Corticosteroids, Potent (Group III)

DrugDrug NameDrug Description
DB00588Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DB00223DiflorasoneA topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort.
DB00288AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
DB00394Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
DB00547DesoximetasoneA glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB00596UlobetasolA lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB00764MometasoneA corticosteroid used to treat asthma and allergic rhinitis.
DB01130PrednicarbateA medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.
DB01222BudesonideA corticosteroid used in the management of asthma, nasal polyposis, and rhinitis via inhalation, as well as mild to moderate active Crohn's disease and ulcerative colitis via ingestion.
DB06781DifluprednateA topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.
DB13728HalometasoneNot Annotated
DB13856FlucloroloneNot Annotated
DB13867FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
DB00443BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
DB00846FlurandrenolideA corticosteroid used to treat corticosteroid-responsive dermatoses.
DB01047FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
DB08971FluocortoloneFluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
DB09095DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
DB14538Hydrocortisone aceponateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
DB14643Methylprednisolone aceponateNot Annotated
DrugDrug NameTargetType
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateP-glycoprotein 1carrier
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DB00223DiflorasoneGlucocorticoid receptortarget
DB00288AmcinonideGlucocorticoid receptortarget
DB00288AmcinonideAnnexin A1target
DB00288AmcinonideCytochrome P450 3A4enzyme
DB00288AmcinonideCytochrome P450 3A5enzyme
DB00394Beclomethasone dipropionateCorticosteroid-binding globulincarrier
DB00394Beclomethasone dipropionateGlucocorticoid receptortarget
DB00394Beclomethasone dipropionateCytochrome P450 3A5enzyme
DB00394Beclomethasone dipropionateCytochrome P450 3A4enzyme
DB00394Beclomethasone dipropionateP-glycoprotein 1transporter
DB00394Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
DB00547DesoximetasoneGlucocorticoid receptortarget
DB00596UlobetasolCorticosteroid-binding globulincarrier
DB00596UlobetasolGlucocorticoid receptortarget
DB00764MometasoneGlucocorticoid receptortarget
DB00764MometasoneCytochrome P450 2C8enzyme
DB00764MometasoneProgesterone receptortarget
DB00764MometasoneCytochrome P450 3A4enzyme
DB00764MometasoneCytochrome P450 3A5enzyme
DB01130PrednicarbateGlucocorticoid receptortarget
DB01130PrednicarbateCytochrome P450 3A4enzyme
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB01222BudesonideCytochrome P450 3A5enzyme
DB01222BudesonideBile salt export pumptransporter
DB01222BudesonideP-glycoprotein 1transporter
DB06781DifluprednateGlucocorticoid receptortarget
DB06781DifluprednateCytochrome P450 3A4enzyme
DB13728HalometasoneCytochrome P450 3A4enzyme
DB13728HalometasoneCytochrome P450 3A5enzyme
DB13867FluticasoneCytochrome P450 3A4enzyme
DB13867FluticasoneCytochrome P450 2C8enzyme
DB13867FluticasoneP-glycoprotein 1carrier
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1carrier
DB13867FluticasoneP-glycoprotein 1transporter
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1transporter
DB13867FluticasoneGlucocorticoid receptortarget
DB13867FluticasoneCorticosteroid-binding globulincarrier
DB13867FluticasoneCytochrome P450 3A5enzyme
DB13867FluticasoneCytochrome P450 3A7enzyme
DB13867FluticasoneProgesterone receptortarget
DB13867FluticasoneCytosolic phospholipase A2target
DB13867FluticasoneMineralocorticoid receptortarget
DB00443BetamethasoneGlucocorticoid receptortarget
DB00443BetamethasoneCytochrome P450 3A4enzyme
DB00443BetamethasoneP-glycoprotein 1transporter
DB00443BetamethasoneCytochrome P450 19A1enzyme
DB00443BetamethasoneCytochrome P450 3A5enzyme
DB00846FlurandrenolideCorticosteroid-binding globulincarrier
DB00846FlurandrenolideGlucocorticoid receptortarget
DB00846FlurandrenolideCytochrome P450 3A4enzyme
DB01047FluocinonideCorticosteroid-binding globulincarrier
DB01047FluocinonideGlucocorticoid receptortarget
DB01047FluocinonideSmoothened homologtarget
DB01047FluocinonideCytochrome P450 3A4enzyme
DB01047FluocinonideCytochrome P450 3A5enzyme
DB08971FluocortoloneCytochrome P450 3A4enzyme
DB08971FluocortoloneCytochrome P450 3A5enzyme
DB09095DifluocortoloneAnnexin A3target
DB09095DifluocortoloneGlucocorticoid receptortarget
DB09095DifluocortoloneCytochrome P450 3A4enzyme
DB09095DifluocortoloneCytochrome P450 3A5enzyme
DB14538Hydrocortisone aceponateAnnexin A1target
DB14538Hydrocortisone aceponateGlucocorticoid receptortarget
DB14538Hydrocortisone aceponateSex hormone-binding globulincarrier
DB14538Hydrocortisone aceponateCytochrome P450 3A4enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A5enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A7enzyme
DB14538Hydrocortisone aceponateP-glycoprotein 1transporter
DB14538Hydrocortisone aceponateSolute carrier organic anion transporter family member 1A2transporter
DB14538Hydrocortisone aceponateATP-binding cassette sub-family G member 2transporter
DB14538Hydrocortisone aceponateCytochrome P450 2C8enzyme
DB14538Hydrocortisone aceponateCorticosteroid-binding globulincarrier
DB14538Hydrocortisone aceponateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14538Hydrocortisone aceponate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14538Hydrocortisone aceponateSolute carrier family 22 member 8transporter