Antipropulsives

Name
Antipropulsives
Accession Number
DBCAT002293
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
DifenoxinAn antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
OpiumA medication used to treat moderate to severe pain.
Loperamide oxideNot Annotated
EluxadolineA mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
Drugs & Drug Targets
DrugTargetType
LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
LoperamideMu-type opioid receptortarget
LoperamideCalmodulintarget
LoperamidePro-opiomelanocortintarget
LoperamideDelta-type opioid receptortarget
LoperamideCytochrome P450 3A4enzyme
LoperamideP-glycoprotein 1transporter
LoperamideKappa-type opioid receptortarget
LoperamideCytochrome P450 2C8enzyme
LoperamideCytochrome P450 2B6enzyme
LoperamideCytochrome P450 2D6enzyme
LoperamidePotassium voltage-gated channel subfamily H member 2target
DiphenoxylateMu-type opioid receptortarget
DiphenoxylateDelta-type opioid receptortarget
OpiumDelta-type opioid receptortarget
OpiumKappa-type opioid receptortarget
OpiumMu-type opioid receptortarget
OpiumSerum albumincarrier
OpiumBeta-2-microglobulincarrier
OpiumCytochrome P450 2D6enzyme
OpiumCytochrome P450 3A4enzyme
EluxadolineMu-type opioid receptortarget
EluxadolineDelta-type opioid receptortarget
EluxadolineKappa-type opioid receptortarget
EluxadolineSolute carrier organic anion transporter family member 1B1transporter
EluxadolineCanalicular multispecific organic anion transporter 1transporter
EluxadolineSolute carrier family 22 member 8transporter