Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents

Name
Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents
Accession Number
DBCAT002252
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
StreptomycinAn aminoglycoside antibiotic indicated to treat mycobacterium tuberculosis and various non-tuberculosis infections.
RifaximinA rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
ParomomycinAn aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.
DifenoxinAn antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
AttapulgiteA veterinary antidiarrheal agent used to treat non-infectious diarrhea in animals.
KaolinA natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding.
FidaxomicinA macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection.
Activated charcoalA gastric decontamination agent used in emergency clinical settings as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons.
OpiumA medication used to treat moderate to severe pain.
PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
RacecadotrilRacecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
PhthalylsulfathiazolePhthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
AcetarsolAn anti infective used to treat a wide variety of infections in the body.
NifurzideNot Annotated
BroxyquinolineNot Annotated
SuccinylsulfathiazoleNot Annotated
MontmorilloniteNot Annotated
SulfaguanidineNot Annotated
NifuroxazideNot Annotated
Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
VancomycinA glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.
NystatinA polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
ColistinA polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
NatamycinA macrolide antifungal used to treat fungal infections of the eye.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
Cromoglicic acidA medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
MiconazoleAn antifungal used to treat fungal infections affecting the vagina, mouth and skin.
KanamycinAn aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
TixocortolA corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis.
Loperamide oxideNot Annotated
CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
EluxadolineA mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
Polymyxin BA polymyxin antibiotic used to treat a wide variety of infections in the body.
Drugs & Drug Targets
DrugTargetType
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Amphotericin BErgosteroltarget
Amphotericin BCytochrome P450 3A4enzyme
LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
LoperamideMu-type opioid receptortarget
LoperamideCalmodulintarget
LoperamidePro-opiomelanocortintarget
LoperamideDelta-type opioid receptortarget
LoperamideCytochrome P450 3A4enzyme
LoperamideP-glycoprotein 1transporter
LoperamideKappa-type opioid receptortarget
LoperamideCytochrome P450 2C8enzyme
LoperamideCytochrome P450 2B6enzyme
LoperamideCytochrome P450 2D6enzyme
LoperamideNuclear receptor subfamily 1 group I member 3target
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
DiphenoxylateMu-type opioid receptortarget
DiphenoxylateDelta-type opioid receptortarget
Streptomycin30S ribosomal protein S12target
Streptomycin16S ribosomal RNAtarget
StreptomycinSolute carrier family 22 member 6transporter
StreptomycinProtein-arginine deiminase type-4target
RifaximinDNA-directed RNA polymerase subunit betatarget
RifaximinNuclear receptor subfamily 1 group I member 2target
RifaximinCytochrome P450 3A4enzyme
RifaximinCytochrome P450 2C19enzyme
RifaximinCytochrome P450 2C8enzyme
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
Paromomycin16S ribosomal RNAtarget
Paromomycin30S ribosomal protein S10target
FidaxomicinP-glycoprotein 1transporter
FidaxomicinRNA polymerase sigma factortarget
FidaxomicinCytochrome P450 3A4enzyme
OpiumDelta-type opioid receptortarget
OpiumKappa-type opioid receptortarget
OpiumMu-type opioid receptortarget
OpiumSerum albumincarrier
OpiumBeta-2-microglobulincarrier
OpiumCytochrome P450 2D6enzyme
OpiumCytochrome P450 3A4enzyme
Beclomethasone dipropionateCorticosteroid-binding globulincarrier
Beclomethasone dipropionateGlucocorticoid receptortarget
Beclomethasone dipropionateCytochrome P450 3A5enzyme
Beclomethasone dipropionateCytochrome P450 3A4enzyme
Beclomethasone dipropionateP-glycoprotein 1transporter
Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneP-glycoprotein 1transporter
BetamethasoneCytochrome P450 19A1enzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneSerum albumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
VancomycinD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
VancomycinSerum albumincarrier
Vancomycinalpha1-acid glycoproteincarrier
VancomycinHistamine H1 receptorcarrier
NystatinErgosteroltarget
NystatinSolute carrier organic anion transporter family member 1B1transporter
NystatinSolute carrier organic anion transporter family member 1B3transporter
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneP-glycoprotein 1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneSolute carrier family 22 member 8transporter
Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineCystine/glutamate transportertarget
SulfasalazineATP-binding cassette sub-family G member 2transporter
SulfasalazineCanalicular multispecific organic anion transporter 1transporter
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazineArachidonate 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazineThromboxane-A synthasetarget
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
ColistinBacterial outer membranetarget
NatamycinErgosteroltarget
NatamycinCytochrome P450 3A4enzyme
PrednisoloneCorticosteroid-binding globulincarrier
PrednisoloneCytochrome P450 3A4enzyme
PrednisoloneGlucocorticoid receptortarget
PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
PrednisoloneP-glycoprotein 1transporter
PrednisoloneSerum albumincarrier
Neomycin30S ribosomal protein S12target
Neomycin16S ribosomal RNAtarget
NeomycinExtracellular calcium-sensing receptortarget
Cromoglicic acidCalcium-activated potassium channel subunit alpha-1target
Cromoglicic acidProtein S100-Ptarget
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCalcium-activated potassium channel subunit alpha-1target
MiconazoleCalcium-activated potassium channel subunit beta-1target
MiconazoleCalcium-activated potassium channel subunit beta-2target
MiconazoleCalcium-activated potassium channel subunit beta-3target
MiconazoleCalcium-activated potassium channel subunit beta-4target
MiconazoleIntermediate conductance calcium-activated potassium channel protein 4target
MiconazoleSmall conductance calcium-activated potassium channel protein 1target
MiconazoleSmall conductance calcium-activated potassium channel protein 2target
MiconazoleSmall conductance calcium-activated potassium channel protein 3target
MiconazolePotassium voltage-gated channel subfamily H member 2target
MiconazolePotassium voltage-gated channel subfamily H member 6target
MiconazolePotassium voltage-gated channel subfamily H member 7target
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
Kanamycin30S ribosomal protein S12target
Kanamycin16S ribosomal RNAtarget
KanamycinAminoglycoside 2'-N-acetyltransferaseenzyme
KanamycinKanamycin nucleotidyltransferaseenzyme
KanamycinAminoglycoside 3'-phosphotransferaseenzyme
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
TixocortolGlucocorticoid receptortarget
TixocortolHistone deacetylase 2target
CrofelemerCystic fibrosis transmembrane conductance regulatortarget
CrofelemerAnoctamin-1target
EluxadolineMu-type opioid receptortarget
EluxadolineDelta-type opioid receptortarget
EluxadolineKappa-type opioid receptortarget
EluxadolineSolute carrier organic anion transporter family member 1B1transporter
EluxadolineCanalicular multispecific organic anion transporter 1transporter
EluxadolineSolute carrier family 22 member 8transporter
Polymyxin BBacterial outer membranetarget
Polymyxin BSolute carrier family 15 member 2transporter