Synthetic Anticholinergics, Quaternary Ammonium Compounds

DrugDrug NameDrug Indication
DB00219OxyphenoniumFor the treatment of visceral spasms
DB00505TridihexethylUsed as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus
DB00940MethanthelineFor the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children.
DB00986GlycopyrroniumFor use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and free acidity of gastric secretions and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. Also used to treat chronic obstructive pulmonary disease (COPD).
DB01625IsopropamideFor the treatment of a wide range of gastrointestinal disorders, including such conditions as peptic ulcer, gastritis, hyperchlorhydria, functional diarrhea, irritable or spastic colon, pyloroduodenal irritability, pylorospasm, acute nonspecific gastroenteritis, biliary dyskinesia and chronic cholelithiasis, duodenitis, gastrointestinal spasm; it may also be used to treat genitourinary spasm.
DB04843MepenzolateFor use as adjunctive therapy in the treatment of peptic ulcer. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
DB06787HexocycliumThe World Health Organization classifies hexocyclium as a drug for functional gastrointestinal disorders [L876]. Like other anti-muscarinic agents, hexocyclium was likely used to treat peptic ulcers or diarrhea.
DB13254PrifiniumNot Available
DB13369BenziloneNot Available
DB13507PoldineNot Available
DB13542BevoniumNot Available
DB13666Tiemonium iodideNot Available
DB13695PenthienateNot Available
DB13720DiphemanilUsed in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration).
DB13759FenpiveriniumNot Available
DB13769Emetonium iodideNot Available
DB13850TimepidiumNot Available
DB00782PropanthelineFor the treatment of enuresis. It has also been used for hyperhidrosis, and cramps or spasms of the stomach, intestines or bladder.
DB13500OtiloniumNot Available
DB13844PipenzolateNot Available
DB12086OxitropiumNot Available
DB11315MethscopolamineNot Available