Synthetic Anticholinergics, Quaternary Ammonium Compounds

Name
Synthetic Anticholinergics, Quaternary Ammonium Compounds
Accession Number
DBCAT002229
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
OxyphenoniumFor the treatment of visceral spasms
TridihexethylUsed as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus
MethanthelineFor the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children.
GlycopyrroniumAn anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
IsopropamideFor the treatment of a wide range of gastrointestinal disorders, including such conditions as peptic ulcer, gastritis, hyperchlorhydria, functional diarrhea, irritable or spastic colon, pyloroduodenal irritability, pylorospasm, acute nonspecific gastroenteritis,...
MepenzolateA postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
HexocycliumThe World Health Organization classifies hexocyclium as a drug for functional gastrointestinal disorders . Like other anti-muscarinic agents, hexocyclium was likely used to treat peptic ulcers or diarrhea.
PrifiniumPrifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome .
BenziloneNot Annotated
PoldineNot Annotated
BevoniumNot Annotated
Tiemonium iodideNot Annotated
PenthienateNot Annotated
DiphemanilUsed in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration).
FenpiveriniumNot Annotated
Emetonium iodideNot Annotated
TimepidiumNot Annotated
PropanthelineAn antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder.
OtiloniumNot Annotated
PipenzolateNot Annotated
OxitropiumOxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive.
MethscopolamineMethscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The...
Drugs & Drug Targets
DrugTargetType
OxyphenoniumMuscarinic acetylcholine receptor M1target
TridihexethylMuscarinic acetylcholine receptor M1target
TridihexethylMuscarinic acetylcholine receptor M2target
TridihexethylMuscarinic acetylcholine receptor M3target
MethanthelineMuscarinic acetylcholine receptor M1target
MethanthelineHistamine H2 receptortarget
MethanthelineMuscarinic acetylcholine receptor M2target
MethanthelineMuscarinic acetylcholine receptor M3target
MethanthelineMuscarinic acetylcholine receptor M4target
MethanthelineMuscarinic acetylcholine receptor M5target
MethanthelineAcetylcholinesteraseenzyme
GlycopyrroniumMuscarinic acetylcholine receptor M1target
GlycopyrroniumMuscarinic acetylcholine receptor M3target
GlycopyrroniumMuscarinic acetylcholine receptor M2target
IsopropamideMuscarinic acetylcholine receptor M3target
IsopropamideMuscarinic acetylcholine receptor M4target
MepenzolateMuscarinic acetylcholine receptor M1target
MepenzolateMuscarinic acetylcholine receptor M3target
HexocycliumMuscarinic acetylcholine receptor M1target
HexocycliumMuscarinic acetylcholine receptor M2target
HexocycliumMuscarinic acetylcholine receptor M3target
HexocycliumMuscarinic acetylcholine receptor M4target
DiphemanilMuscarinic acetylcholine receptor M3target
PropanthelineMuscarinic acetylcholine receptor M1target
OtiloniumCytochrome P450 3A4enzyme