic acetylcholine receptor M2target
SolifenacinMuscarinic acetylcholine receptor M4target
SolifenacinMuscarinic acetylcholine receptor M5target
Solifenacinalpha1-acid glycoproteincarrier
SolifenacinCytochrome P450 1A1enzyme
SolifenacinCytochrome P450 2D6enzyme
Dapoxetine5-hydroxytryptamine receptor 1Atarget
Dapoxetine5-hydroxytryptamine receptor 1Btarget
Dapoxetine5-hydroxytryptamine receptor 2Ctarget
DapoxetineCytochrome P450 3A4enzyme
DapoxetineCytochrome P450 2D6enzyme
SilodosinAlpha-1D adrenergic receptortarget
SilodosinCytochrome P450 3A4enzyme
SilodosinP-glycoprotein 1transporter
SilodosinMultidrug resistance protein 3transporter
SilodosinAlpha-1A adrenergic receptortarget
SilodosinAlpha-1B adrenergic receptortarget
SilodosinUDP-glucuronosyltransferase 2B7enzyme
AvanafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
AvanafilCytochrome P450 3A4enzyme
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
FesoterodineMuscarinic acetylcholine receptor M1target
FesoterodineMuscarinic acetylcholine receptor M3target
FesoterodineCytochrome P450 3A4enzyme
FesoterodineMuscarinic acetylcholine receptor M2target
FesoterodineMuscarinic acetylcholine receptor M4target
FesoterodineMuscarinic acetylcholine receptor M5target
FesoterodineCytochrome P450 2D6enzyme
FesoterodineP-glycoprotein 1transporter
MirabegronCytochrome P450 3A4enzyme
MirabegronCytochrome P450 2D6enzyme
MirabegronP-glycoprotein 1transporter
MirabegronSolute carrier organic anion transporter family member 1A2transporter
MirabegronSerum albumincarrier
MirabegronAlpha-1-acid glycoprotein 1carrier
MirabegronCholinesteraseenzyme
MirabegronBeta-3 adrenergic receptortarget
MoxisylyteCholinesteraseenzyme
MoxisylyteCytochrome P450 3A Subfamilyenzyme
MoxisylyteAlpha adrenergic receptortarget
Phenyl salicylateProstaglandin G/H synthase 1target
Phenyl salicylateProstaglandin G/H synthase 2target
PropiverineMuscarinic acetylcholine receptor M1target
PropiverineMuscarinic acetylcholine receptor M2target
PropiverineMuscarinic acetylcholine receptor M3target
PropiverineMuscarinic acetylcholine receptor M4target
PropiverineMuscarinic acetylcholine receptor M5target
PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
PropiverineAlpha-1A adrenergic receptortarget
PropiverineCytochrome P450 3A4enzyme
PropiverineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
PropiverineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
TerodilineCytochrome P450 3A4enzyme
ApomorphineDopamine D2 receptortarget
ApomorphineDopamine D1 receptortarget
ApomorphineDopamine D4 receptortarget
ApomorphineDopamine D3 receptortarget
ApomorphineDopamine D5 receptortarget
ApomorphineAlpha-2C adrenergic receptortarget
ApomorphineAlpha-2B adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 2Ctarget
Apomorphine5-hydroxytryptamine receptor 1Atarget
Apomorphine5-hydroxytryptamine receptor 2Atarget
Apomorphine5-hydroxytryptamine receptor 2Btarget
ApomorphineAlpha-2A adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 1Dtarget
Apomorphine5-hydroxytryptamine receptor 1Btarget
ApomorphineCatechol O-methyltransferaseenzyme
ApomorphineSulfotransferase 1A1enzyme
ApomorphineSulfotransferase 1A2enzyme
ApomorphineSulfotransferase 1A3/1A4enzyme
ApomorphineEstrogen sulfotransferaseenzyme
ApomorphineSulfotransferase family cytosolic 1B member 1enzyme
ApomorphineCytochrome P450 2B6enzyme
ApomorphineCytochrome P450 2C8enzyme
ApomorphineCytochrome P450 3A4enzyme
ApomorphineCytochrome P450 3A5enzyme
ApomorphineUDP-glucuronosyltransferases (UGTs)enzyme
ApomorphineSerum albumincarrier
ApomorphineSynaptic vesicular amine transportertransporter
Dimethyl sulfoxideTransthyretincarrier
Dimethyl sulfoxideCytochrome P450 2C19enzyme
Dimethyl sulfoxideCytochrome P450 2D6enzyme
Dimethyl sulfoxideCytochrome P450 3A4enzyme
PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
MepartricinCytochrome P450 3A4enzyme
TioproninMyeloperoxidaseenzyme
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter