Antiparasitic Products, Insecticides and Repellents

DrugDrug NameDrug Indication
DB00205PyrimethamineFor the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine
DB00336NitrofuralFor the treatment of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
DB00358MefloquineFor the treatment of mild to moderate acute malaria caused by Mefloquineuine-susceptible strains of Plasmodium falciparum (both chloroquine-susceptible and resistant strains) or by Plasmodium vivax. Also for the prophylaxis of Plasmodium falciparum and Plasmodium vivax malaria infections, including prophylaxis of chloroquine-resistant strains of Plasmodium falciparum.
DB00431LindaneFor the treatment of patients infested with Sarcoptes scabiei or pediculosis capitis who have either failed to respond to adequate doses, or are intolerant of other approved therapies.
DB00468QuinineFor the treatment of malaria and leg cramps
DB00507NitazoxanideFor the treatment of diarrhea in adults and children caused by the protozoa Giardia lamblia, and for the treatment of diarrhea in children caused by the protozoan, Cryptosporidium parvum [FDA label]. Nitazoxanide has not been shown to be superior to placebo medication for the management of diarrhea caused by Cryptosporidium parvum in patients with HIV/immunodeficiency [FDA label, A31973, A31976].
DB00518AlbendazoleFor the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
DB00592PiperazineUsed as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
DB00608ChloroquineFor the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis
DB00613AmodiaquineFor treatment of acute malarial attacks in non-immune subjects.
DB00643MebendazoleFor the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.
DB00676Benzyl benzoateUsed to kill lice and the mites responsible for the skin condition scabies.
DB00711DiethylcarbamazineUsed for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
DB00730ThiabendazoleFor the treatment of strongyloidiasis (threadworm), cutaneous larva migrans (creeping eruption), visceral larva migrans, and trichinosis.
DB00738PentamidineFor the treatment of pneumonia due to Pneumocystis carinii.
DB00772MalathionFor patients infected with Pediculus humanus capitis (head lice and their ova) of the scalp hair.
DB00822DisulfiramFor the treatment and management of chronic alcoholism
DB00848LevamisoleFor adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer. Levamisole was originally used as an antihelminthic to treat worm infestations in both humans and animals.
DB01058PraziquantelFor the treatment of infections due to all species of schistosoma.
DB01087PrimaquineFor the treatment of malaria.
DB01096OxamniquineFor treatment of Schistosomiasis caused by Schistosoma mansoni
DB01103QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
DB01117AtovaquoneFor the treatment or prevention of Pneumocystis carinii pneumonia in patients who are intolerant to trimethoprim-sulfamethoxazole (TMP-SMX). Also indicated for the acute oral treatment of mild to moderate PCP in patients who are intolerant to TMP-SMX.
DB01131ProguanilFor the causal prevention and suppression of malaria caused by susceptible strains of P. falciparum and other species of Plasmodium found in some geographical areas of the world.
DB01157TrimetrexateFor use, with concurrent leucovorin administration (leucovorin protection), as an alternative therapy for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients, including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer.
DB01218HalofantrineFor treatment of Severe malaria
DB01611HydroxychloroquineFor the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis.
DB02640FumagillinNot Available
DB04786SuraminFor treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
DB04813BithionolNot Available
DB04930PermethrinFor the treatment of infestation with Sarcoptes scabiei (scabies).
DB05630Sodium stibogluconateFor the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB06243EflornithineEflornithine is indicated in the treatment of facial hirsutism (excessive hair growth).
DB06697ArtemetherArtemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the Plasmodium species has not been identified. Indicated for use in adults and children greater than 5 kg.
DB06708LumefantrineLumefantrine and artemether combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the Plasmodium species has not been identified. Indicated for use in adults and children greater than 5 kg.
DB06770Benzyl alcoholUlesfia (benzyl alcohol) lotion is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia Lotion does not have ovicidal activity.
DB06803NiclosamideFor the treatment of tapeworm and intestinal fluke infections: Taenia saginata (Beef Tapeworm), Taenia solium (Pork Tapeworm), Diphyllobothrium latum (Fish Tapeworm), Fasciolopsis buski (large intestinal fluke). Niclosamide is also used as a molluscicide in the control of schistosomiasis.
DB06816PyrviniumPyrvinium was once used in the treatment of pinworm infestations [T39].
DB08792DiloxanideDiloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with other agents such as the nitroimidazoles (eg. metronidazole) in the treatment of invasive or extraintestinal forms of amebiasis.
DB08928ArsthinolAntiprotozoal agent effective against amoebiasis and yaws.
DB08974FlubendazoleNot Available
DB09274ArtesunateFor the treatment of severe malaria caused by *Plasmodium falciparum* in adults and children [L891]
DB11156PyrantelFor the treatment of enterobiasis including roundworm (ascariasis), pinworm (enterobius) and hookworm (strongyloides) and hookworm (ancylostoma) in the pyrantel pamoate form [L1893]. Pyrantel is available in various formulations for humans, dogs, and cats as the pamoate (US Pharmacopeia nomenclature) or embonate (European Pharmacopoeia nomenclature) salt, which contains 34.7% pyrantel base combined with pamoic acid [L1893]. [L1900], [A32283]. Pyrantel pamoate (embonate) ingested orally is effective for removal and control of ascarid and hookworm infections in puppies and dogs (adult Toxocara canis, Toxascaris leonina, Ancylostoma tubaeforme, An. braziliense, Uncinaria stenocephala), cats (adult Toxocara cati, Toxa. leonina, An. caninum, An. braziliense, U. stenocephala), horses and ponies (adult and immature Parascaris equorum, adult Strongylus vulgaris, S. edentatus, S. equinus, Cyathostomes (Triodontophorus spp., Cyathostomum spp., Cylicodontophorus spp., Cylicocyclus spp., Cylicostephanus spp., Poteriostomum spp.), Oxyuris equi, Anoplocephala perfoliata), swine (adult Ascaris suum, Oesophagostomum dentatum), and humans (adult A. lumbricoides, Enterobius vermicularis, An. duodenale, Necator americanus) [L1900].
DB11282DiethyltoluamideDiethyltoluamide, or DEET, is an active ingredient that is predominantly indicated for as an insect repellant used to repel biting pests like mosquitoes and ticks [L2774]. Products containing DEET currently are available to the public in a variety of liquids, lotions, sprays, and impregnated materials like towelettes or roll-ons [L2774].
DB11473MetrifonateNot Available
DB11638ArtenimolFor the treatment of uncomplicated *Plasmodium falciparum* infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with [DB13941].
DB11820NifurtimoxNot Available
DB11989BenznidazoleFor use in the treatment of Chagas disease in children 2-12 years of age [L939].
DB12172NimorazoleNot Available
DB12245TriclabendazoleThis drug is indicated for the treatment of fascioliasis in patients 6 years of age and older [FDA label], [L5452].
DB12864MelarsoprolNot Available
DB12975PyronaridineNot Available
DB13132ArtemisininNot Available
DB13205TeclozanNot Available
DB13245ThiramNot Available
DB13263QuassiaNot Available
DB13732Meglumine antimoniateNot Available
DB13746BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
DB13851ArtemotilNot Available
DB13941PiperaquineFor the treatment of uncomplicated *Plasmodium falciparum* infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with [DB11638].
DB00602IvermectinFor the treatment of intestinal (i.e., nondisseminated) strongyloidiasis due to the nematode parasite Strongyloides stercoralis. Also for the treatment of onchocerciasis (river blindness) due to the nematode parasite Onchocerca volvulus. Can be used to treat scabies caused by Sarcoptes scabiei.
DB00911TinidazoleFor the treatment of trichomoniasis caused by T. vaginalis in both female and male patients. Also for the treatment of giardiasis caused by G. duodenalis in both adults and pediatric patients older than three years of age and for the treatment of intestinal amebiasis and amebic liver abscess caused by E. histolytica in both adults and pediatric patients older than three years of age.
DB00916MetronidazoleFor the treatment of anaerobic infections and mixed infections, surgical prophylaxis requiring anaerobic coverage, Clostridium difficile-associated diarrhea and colitis, Helicobacter pylori infection and duodenal ulcer disease, bacterial vaginosis, Giardia lamblia gastro-enteritis, amebiasis caused by Entamoeba histolytica, acne rosacea (topical treatment), and Trichomonas infections.
DB04815ClioquinolUsed as a topical antifungal treatment.
DB12834SecnidazoleIndicated for the treatment of bacterial vaginosis in adult women .
DB13026OrnidazoleNot Available
DB13268AcetarsolAcetarsol has been used for the treatment of different diseases such as syphilis, amoebiasis, yaws, trypanosomiasis, and malaria.[L2624] Acetarsol was used commonly for the treatment of vaginitis due to _Trichomonas vaginalis_ and _Candida albicans_.[A32839, A32841] When orally administered, acetarsol can be used for the treatment of intestinal amoebiasis and in the form of suppositories it has been researched for the treatment of proctitis.[L2626] Protozoan infections are parasitic diseases characterized to be caused by organisms classified in the kingdom Protozoa which is formed by a great diversity of organisms.[L2627]
DB13306ChlorquinaldolNot Available
DB12265FexinidazoleNot Available
DB13865DehydroemetineNot Available
DrugDrug NameTargetType
DB00205PyrimethamineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB00205PyrimethamineDihydrofolate reductasetarget
DB00205PyrimethamineCytochrome P450 2C8enzyme
DB00205PyrimethamineBeta-hexosaminidase subunit betatarget
DB00205PyrimethamineMultidrug and toxin extrusion protein 1transporter
DB00205PyrimethamineMultidrug and toxin extrusion protein 2transporter
DB00336NitrofuralPyruvate dehydrogenase [ubiquinone]target
DB00336NitrofuralGlutathione reductasetarget
DB00336NitrofuralMalate dehydrogenasetarget
DB00336Nitrofural[Citrate [pro-3S]-lyase] ligasetarget
DB00336NitrofuralXanthine dehydrogenase/oxidaseenzyme
DB00358MefloquineHemoglobin subunit alphatarget
DB00358MefloquineCholinesteraseenzyme
DB00358MefloquineCytochrome P450 3A4enzyme
DB00358MefloquineAdenosine receptor A2atarget
DB00358MefloquineFe(II)-protoporphyrin IXtarget
DB00358MefloquineMultidrug resistance protein 1transporter
DB00358MefloquineCytochrome P450 19A1enzyme
DB00358MefloquineCytochrome P450 2D6enzyme
DB00358MefloquineAcetylcholinesteraseenzyme
DB00431LindaneGamma-aminobutyric acid receptor subunit beta-1target
DB00431LindaneGlycine receptor subunit alpha-1target
DB00431LindaneGlycine receptor subunit alpha-2target
DB00431LindaneGlycine receptor subunit alpha-3target
DB00431LindaneGlycine receptor subunit betatarget
DB00431LindaneGamma-aminobutyric acid receptor subunit beta-3target
DB00431LindaneGamma-aminobutyric acid receptor subunit rho-1target
DB00431LindaneProgesterone receptortarget
DB00431LindaneEstrogen receptor alphatarget
DB00431LindaneNuclear receptor subfamily 1 group I member 2target
DB00468QuininePlatelet glycoprotein IXtarget
DB00468QuinineIntermediate conductance calcium-activated potassium channel protein 4target
DB00468QuinineCytochrome P450 3A4enzyme
DB00468QuinineCytochrome P450 3A5enzyme
DB00468QuinineCytochrome P450 1A1enzyme
DB00468QuinineCytochrome P450 2D6enzyme
DB00468QuinineCytochrome P450 1A2enzyme
DB00468QuinineCytochrome P450 2C8enzyme
DB00468QuinineCytochrome P450 2C9enzyme
DB00468QuinineCytochrome P450 2C19enzyme
DB00468QuinineCytochrome P450 2E1enzyme
DB00468QuinineCytochrome P450 3A7enzyme
DB00468QuinineSolute carrier family 22 member 2transporter
DB00468QuinineSolute carrier family 22 member 1transporter
DB00468QuinineSolute carrier family 22 member 5transporter
DB00468QuinineMultidrug resistance protein 1transporter
DB00468QuinineSolute carrier organic anion transporter family member 1A2transporter
DB00468QuinineSolute carrier family 22 member 4transporter
DB00468QuinineFe(II)-protoporphyrin IXtarget
DB00468QuinineSolute carrier organic anion transporter family member 1B1transporter
DB00507NitazoxanidePyruvate-flavodoxin oxidoreductasetarget
DB00507NitazoxanidePyruvate-flavodoxin oxidoreductaseenzyme
DB00507NitazoxanideFolate transporter 1carrier
DB00518AlbendazoleTubulin alpha-1A chaintarget
DB00518AlbendazoleTubulin beta-4B chaintarget
DB00518AlbendazoleCytochrome P450 3A4enzyme
DB00518AlbendazoleFumarate reductase flavoprotein subunittarget
DB00518AlbendazoleMultidrug resistance protein 1transporter
DB00518AlbendazoleCytochrome P450 1A1enzyme
DB00518AlbendazoleCytochrome P450 1A2enzyme
DB00518AlbendazoleTubulin beta-2 chaintarget
DB00518AlbendazoleCytochrome P450 2C19enzyme
DB00592PiperazineGamma-aminobutyric acid receptor subunit beta-3target
DB00592PiperazineCytochrome P450 2D6enzyme
DB00608ChloroquineTumor necrosis factortarget
DB00608ChloroquineToll-like receptor 9target
DB00608ChloroquineGlutathione S-transferase A2target
DB00608ChloroquineCytochrome P450 2D6enzyme
DB00608ChloroquineCytochrome P450 3A4enzyme
DB00608ChloroquineCytochrome P450 1A1enzyme
DB00608ChloroquineCytochrome P450 2C8enzyme
DB00608ChloroquineCytochrome P450 3A5enzyme
DB00608ChloroquineFe(II)-protoporphyrin IXtarget
DB00608ChloroquineGlutathione S-transferasetarget
DB00608ChloroquineMultidrug resistance protein 1transporter
DB00613AmodiaquineHistamine N-methyltransferasetarget
DB00613AmodiaquineCytochrome P450 2C8enzyme
DB00613AmodiaquineCytochrome P450 2D6enzyme
DB00613AmodiaquineFe(II)-protoporphyrin IXtarget
DB00613AmodiaquineCytochrome P450 1A1enzyme
DB00613AmodiaquineCytochrome P450 1B1enzyme
DB00613AmodiaquineCytochrome P450 2C9enzyme
DB00613AmodiaquineMultidrug resistance protein 1transporter
DB00643MebendazoleTubulin alpha-1A chaintarget
DB00643MebendazoleTubulin beta-4B chaintarget
DB00643MebendazoleCytochrome P450 3A4enzyme
DB00643MebendazoleCytochrome P450 1A1enzyme
DB00711DiethylcarbamazineArachidonate 5-lipoxygenasetarget
DB00711DiethylcarbamazineProstaglandin G/H synthase 1target
DB00711DiethylcarbamazineCholinesteraseenzyme
DB00730ThiabendazoleFumarate reductase flavoprotein subunittarget
DB00730ThiabendazoleCytochrome P450 1A2enzyme
DB00730ThiabendazoleCytochrome P450 1A1enzyme
DB00738PentamidineDNAtarget
DB00738PentamidineCytochrome P450 2C19enzyme
DB00738PentamidinetRNA (cytosine(38)-C(5))-methyltransferasetarget
DB00738PentamidineCytochrome P450 2C8enzyme
DB00738PentamidineCytochrome P450 2D6enzyme
DB00738PentamidineCytochrome P450 1A1enzyme
DB00738PentamidineCytochrome P450 3A5enzyme
DB00738PentamidineCytochrome P450 4A11enzyme
DB00772MalathionCholinesterasetarget
DB00772MalathionCytochrome P450 1A2enzyme
DB00772MalathionCytochrome P450 2B6enzyme
DB00822DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DB00822DisulfiramCytochrome P450 2E1enzyme
DB00822DisulfiramDopamine beta-hydroxylasetarget
DB00822DisulfiramCytochrome P450 3A4enzyme
DB00822DisulfiramCytochrome P450 3A5enzyme
DB00822DisulfiramBile salt export pumptransporter
DB00848LevamisoleNeuronal acetylcholine receptor subunit alpha-3target
DB00848LevamisoleAlkaline phosphatase, placental-liketarget
DB00848LevamisoleAcetylcholine receptor subunit alpha-type unc-38target
DB00848LevamisoleAcetylcholine receptor subunit alpha-type unc-63target
DB00848LevamisoleAcetylcholine receptor subunit beta-type lev-1target
DB00848LevamisoleAcetylcholine receptor subunit beta-type unc-29target
DB01058PraziquantelSchistosome calcium ion (Ca2+) channelstarget
DB01058PraziquantelCytochrome P450 3A4enzyme
DB01058PraziquantelCytochrome P450 1A2enzyme
DB01058PraziquantelCytochrome P450 2C19enzyme
DB01058PraziquantelCytochrome P450 3A43enzyme
DB01058PraziquantelCytochrome P450 3A5enzyme
DB01058PraziquantelCytochrome P450 3A7enzyme
DB01087PrimaquineCytochrome P450 1A1enzyme
DB01087PrimaquineCytochrome P450 1A2enzyme
DB01087PrimaquineCytochrome P450 3A4enzyme
DB01087PrimaquineKeratin, type II cytoskeletal 7target
DB01087PrimaquineCytochrome P450 1B1enzyme
DB01087PrimaquineCytochrome P450 2D6enzyme
DB01087PrimaquineRibosyldihydronicotinamide dehydrogenase [quinone]target
DB01087PrimaquineFe(II)-protoporphyrin IXtarget
DB01087PrimaquineMultidrug resistance protein 1transporter
DB01096OxamniquineDNAtarget
DB01096OxamniquineCytochrome P450 2D6enzyme
DB01103QuinacrineDNAtarget
DB01103Quinacrine85/88 kDa calcium-independent phospholipase A2target
DB01103QuinacrineCytosolic phospholipase A2target
DB01103QuinacrineInactive phospholipase C-like protein 1target
DB01103QuinacrineHistamine N-methyltransferaseenzyme
DB01103QuinacrineSolute carrier family 22 member 2transporter
DB01103QuinacrineMultidrug resistance protein 1transporter
DB01103QuinacrineCytochrome P450 3A4enzyme
DB01103QuinacrineCytochrome P450 3A5enzyme
DB01117AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01117AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01117AtovaquoneCytochrome btarget
DB01117AtovaquoneCytochrome P450 2C9enzyme
DB01117AtovaquoneCytochrome P450 3A4enzyme
DB01117AtovaquoneMultidrug resistance protein 1transporter
DB01131ProguanilBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB01131ProguanilDihydrofolate reductasetarget
DB01131ProguanilCytochrome P450 2C19enzyme
DB01131ProguanilCytochrome P450 2D6enzyme
DB01131ProguanilCytochrome P450 2C9enzyme
DB01131ProguanilCytochrome P450 2E1enzyme
DB01131ProguanilCytochrome P450 3A4enzyme
DB01157TrimetrexateDihydrofolate reductasetarget
DB01218HalofantrineFe(II)-protoporphyrin IXtarget
DB01218HalofantrinePotassium voltage-gated channel subfamily H member 2target
DB01218HalofantrineCytochrome P450 3A4enzyme
DB01218HalofantrineCytochrome P450 2D6enzyme
DB01218HalofantrinePlasmepsin-2target
DB01218HalofantrineCytochrome P450 2C8enzyme
DB01218HalofantrineCytochrome P450 3A5enzyme
DB01611HydroxychloroquineDNAtarget
DB01611HydroxychloroquineToll-like receptor 7target
DB01611HydroxychloroquineToll-like receptor 9target
DB01611HydroxychloroquineCytochrome P450 2D6enzyme
DB01611HydroxychloroquineMultidrug resistance protein 1transporter
DB02640FumagillinMethionine aminopeptidase 2target
DB04786SuraminNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
DB04786SuraminComplement control protein C3target
DB04786SuraminPhospholipase A2, membrane associatedtarget
DB04786SuraminProthrombintarget
DB04786SuraminP2Y purinoceptor 2target
DB04786SuraminFollicle-stimulating hormone receptortarget
DB04786SuraminRyanodine receptor 1target
DB04786SuraminArylsulfatase Aenzyme
DB04786SuraminCytosolic phospholipase A2enzyme
DB04930PermethrinCytochrome P450 2B6enzyme
DB04930PermethrinCytochrome P450 3A4enzyme
DB04930PermethrinSodium channel protein type 1 subunit alphatarget
DB04930PermethrinEstrogen receptor alphatarget
DB04930PermethrinNuclear receptor subfamily 1 group I member 2target
DB05630Sodium stibogluconateDNA topoisomerase 1target
DB06243EflornithineOrnithine decarboxylasetarget
DB06697ArtemetherCytochrome P450 3A4enzyme
DB06697ArtemetherCytochrome P450 3A5enzyme
DB06697ArtemetherCytochrome P450 2B6enzyme
DB06697ArtemetherCytochrome P450 2C9enzyme
DB06697ArtemetherCytochrome P450 2C19enzyme
DB06697ArtemetherCytochrome P450 2D6enzyme
DB06708LumefantrineCytochrome P450 2D6enzyme
DB06708LumefantrineCytochrome P450 3A4enzyme
DB06770Benzyl alcoholCytochrome P450 2C8enzyme
DB06770Benzyl alcoholCytochrome P450 1A1enzyme
DB06770Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
DB06770Benzyl alcoholCytochrome P450 1A2enzyme
DB06770Benzyl alcoholCytochrome P450 2E1enzyme
DB06770Benzyl alcoholCytochrome P450 2D6enzyme
DB06803NiclosamideDNAtarget
DB06803NiclosamideCytochrome P450 2C9enzyme
DB06803NiclosamideCytochrome P450 1A2enzyme
DB09274ArtesunateMalaria protein EXP-1target
DB09274ArtesunateCytochrome P450 2A6enzyme
DB09274ArtesunateCytochrome P450 3A4enzyme
DB11156PyrantelG-protein coupled receptor 35target
DB11156PyrantelCytochrome P450 4A11enzyme
DB11156PyrantelMuscarinic acetylcholine receptor M1target
DB11638ArtenimolActin, cytoplasmic 2target
DB11638ArtenimolAlpha-aminoadipic semialdehyde dehydrogenasetarget
DB11638ArtenimolAnnexin A2target
DB11638ArtenimolATP synthase subunit alpha, mitochondrialtarget
DB11638ArtenimolATP synthase subunit g, mitochondrialtarget
DB11638ArtenimolATP synthase subunit O, mitochondrialtarget
DB11638ArtenimolCalpastatintarget
DB11638ArtenimolT-complex protein 1 subunit gammatarget
DB11638ArtenimolCofilin-1target
DB11638ArtenimolChloride intracellular channel protein 1target
DB11638ArtenimolCysteine and glycine-rich protein 1target
DB11638ArtenimolDihydropyrimidinase-related protein 2target
DB11638ArtenimolDesmoplakintarget
DB11638ArtenimolElongation factor 1-alpha 1target
DB11638ArtenimolAlpha-enolasetarget
DB11638ArtenimolFilamin-Atarget
DB11638ArtenimolAlpha-ketoglutarate-dependent dioxygenase FTOtarget
DB11638ArtenimolGlucose-6-phosphate 1-dehydrogenasetarget
DB11638ArtenimolGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
DB11638ArtenimolGlucose-6-phosphate isomerasetarget
DB11638ArtenimolHeterogeneous nuclear ribonucleoproteins A2/B1target
DB11638ArtenimolHeterogeneous nuclear ribonucleoprotein D0target
DB11638ArtenimolHeterogeneous nuclear ribonucleoprotein Ktarget
DB11638ArtenimolHeterochromatin protein 1-binding protein 3target
DB11638ArtenimolHeat shock protein beta-1target
DB11638ArtenimolRas GTPase-activating-like protein IQGAP1target
DB11638ArtenimolFar upstream element-binding protein 2target
DB11638ArtenimolL-lactate dehydrogenase A chaintarget
DB11638ArtenimolL-lactate dehydrogenase B chaintarget
DB11638ArtenimolGalectin-1target
DB11638ArtenimolMicrotubule-associated protein 4target
DB11638ArtenimolMalate dehydrogenase, cytoplasmictarget
DB11638ArtenimolPuromycin-sensitive aminopeptidasetarget
DB11638ArtenimolProfilin-1target
DB11638ArtenimolPhosphoglycerate kinase 1target
DB11638ArtenimolPyruvate kinase PKMtarget
DB11638ArtenimolPeptidyl-prolyl cis-trans isomerase Atarget
DB11638ArtenimolPeroxiredoxin-1target
DB11638Artenimol60S ribosomal protein L10target
DB11638Artenimol60S ribosomal protein L14target
DB11638Artenimol60S ribosomal protein L18target
DB11638Artenimol60S ribosomal protein L23atarget
DB11638Artenimol60S ribosomal protein L35target
DB11638Artenimol60S ribosomal protein L4target
DB11638Artenimol40S ribosomal protein S13target
DB11638Artenimol40S ribosomal protein S17target
DB11638Artenimol40S ribosomal protein S18target
DB11638Artenimol40S ribosomal protein S19target
DB11638Artenimol40S ribosomal protein S28target
DB11638Artenimol40S ribosomal protein S5target
DB11638Artenimol40S ribosomal protein S6target
DB11638Artenimol40S ribosomal protein S8target
DB11638Artenimol40S ribosomal protein S9target
DB11638ArtenimolSplicing factor 1target
DB11638ArtenimolSplicing factor, proline- and glutamine-richtarget
DB11638ArtenimolSmall nuclear ribonucleoprotein Sm D2target
DB11638ArtenimolSignal recognition particle 14 kDa proteintarget
DB11638ArtenimolSerine/arginine-rich splicing factor 4target
DB11638ArtenimolTransgelintarget
DB11638ArtenimolTransgelin-2target
DB11638ArtenimolTriosephosphate isomerasetarget
DB11638ArtenimolTropomyosin alpha-1 chaintarget
DB11638ArtenimolTubulin alpha-1A chaintarget
DB11638ArtenimolVimentintarget
DB11638ArtenimolZyxintarget
DB11638ArtenimolHeat shock cognate 71 kDa proteintarget
DB11638ArtenimolTubulin beta-6 chaintarget
DB11638ArtenimolTubulin beta-4A chaintarget
DB11638ArtenimolTubulin beta chaintarget
DB11638ArtenimolFructose-bisphosphate aldolase Atarget
DB11638ArtenimolGlyceraldehyde-3-phosphate dehydrogenasetarget
DB11638ArtenimolCytochrome ctarget
DB11638ArtenimolPhosphoglycerate mutase 1target
DB11638ArtenimolMyosin-9target
DB11638ArtenimolProtein disulfide-isomerasetarget
DB11638ArtenimolProbable ATP-dependent RNA helicase DDX5target
DB11638ArtenimolSerine hydroxymethyltransferase, mitochondrialtarget
DB11638ArtenimolSpliceosome RNA helicase DDX39Btarget
DB11638ArtenimolNucleophosmintarget
DB11638ArtenimolTranslationally-controlled tumor protein homologtarget
DB11638ArtenimolP-type Ca2+-transporting ATPasetarget
DB11638ArtenimolOrnithine aminotransferasetarget
DB11638ArtenimolElongation factor 1-alphatarget
DB11638ArtenimolMultidrug resistance proteintarget
DB11638ArtenimolElongation factor 2target
DB11638ArtenimolActin-1target
DB11638ArtenimolGlyceraldehyde-3-phosphate dehydrogenasetarget
DB11638ArtenimolFructose-bisphosphate aldolasetarget
DB11638ArtenimolCell division cycle protein 48 homologue,putativetarget
DB11638ArtenimolHeat shock protein 90target
DB11638ArtenimolEukaryotic initiation factor 4Atarget
DB11638ArtenimolPyruvate kinasetarget
DB11638ArtenimolL-lactate dehydrogenasetarget
DB11638ArtenimolProtein disulfide-isomerasetarget
DB11638ArtenimolThioredoxin-related protein, putativetarget
DB11638ArtenimolSpermidine synthasetarget
DB11638ArtenimolProbable ATP-dependent 6-phosphofructokinasetarget
DB11638ArtenimolGlutamate dehydrogenasetarget
DB11638ArtenimolEndoplasmin homolog, putativetarget
DB11638ArtenimolHypoxanthine-guanine-xanthine phosphoribosyltransferasetarget
DB11638ArtenimolEnolasetarget
DB11638Artenimol40S ribosomal protein S3target
DB11638ArtenimolNon-SERCA-type Ca2+-transporting P-ATPasetarget
DB11638ArtenimolTubulin alpha chaintarget
DB11638ArtenimolKnob-associated histidine-rich proteintarget
DB11638ArtenimolS-adenosylmethionine synthasetarget
DB11638ArtenimolV-type H(+)-translocating pyrophosphatase, putativetarget
DB11638Artenimol60S ribosomal protein L4target
DB11638ArtenimolPhosphoethanolamine N-methyltransferasetarget
DB11638Artenimol40S ribosomal protein S3atarget
DB11638ArtenimolConserved Plasmodium membrane proteintarget
DB11638Artenimol60S ribosomal protein L3target
DB11638ArtenimolHigh molecular weight rhoptry protein 2target
DB11638ArtenimolSerine repeat antigen 5target
DB11638Artenimol40S ribosomal protein S19target
DB11638ArtenimolGlycophorin-binding proteintarget
DB11638ArtenimolCalcium-transporting ATPasetarget
DB11638ArtenimolV-type proton ATPase catalytic subunit Atarget
DB11638Artenimol60S ribosomal protein L2target
DB11638ArtenimolAcyl-CoA synthetasetarget
DB11638ArtenimolPlasmepsin IVtarget
DB11638ArtenimolPlasmepsin-1target
DB11638ArtenimolChloroquine resistance transportertarget
DB11638Artenimol14-3-3 proteintarget
DB11638ArtenimolIsoleucine--tRNA ligase, putativetarget
DB11638ArtenimolPlasmodium exported proteintarget
DB11638ArtenimolTubulin beta chaintarget
DB11638Artenimol60S ribosomal protein L27target
DB11638ArtenimolSec62, putativetarget
DB11638ArtenimolAutophagy-related protein 18, putativetarget
DB11638ArtenimolMature parasite-infected erythrocyte surface antigentarget
DB11638ArtenimolImportin-7, putativetarget
DB11638ArtenimolKaryopherin alphatarget
DB11638ArtenimolPeptidyl-prolyl cis-trans isomerasetarget
DB11638ArtenimolDnaJ protein, putativetarget
DB11638ArtenimolMerozoite surface protein 1target
DB11638ArtenimolGlutamate--tRNA ligasetarget
DB11638ArtenimolT-complex protein 1 subunit etatarget
DB11638ArtenimolPlasmepsin-2target
DB11638ArtenimolChaperone, putativetarget
DB11638ArtenimolRhoptry neck protein 3target
DB11638Artenimol40S ribosomal protein S5, putativetarget
DB11638ArtenimolSkeleton-binding protein 1target
DB11638ArtenimolPurine nucleotide phosphorylase, putativetarget
DB11638ArtenimolAdenosylhomocysteinasetarget
DB11638ArtenimolAdenosine deaminasetarget
DB11638ArtenimolMethionine--tRNA ligasetarget
DB11638ArtenimolCarbamoyl phosphate synthetasetarget
DB11638ArtenimolAspartate carbamoyltransferasetarget
DB11638ArtenimolSignal recognition particle receptor, beta subunittarget
DB11638ArtenimolParasite-infected erythrocyte surface proteintarget
DB11638ArtenimolCoatomer alpha subunit, putativetarget
DB11638ArtenimolHexokinasetarget
DB11638ArtenimolProteasome subunit alpha typetarget
DB11638ArtenimolHaloacid dehalogenase-like hydrolasetarget
DB11638ArtenimolInsulinase, putativetarget
DB11638Artenimol40S ribosomal protein S21target
DB11638ArtenimolUbiquitin-conjugating enzyme E2target
DB11638ArtenimolEukaryotic translation initiation factor 3 subunit Ctarget
DB11638Artenimol60S ribosomal protein L24, putativetarget
DB11638Artenimol60S ribosomal protein L23target
DB11638Artenimol60S ribosomal protein L17, putativetarget
DB11638ArtenimolNADP-specific glutamate dehydrogenasetarget
DB11638ArtenimolHAP proteintarget
DB11638ArtenimolHeat shock protein 110, putativetarget
DB11638Artenimol60S ribosomal protein L10, putativetarget
DB11638ArtenimolLysophospholipase, putativetarget
DB11638ArtenimolPolyadenylate-binding proteintarget
DB11638ArtenimolUbiquitin-60S ribosomal protein L40target
DB11638ArtenimolPhosphoribosylpyrophosphate synthetasetarget
DB11638ArtenimolThioredoxin peroxidase 1target
DB11638ArtenimolProtein transport protein SEC31target
DB11638ArtenimolDipeptidyl aminopeptidase 1target
DB11638ArtenimolRing-infected erythrocyte surface antigentarget
DB11638ArtenimolATP-dependent RNA helicase UAP56target
DB11638ArtenimolCalcium-dependent protein kinase 4target
DB11638ArtenimolGTP-binding nuclear protein Rantarget
DB11638ArtenimolNucleoside transporter 2target
DB11638ArtenimolAnamorsin homologtarget
DB11638ArtenimolGlutamine synthetase, putativetarget
DB11638Artenimol60S ribosomal protein L30e, putativetarget
DB11638ArtenimolCasein kinase 2, alpha subunittarget
DB11638ArtenimolThreonine--tRNA ligasetarget
DB11638ArtenimolcAMP-dependent protein kinase regulatory subunittarget
DB11638ArtenimolElongation factor 1-gamma, putativetarget
DB11638ArtenimolThioredoxin-like proteintarget
DB11638Artenimol60S ribosomal protein L21target
DB11638Artenimol60S ribosomal protein L14, putativetarget
DB11638ArtenimolInner membrane complex sub-compartment protein 3target
DB11638ArtenimolHSP40, subfamily A, putativetarget
DB11638ArtenimolPyridoxal 5'-phosphate synthase subunit Pdx1target
DB11638ArtenimolUDP-glucuronosyltransferase 1-9enzyme
DB11638ArtenimolUDP-glucuronosyltransferase 2B7enzyme
DB11638ArtenimolSerum albumintarget
DB11638ArtenimolCytochrome P450 2D6enzyme
DB11638ArtenimolCytochrome P450 2C19enzyme
DB12245TriclabendazoleCytochrome P450 1A2enzyme
DB12245TriclabendazoleCytochrome P450 2C9enzyme
DB12245TriclabendazoleExcretory Secretory (ES) proteinstarget
DB12245TriclabendazoleCytochrome P450 3A4enzyme
DB12245TriclabendazoleCytochrome P450 1A1enzyme
DB12245TriclabendazoleCytochrome P450 1B1enzyme
DB12245TriclabendazoleCytochrome P450 2C19enzyme
DB12245TriclabendazoleCytochrome P450 2D6enzyme
DB12245TriclabendazoleCytochrome P450 2A6enzyme
DB12245TriclabendazoleCytochrome P450 2C8enzyme
DB12245TriclabendazoleCytochrome P450 2B6enzyme
DB13132ArtemisininCytochrome P450 2B6enzyme
DB13746BioallethrinVoltage gated sodium channeltarget
DB13746BioallethrinSodium channel proteintarget
DB13746BioallethrinVoltage-dependent N-type calcium channeltarget
DB13746BioallethrinVoltage-dependent T-type calcium channeltarget
DB13746BioallethrinVoltage-dependent P/Q-type calcium channeltarget
DB13746BioallethrinVoltage-dependent L-type calcium channeltarget
DB13746BioallethrinCytochrome P450 2C8enzyme
DB13746BioallethrinCytochrome P450 2C9enzyme
DB13746BioallethrinCytochrome P450 2C19enzyme
DB13746BioallethrinCytochrome P450 3A4enzyme
DB13746BioallethrinCytochrome P450 2A1enzyme
DB13746BioallethrinCytochrome P450 1A1enzyme
DB13746BioallethrinCytochrome P450 2C6enzyme
DB13746BioallethrinCytochrome P450 2C11enzyme
DB13746BioallethrinCytochrome P450 3A1enzyme
DB13746BioallethrinCytochrome P450 3A2enzyme
DB13941PiperaquineCytochrome P450 3A4enzyme
DB13941PiperaquineCytochrome P450 2C19enzyme
DB13941PiperaquineCytochrome P450 2C9enzyme
DB13941PiperaquineCytochrome P450 2B6enzyme
DB13941PiperaquineCytochrome P450 2E1enzyme
DB00602IvermectinGamma-aminobutyric acid receptor subunit beta-3target
DB00602IvermectinGlycine receptor subunit alpha-3target
DB00602IvermectinMultidrug resistance protein 1transporter
DB00602IvermectinMultidrug resistance-associated protein 1transporter
DB00602IvermectinCanalicular multispecific organic anion transporter 1transporter
DB00602IvermectinATP-binding cassette sub-family G member 2transporter
DB00602IvermectinCytochrome P450 3A4enzyme
DB00602IvermectinSolute carrier organic anion transporter family member 1B1transporter
DB00602IvermectinSolute carrier organic anion transporter family member 1B3transporter
DB00911TinidazoleCytochrome P450 3A4enzyme
DB00911TinidazoleDNAtarget
DB00911TinidazoleBile salt export pumptransporter
DB00916MetronidazoleIron hydrogenase 1target
DB00916MetronidazoleDNAtarget
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleLanosterol 14-alpha demethylasetarget
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme